cefsulodin-2988 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cefsulodin-2988 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AHCYL2 adenosylhomocysteinase-like 2
AK1 adenylate kinase 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANG angiogenin, ribonuclease, RNase A family, 5
AOC3 amine oxidase, copper containing 3
APOD apolipoprotein D
AREG amphiregulin
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASB1 ankyrin repeat and SOCS box containing 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CA6 carbonic anhydrase VI
CD300C CD300c molecule
CD7 CD7 molecule
CEP170B centrosomal protein 170B
CIITA class II, major histocompatibility complex, transactivator
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRMP1 collapsin response mediator protein 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNM3 dynamin 3
DNMBP dynamin binding protein
DOCK5 dedicator of cytokinesis 5
EN1 engrailed homeobox 1
ENDOD1 endonuclease domain containing 1
EPHA7 EPH receptor A7
FAM105A family with sequence similarity 105, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FDPS farnesyl diphosphate synthase
FHL1 four and a half LIM domains 1
FJX1 four jointed box 1 (Drosophila)
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GLE1 GLE1 RNA export mediator
GLRX3 glutaredoxin 3
GPM6B glycoprotein M6B
GRAMD1B GRAM domain containing 1B
GVINP1 GTPase, very large interferon inducible pseudogene 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2AL histone cluster 1, H2al
IAPP islet amyloid polypeptide
ICOSLG inducible T-cell co-stimulator ligand
IGFBP6 insulin-like growth factor binding protein 6
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL19 interleukin 19
JAG1 jagged 1
KRT23 keratin 23, type I
LAMP1 lysosomal-associated membrane protein 1
LEP leptin
LIMD1 LIM domains containing 1
LIMD2 LIM domain containing 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MCAM melanoma cell adhesion molecule
MFAP3L microfibrillar-associated protein 3-like
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MST1 macrophage stimulating 1
MVP major vault protein
MYLK myosin light chain kinase
NCR2 natural cytotoxicity triggering receptor 2
NF2 neurofibromin 2 (merlin)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
ONECUT2 one cut homeobox 2
OVOL2 ovo-like zinc finger 2
PCDH11Y protocadherin 11 Y-linked
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PLCH1 phospholipase C, eta 1
PNMAL1 paraneoplastic Ma antigen family-like 1
PNPLA4 patatin-like phospholipase domain containing 4
POU1F1 POU class 1 homeobox 1
PRICKLE3 prickle homolog 3 (Drosophila)
PROL1 proline rich, lacrimal 1
PTGDR2 prostaglandin D2 receptor 2
PTGES prostaglandin E synthase
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
S100A11 S100 calcium binding protein A11
S100A12 S100 calcium binding protein A12
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SETBP1 SET binding protein 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SNX13 sorting nexin 13
SPHK2 sphingosine kinase 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TACR1 tachykinin receptor 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM144 transmembrane protein 144
TSC2 tuberous sclerosis 2
WIZ widely interspaced zinc finger motifs
ZBTB20 zinc finger and BTB domain containing 20
ZNF280B zinc finger protein 280B
ZNF75D zinc finger protein 75D
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASAP1-IT1 ASAP1 intronic transcript 1
ATAT1 alpha tubulin acetyltransferase 1
BNC2 basonuclin 2
C17ORF70 chromosome 17 open reading frame 70
C3ORF14 chromosome 3 open reading frame 14
C3ORF18 chromosome 3 open reading frame 18
CABP2 calcium binding protein 2
CCDC85C coiled-coil domain containing 85C
CCRL2 chemokine (C-C motif) receptor-like 2
CDHR2 cadherin-related family member 2
CDR2L cerebellar degeneration-related protein 2-like
CENPO centromere protein O
CFAP69 cilia and flagella associated protein 69
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLGN calmegin
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRYGC crystallin, gamma C
CST1 cystatin SN
CTAGE9 CTAGE family, member 9
DSPP dentin sialophosphoprotein
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM13C family with sequence similarity 13, member C
FBXL6 F-box and leucine-rich repeat protein 6
FBXW4 F-box and WD repeat domain containing 4
FHIT fragile histidine triad
FHL3 four and a half LIM domains 3
FMO4 flavin containing monooxygenase 4
GLRA1 glycine receptor, alpha 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA2 homeobox A2
HOXC10 homeobox C10
IFNA14 interferon, alpha 14
IGFLR1 IGF-like family receptor 1
IGH immunoglobulin heavy locus
INO80D INO80 complex subunit D
IPO4 importin 4
JPH3 junctophilin 3
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KIAA0319L KIAA0319-like
KIF1B kinesin family member 1B
KLHL36 kelch-like family member 36
KLK11 kallikrein-related peptidase 11
LINC00260 long intergenic non-protein coding RNA 260
LY6D lymphocyte antigen 6 complex, locus D
MAP6D1 MAP6 domain containing 1
MRPS18C mitochondrial ribosomal protein S18C
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NLGN1 neuroligin 1
NMUR1 neuromedin U receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPPB natriuretic peptide B
NSUN6 NOP2/Sun domain family, member 6
NT5DC3 5'-nucleotidase domain containing 3
OCA2 oculocutaneous albinism II
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCBP4 poly(rC) binding protein 4
PIPOX pipecolic acid oxidase
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POR P450 (cytochrome) oxidoreductase
PRF1 perforin 1 (pore forming protein)
PRR7 proline rich 7 (synaptic)
PRSS53 protease, serine, 53
PYGB phosphorylase, glycogen; brain
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCRT1 scratch family zinc finger 1
SH2D4A SH2 domain containing 4A
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STATH statherin
TCHH trichohyalin
TESK1 testis-specific kinase 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF3 transmembrane 7 superfamily member 3
TNNT1 troponin T type 1 (skeletal, slow)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
WASF3 WAS protein family, member 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF385D zinc finger protein 385D
ZNF484 zinc finger protein 484
ZNF747 zinc finger protein 747
ZNF81 zinc finger protein 81
ZXDB zinc finger, X-linked, duplicated B