| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the cefotetan-4116 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ACTN2 | actinin, alpha 2 |
| ADM | adrenomedullin |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARHGAP25 | Rho GTPase activating protein 25 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BTNL3 | butyrophilin-like 3 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C4BPA | complement component 4 binding protein, alpha |
| CA1 | carbonic anhydrase I |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALB1 | calbindin 1, 28kDa |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCDC33 | coiled-coil domain containing 33 |
| CDON | cell adhesion associated, oncogene regulated |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLDN11 | claudin 11 |
| CLEC1A | C-type lectin domain family 1, member A |
| COL13A1 | collagen, type XIII, alpha 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRISP1 | cysteine-rich secretory protein 1 |
| CRYAB | crystallin, alpha B |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| CTSS | cathepsin S |
| DFNB31 | deafness, autosomal recessive 31 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| FAM13A | family with sequence similarity 13, member A |
| FAM66D | family with sequence similarity 66, member D |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FLJ11292 | |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GYPB | glycophorin B (MNS blood group) |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXB5 | homeobox B5 |
| HP | haptoglobin |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL2 | interleukin 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| LEFTY2 | left-right determination factor 2 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LST1 | leukocyte specific transcript 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MR1 | major histocompatibility complex, class I-related |
| MTMR7 | myotubularin related protein 7 |
| MYF6 | myogenic factor 6 (herculin) |
| MYL10 | myosin, light chain 10, regulatory |
| MYO15B | myosin XVB |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NEUROD2 | neuronal differentiation 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PMEL | premelanosome protein |
| PODNL1 | podocan-like 1 |
| PRX | periaxin |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RAP1GAP | RAP1 GTPase activating protein |
| RECQL5 | RecQ protein-like 5 |
| RFPL2 | ret finger protein-like 2 |
| RHO | rhodopsin |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RUNX1 | runt-related transcription factor 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPON1 | spondin 1, extracellular matrix protein |
| SSPN | sarcospan |
| TCP10L | t-complex 10-like |
| TENM1 | teneurin transmembrane protein 1 |
| TMEM212 | transmembrane protein 212 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TP63 | tumor protein p63 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CARF | calcium responsive transcription factor |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCS | copper chaperone for superoxide dismutase |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD83 | CD83 molecule |
| CES3 | carboxylesterase 3 |
| CFHR4 | complement factor H-related 4 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN4 | claudin 4 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DYSF | dysferlin |
| EGFL7 | EGF-like-domain, multiple 7 |
| FAM110B | family with sequence similarity 110, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GPX2 | glutathione peroxidase 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4A | histone cluster 1, H4a |
| HOXC8 | homeobox C8 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL21 | kelch-like family member 21 |
| KRT17 | keratin 17, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MDM4 | MDM4, p53 regulator |
| MITF | microphthalmia-associated transcription factor |
| MT1H | metallothionein 1H |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NLRX1 | NLR family member X1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPY4R | neuropeptide Y receptor Y4 |
| NRSN2 | neurensin 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| RAB3D | RAB3D, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RHBDD3 | rhomboid domain containing 3 |
| RUNDC3B | RUN domain containing 3B |
| S100A2 | S100 calcium binding protein A2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SNTA1 | syntrophin, alpha 1 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SSFA2 | sperm specific antigen 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBX19 | T-box 19 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR18 | WD repeat domain 18 |
| ZNF696 | zinc finger protein 696 |
| ZNF813 | zinc finger protein 813 |
| ZNF816 | zinc finger protein 816 |
