ceftazidime-1721 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ceftazidime-1721 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABHD3 abhydrolase domain containing 3
AMT aminomethyltransferase
AP3D1 adaptor-related protein complex 3, delta 1 subunit
BMP15 bone morphogenetic protein 15
BPHL biphenyl hydrolase-like (serine hydrolase)
C2ORF27A chromosome 2 open reading frame 27A
C4BPA complement component 4 binding protein, alpha
CAMK1G calcium/calmodulin-dependent protein kinase IG
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDIP1 cell death-inducing p53 target 1
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CRAT carnitine O-acetyltransferase
CRYM crystallin, mu
CSNK1D casein kinase 1, delta
CXCR3 chemokine (C-X-C motif) receptor 3
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPYSL4 dihydropyrimidinase-like 4
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
E2F1 E2F transcription factor 1
EFNB3 ephrin-B3
FBLN1 fibulin 1
FBP1 fructose-1,6-bisphosphatase 1
FH fumarate hydratase
FLOT1 flotillin 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GJD2 gap junction protein, delta 2, 36kDa
GPR107 G protein-coupled receptor 107
GPR21 G protein-coupled receptor 21
GPSM2 G-protein signaling modulator 2
GUCA1B guanylate cyclase activator 1B (retina)
HDAC5 histone deacetylase 5
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HOXA5 homeobox A5
IFT27 intraflagellar transport 27
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL27RA interleukin 27 receptor, alpha
INTS1 integrator complex subunit 1
ITGB5 integrin, beta 5
JAG2 jagged 2
KLK5 kallikrein-related peptidase 5
KYNU kynureninase
LRRC41 leucine rich repeat containing 41
MANEA mannosidase, endo-alpha
MMP25 matrix metallopeptidase 25
MPI mannose phosphate isomerase
MXRA8 matrix-remodelling associated 8
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXT2 nuclear transport factor 2-like export factor 2
OPRL1 opiate receptor-like 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PARD3 par-3 family cell polarity regulator
PCGF2 polycomb group ring finger 2
PEX1 peroxisomal biogenesis factor 1
PIAS4 protein inhibitor of activated STAT, 4
PLIN2 perilipin 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRPH2 peripherin 2 (retinal degeneration, slow)
RAB4B RAB4B, member RAS oncogene family
RHOT2 ras homolog family member T2
RNASE6 ribonuclease, RNase A family, k6
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
S1PR4 sphingosine-1-phosphate receptor 4
SCARB2 scavenger receptor class B, member 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERBP1 SERPINE1 mRNA binding protein 1
SGSH N-sulfoglucosamine sulfohydrolase
SIGLEC7 sialic acid binding Ig-like lectin 7
SMAD3 SMAD family member 3
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
STK25 serine/threonine kinase 25
STRN striatin, calmodulin binding protein
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
TDRKH tudor and KH domain containing
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TOX4 TOX high mobility group box family member 4
TRAF1 TNF receptor-associated factor 1
TRIB2 tribbles pseudokinase 2
TRIL TLR4 interactor with leucine-rich repeats
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBE2D2 ubiquitin-conjugating enzyme E2D 2
USB1 U6 snRNA biogenesis 1
USP34 ubiquitin specific peptidase 34
VARS valyl-tRNA synthetase
WDTC1 WD and tetratricopeptide repeats 1
YIPF4 Yip1 domain family, member 4
ZMYND8 zinc finger, MYND-type containing 8
ZNF32 zinc finger protein 32

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACTL6A actin-like 6A
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATG4A autophagy related 4A, cysteine peptidase
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
C14ORF159 chromosome 14 open reading frame 159
C8ORF44 chromosome 8 open reading frame 44
CASD1 CAS1 domain containing 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDK8 cyclin-dependent kinase 8
CHMP1A charged multivesicular body protein 1A
CLASRP CLK4-associating serine/arginine rich protein
CLCN6 chloride channel, voltage-sensitive 6
CLDN15 claudin 15
CTSG cathepsin G
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAAM1 dishevelled associated activator of morphogenesis 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DAZAP1 DAZ associated protein 1
DDA1 DET1 and DDB1 associated 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAAF2 dynein, axonemal, assembly factor 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EVL Enah/Vasp-like
FADS2 fatty acid desaturase 2
FAM172A family with sequence similarity 172, member A
FGL1 fibrinogen-like 1
FMNL1 formin-like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GATAD2A GATA zinc finger domain containing 2A
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GSK3A glycogen synthase kinase 3 alpha
GSTA4 glutathione S-transferase alpha 4
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HCAR3 hydroxycarboxylic acid receptor 3
HINFP histone H4 transcription factor
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IL4R interleukin 4 receptor
IPO4 importin 4
KIAA1598
KIF18B kinesin family member 18B
LAGE3 L antigen family, member 3
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LSM1 LSM1, U6 small nuclear RNA associated
MAGOHB mago-nashi homolog B (Drosophila)
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
METAP1 methionyl aminopeptidase 1
MFSD12 major facilitator superfamily domain containing 12
MPV17 MpV17 mitochondrial inner membrane protein
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NOP10 NOP10 ribonucleoprotein
NT5E 5'-nucleotidase, ecto (CD73)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OCEL1 occludin/ELL domain containing 1
PAQR3 progestin and adipoQ receptor family member III
PFDN1 prefoldin subunit 1
PHYH phytanoyl-CoA 2-hydroxylase
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLA2G12A phospholipase A2, group XIIA
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRR14L proline rich 14-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SAC3D1 SAC3 domain containing 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEPW1 selenoprotein W, 1
SERTAD3 SERTA domain containing 3
SH3GL1 SH3-domain GRB2-like 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLMO2 slowmo homolog 2 (Drosophila)
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
STYXL1 serine/threonine/tyrosine interacting-like 1
SUN2 Sad1 and UNC84 domain containing 2
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TBL3 transducin (beta)-like 3
TMPRSS6 transmembrane protease, serine 6
TOR4A torsin family 4, member A
TRIM22 tripartite motif containing 22
TUBA4B tubulin, alpha 4b
TULP4 tubby like protein 4
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBL4A ubiquitin-like 4A
ZBTB48 zinc finger and BTB domain containing 48
ZIM2 zinc finger, imprinted 2
ZNF140 zinc finger protein 140
ZNF175 zinc finger protein 175
ZNF263 zinc finger protein 263
ZNF280D zinc finger protein 280D
ZNF350 zinc finger protein 350
ZNF468 zinc finger protein 468