| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cefotiam-2458 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACVR1B | activin A receptor, type IB |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ATP13A2 | ATPase type 13A2 |
| ATXN2L | ataxin 2-like |
| AURKA | aurora kinase A |
| BCL2L1 | BCL2-like 1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC71 | coiled-coil domain containing 71 |
| CDC14A | cell division cycle 14A |
| CDC25C | cell division cycle 25C |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSPP | dentin sialophosphoprotein |
| ECE1 | endothelin converting enzyme 1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EWSR1 | EWS RNA-binding protein 1 |
| EXOC5 | exocyst complex component 5 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FCMR | Fc fragment of IgM receptor |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR153 | G protein-coupled receptor 153 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HN1L | hematological and neurological expressed 1-like |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGHM | immunoglobulin heavy constant mu |
| IQCE | IQ motif containing E |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| LEFTY1 | left-right determination factor 1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBTD1 | mbt domain containing 1 |
| MCAM | melanoma cell adhesion molecule |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MYL10 | myosin, light chain 10, regulatory |
| MYOZ2 | myozenin 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NEK9 | NIMA-related kinase 9 |
| NOX1 | NADPH oxidase 1 |
| NUP160 | nucleoporin 160kDa |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| OMD | osteomodulin |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PLCD1 | phospholipase C, delta 1 |
| PLK4 | polo-like kinase 4 |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| RAB6A | RAB6A, member RAS oncogene family |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPGRIP1L | RPGRIP1-like |
| RPH3A | rabphilin 3A |
| RPL10L | ribosomal protein L10-like |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RXRB | retinoid X receptor, beta |
| SC5D | sterol-C5-desaturase |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD5 | SMAD family member 5 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STAB1 | stabilin 1 |
| TAC3 | tachykinin 3 |
| TNS1 | tensin 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VGF | VGF nerve growth factor inducible |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| AMPH | amphiphysin |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARSB | arylsulfatase B |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBX7 | chromobox homolog 7 |
| CCDC132 | coiled-coil domain containing 132 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIC | capicua transcriptional repressor |
| CNTLN | centlein, centrosomal protein |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| EPHB6 | EPH receptor B6 |
| ERCC4 | excision repair cross-complementation group 4 |
| FCHO1 | FCH domain only 1 |
| FKBP5 | FK506 binding protein 5 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FZD4 | frizzled class receptor 4 |
| GK2 | glycerol kinase 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR15 | G protein-coupled receptor 15 |
| GPX2 | glutathione peroxidase 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| IHH | indian hedgehog |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IQCC | IQ motif containing C |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KLHL36 | kelch-like family member 36 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LOC729164 | hCG1732469 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPK10 | mitogen-activated protein kinase 10 |
| MCC | mutated in colorectal cancers |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MDM4 | MDM4, p53 regulator |
| MMP3 | matrix metallopeptidase 3 |
| MYOZ1 | myozenin 1 |
| NEUROD4 | neuronal differentiation 4 |
| NPY4R | neuropeptide Y receptor Y4 |
| NXPH4 | neurexophilin 4 |
| PDE12 | phosphodiesterase 12 |
| PGP | phosphoglycolate phosphatase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PODXL2 | podocalyxin-like 2 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRR14L | proline rich 14-like |
| PRSS53 | protease, serine, 53 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| REC8 | REC8 meiotic recombination protein |
| RNF2 | ring finger protein 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STX1A | syntaxin 1A (brain) |
| TCTN2 | tectonic family member 2 |
| TMC5 | transmembrane channel-like 5 |
| TMEM209 | transmembrane protein 209 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TSPYL2 | TSPY-like 2 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VNN2 | vanin 2 |
| VPS9D1 | VPS9 domain containing 1 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF219 | zinc finger protein 219 |
| ZNF276 | zinc finger protein 276 |
| ZNF345 | zinc finger protein 345 |
