cefotetan-3997 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the cefotetan-3997 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACO2 aconitase 2, mitochondrial
ADD2 adducin 2 (beta)
AKAP5 A kinase (PRKA) anchor protein 5
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX5 arachidonate 5-lipoxygenase
ANP32A-IT1 ANP32A intronic transcript 1
APOM apolipoprotein M
ASTN2 astrotactin 2
ATG10 autophagy related 10
BEND5 BEN domain containing 5
C10ORF12 chromosome 10 open reading frame 12
C11ORF1 chromosome 11 open reading frame 1
C14ORF1 chromosome 14 open reading frame 1
C3 complement component 3
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC132 coiled-coil domain containing 132
CD58 CD58 molecule
CD86 CD86 molecule
CDY1 chromodomain protein, Y-linked, 1
CEP295 centrosomal protein 295kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHIA chitinase, acidic
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL7A1 collagen, type VII, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPF3 D4, zinc and double PHD fingers, family 3
DRD2 dopamine receptor D2
EBF2 early B-cell factor 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFNB3 ephrin-B3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
ELOVL2 ELOVL fatty acid elongase 2
ERC2 ELKS/RAB6-interacting/CAST family member 2
FAM105A family with sequence similarity 105, member A
GAL3ST4 galactose-3-O-sulfotransferase 4
GIP gastric inhibitory polypeptide
GLYAT glycine-N-acyltransferase
GMPR guanosine monophosphate reductase
GPR17 G protein-coupled receptor 17
GRM3 glutamate receptor, metabotropic 3
HIST1H4H histone cluster 1, H4h
HOXB1 homeobox B1
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IHH indian hedgehog
IL12B interleukin 12B
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA7 integrin, alpha 7
ITGB8 integrin, beta 8
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLHL22 kelch-like family member 22
LAT2 linker for activation of T cells family, member 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LINC00652 long intergenic non-protein coding RNA 652
LY86 lymphocyte antigen 86
MED16 mediator complex subunit 16
MLANA melan-A
MORC1 MORC family CW-type zinc finger 1
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
OLFM1 olfactomedin 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PCDHA5 protocadherin alpha 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLCH2 phospholipase C, eta 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKCI protein kinase C, iota
PRSS22 protease, serine, 22
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RARG retinoic acid receptor, gamma
RIN3 Ras and Rab interactor 3
RPL35A ribosomal protein L35a
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC38A7 solute carrier family 38, member 7
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLMO1 slowmo homolog 1 (Drosophila)
SYNJ1 synaptojanin 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBD thrombomodulin
TRIM31 tripartite motif containing 31
TUBA4B tubulin, alpha 4b
VIPR2 vasoactive intestinal peptide receptor 2
WNK1 WNK lysine deficient protein kinase 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB18 zinc finger and BTB domain containing 18
ZFHX2 zinc finger homeobox 2
ZNF235 zinc finger protein 235
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
AGMAT agmatine ureohydrolase (agmatinase)
AHDC1 AT hook, DNA binding motif, containing 1
ALOX12 arachidonate 12-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
BMP15 bone morphogenetic protein 15
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CLEC2B C-type lectin domain family 2, member B
CNGB3 cyclic nucleotide gated channel beta 3
CRMP1 collapsin response mediator protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUEDC1 CUE domain containing 1
CYB5R2 cytochrome b5 reductase 2
DAGLA diacylglycerol lipase, alpha
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNB1 ephrin-B1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPN1 epsin 1
FAM184A family with sequence similarity 184, member A
FBXO2 F-box protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLT4 fms-related tyrosine kinase 4
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GPR1 G protein-coupled receptor 1
GPR85 G protein-coupled receptor 85
HDAC7 histone deacetylase 7
HIST1H2AI histone cluster 1, H2ai
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL7 interleukin 7
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
KIAA1549L KIAA1549-like
KIRREL kin of IRRE like (Drosophila)
KRT33A keratin 33A, type I
LATS1 large tumor suppressor kinase 1
LINC00260 long intergenic non-protein coding RNA 260
LMCD1 LIM and cysteine-rich domains 1
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP3K7CL MAP3K7 C-terminal like
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MXD3 MAX dimerization protein 3
NIPAL2 NIPA-like domain containing 2
NTSR1 neurotensin receptor 1 (high affinity)
OSBP2 oxysterol binding protein 2
OVGP1 oviductal glycoprotein 1, 120kDa
PALMD palmdelphin
PARD6A par-6 family cell polarity regulator alpha
PIP prolactin-induced protein
PLCD1 phospholipase C, delta 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRB3 proline-rich protein BstNI subfamily 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPP25 ribonuclease P/MRP 25kDa subunit
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RWDD2A RWD domain containing 2A
SCGB2A2 secretoglobin, family 2A, member 2
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLAMF7 SLAM family member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMR3A submaxillary gland androgen regulated protein 3A
STAC SH3 and cysteine rich domain
STEAP4 STEAP family member 4
TEP1 telomerase-associated protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TMEM53 transmembrane protein 53
USP20 ubiquitin specific peptidase 20
WDR33 WD repeat domain 33
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF268 zinc finger protein 268
ZNF37BP zinc finger protein 37B, pseudogene
ZNF667 zinc finger protein 667
ZNHIT2 zinc finger, HIT-type containing 2