ceftazidime-5054 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ceftazidime-5054 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRB2 adhesion G protein-coupled receptor B2
ADGRL3 adhesion G protein-coupled receptor L3
AKAP8L A kinase (PRKA) anchor protein 8-like
ANGPTL2 angiopoietin-like 2
APAF1 apoptotic peptidase activating factor 1
ARHGAP35 Rho GTPase activating protein 35
ARHGAP44 Rho GTPase activating protein 44
ATF7IP activating transcription factor 7 interacting protein
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C20ORF195 chromosome 20 open reading frame 195
C2ORF72 chromosome 2 open reading frame 72
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CD58 CD58 molecule
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
DBT dihydrolipoamide branched chain transacylase E2
DCN decorin
DICER1 dicer 1, ribonuclease type III
DMBT1 deleted in malignant brain tumors 1
DMC1 DNA meiotic recombinase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
FAM46C family with sequence similarity 46, member C
FAM49B family with sequence similarity 49, member B
FOXP3 forkhead box P3
FUS FUS RNA binding protein
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GDF5 growth differentiation factor 5
GPR17 G protein-coupled receptor 17
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HBB hemoglobin, beta
HDAC7 histone deacetylase 7
HES2 hes family bHLH transcription factor 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IFITM1 interferon induced transmembrane protein 1
IL17RB interleukin 17 receptor B
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD14 potassium channel tetramerization domain containing 14
KDM4B lysine (K)-specific demethylase 4B
KYNU kynureninase
LDB2 LIM domain binding 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00115 long intergenic non-protein coding RNA 115
LINC00597 long intergenic non-protein coding RNA 597
LY86 lymphocyte antigen 86
MAL mal, T-cell differentiation protein
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MATN3 matrilin 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MERTK MER proto-oncogene, tyrosine kinase
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MUC1 mucin 1, cell surface associated
NOTCH3 notch 3
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NUMA1 nuclear mitotic apparatus protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PILRA paired immunoglobin-like type 2 receptor alpha
POGZ pogo transposable element with ZNF domain
POM121 POM121 transmembrane nucleoporin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCN11A sodium channel, voltage gated, type XI alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SGSM2 small G protein signaling modulator 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLN sarcolipin
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOX10 SRY (sex determining region Y)-box 10
SPEG SPEG complex locus
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TMPRSS2 transmembrane protease, serine 2
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TPSAB1 tryptase alpha/beta 1
TSPAN2 tetraspanin 2
USP6 ubiquitin specific peptidase 6
VSNL1 visinin-like 1
WNK1 WNK lysine deficient protein kinase 1
XIST X inactive specific transcript (non-protein coding)
ZNF280B zinc finger protein 280B
ZNF528 zinc finger protein 528
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADCY6 adenylate cyclase 6
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AURKC aurora kinase C
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
B9D2 B9 protein domain 2
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
CAPN15 calpain 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD70 CD70 molecule
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CFAP44 cilia and flagella associated protein 44
CFAP45 cilia and flagella associated protein 45
CHRDL1 chordin-like 1
CIDEC cell death-inducing DFFA-like effector c
CLK1 CDC-like kinase 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPNE7 copine VII
CRY2 cryptochrome circadian clock 2
CRYBA2 crystallin, beta A2
CTSF cathepsin F
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
EGF epidermal growth factor
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FKBP10 FK506 binding protein 10, 65 kDa
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GPC3 glypican 3
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HIST1H2BN histone cluster 1, H2bn
HIST1H3A histone cluster 1, H3a
HOXA4 homeobox A4
IL22 interleukin 22
IRF9 interferon regulatory factor 9
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0355 KIAA0355
KRT34 keratin 34, type I
LAX1 lymphocyte transmembrane adaptor 1
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRK1 leucine-rich repeat kinase 1
MUC3B mucin 3B, cell surface associated
MUM1 melanoma associated antigen (mutated) 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
PACS1 phosphofurin acidic cluster sorting protein 1
PER3 period circadian clock 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PPT2 palmitoyl-protein thioesterase 2
PRKCE protein kinase C, epsilon
PRKG2 protein kinase, cGMP-dependent, type II
PRR15L proline rich 15-like
PRSS16 protease, serine, 16 (thymus)
PSKH1 protein serine kinase H1
RNF121 ring finger protein 121
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SRD5A3 steroid 5 alpha-reductase 3
STRA6 stimulated by retinoic acid 6
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBXAS1 thromboxane A synthase 1 (platelet)
TMEM159 transmembrane protein 159
TMEM180 transmembrane protein 180
TMEM8B transmembrane protein 8B
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
ULBP2 UL16 binding protein 2
WDR91 WD repeat domain 91
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF551 zinc finger protein 551
ZNF862 zinc finger protein 862