cefsulodin-4067 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the cefsulodin-4067 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKH ANKH inorganic pyrophosphate transport regulator
APOC4 apolipoprotein C-IV
APP amyloid beta (A4) precursor protein
ARSA arylsulfatase A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL6 B-cell CLL/lymphoma 6
BGN biglycan
BTNL2 butyrophilin-like 2
C14ORF79 chromosome 14 open reading frame 79
C19ORF26 chromosome 19 open reading frame 26
CA1 carbonic anhydrase I
CACFD1 calcium channel flower domain containing 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD53 CD53 molecule
CDC42 cell division cycle 42
CDH5 cadherin 5, type 2 (vascular endothelium)
COMMD4 COMM domain containing 4
CSF1R colony stimulating factor 1 receptor
CT62 cancer/testis antigen 62
CTNND2 catenin (cadherin-associated protein), delta 2
CTSS cathepsin S
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYTH3 cytohesin 3
DNAI2 dynein, axonemal, intermediate chain 2
DPF1 D4, zinc and double PHD fingers family 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ETV1 ets variant 1
FABP7 fatty acid binding protein 7, brain
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLYAT glycine-N-acyltransferase
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSPT1 G1 to S phase transition 1
GYG2 glycogenin 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXB7 homeobox B7
HOXD10 homeobox D10
HSF1 heat shock transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFFO1 intermediate filament family orphan 1
IL1RN interleukin 1 receptor antagonist
ING4 inhibitor of growth family, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KRT24 keratin 24, type I
LINC00652 long intergenic non-protein coding RNA 652
LIPE lipase, hormone-sensitive
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MARK1 MAP/microtubule affinity-regulating kinase 1
MMP25 matrix metallopeptidase 25
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSX2 msh homeobox 2
NF1 neurofibromin 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
PCDH11Y protocadherin 11 Y-linked
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PEX3 peroxisomal biogenesis factor 3
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIPOX pipecolic acid oxidase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
PRSS8 protease, serine, 8
PRTN3 proteinase 3
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRJ protein tyrosine phosphatase, receptor type, J
PYY peptide YY
RBMS3 RNA binding motif, single stranded interacting protein 3
RIMS2 regulating synaptic membrane exocytosis 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF122 ring finger protein 122
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPAG6 sperm associated antigen 6
SPHK2 sphingosine kinase 2
ST7L suppression of tumorigenicity 7 like
STAB1 stabilin 1
SUGP1 SURP and G patch domain containing 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNGR1 synaptogyrin 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCF3 transcription factor 3
TEX261 testis expressed 261
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TSHR thyroid stimulating hormone receptor
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
VAV3 vav 3 guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
VGLL3 vestigial-like family member 3
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZNF334 zinc finger protein 334

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ANP32A-IT1 ANP32A intronic transcript 1
ANXA10 annexin A10
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP22 Rho GTPase activating protein 22
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BAHCC1 BAH domain and coiled-coil containing 1
BAX BCL2-associated X protein
BDKRB1 bradykinin receptor B1
BMP15 bone morphogenetic protein 15
C11ORF30 chromosome 11 open reading frame 30
C14ORF105 chromosome 14 open reading frame 105
C3AR1 complement component 3a receptor 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC2B C-type lectin domain family 2, member B
CNTFR ciliary neurotrophic factor receptor
CORO1A coronin, actin binding protein, 1A
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYBRD1 cytochrome b reductase 1
DBF4B DBF4 zinc finger B
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAH17 dynein, axonemal, heavy chain 17
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
EYA3 EYA transcriptional coactivator and phosphatase 3
EYA4 EYA transcriptional coactivator and phosphatase 4
FBRS fibrosin
FBXO46 F-box protein 46
GPC3 glypican 3
GPR19 G protein-coupled receptor 19
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H2BN histone cluster 1, H2bn
HOOK1 hook microtubule-tethering protein 1
HOXC4 homeobox C4
IFT140 intraflagellar transport 140
KLF13 Kruppel-like factor 13
KRT86 keratin 86, type II
LIME1 Lck interacting transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC2 leucine rich repeat containing 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAL mal, T-cell differentiation protein
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NOTCH1 notch 1
NPVF neuropeptide VF precursor
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBP2 oxysterol binding protein 2
PBOV1 prostate and breast cancer overexpressed 1
PCDHA5 protocadherin alpha 5
PIDD1 p53-induced death domain protein 1
PLBD1 phospholipase B domain containing 1
PPL periplakin
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS53 protease, serine, 53
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40A RAB40A, member RAS oncogene family
RAI2 retinoic acid induced 2
RFPL3 ret finger protein-like 3
RPGRIP1L RPGRIP1-like
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A8 solute carrier family 12, member 8
SLC16A6 solute carrier family 16, member 6
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPRYD7 SPRY domain containing 7
SSTR4 somatostatin receptor 4
THRB thyroid hormone receptor, beta
TIGD6 tigger transposable element derived 6
TMEM8B transmembrane protein 8B
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TPRA1 transmembrane protein, adipocyte asscociated 1
USP19 ubiquitin specific peptidase 19
VGF VGF nerve growth factor inducible
ZBTB22 zinc finger and BTB domain containing 22
ZNF669 zinc finger protein 669
ZNF747 zinc finger protein 747