ceftazidime Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A cephalosporin bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. (Chemical Entities of Biological Interest Ontology, CHEBI_3508)
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Genes

6 genes differentially expressed following the ceftazidime small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
USP6NL USP6 N-terminal like 4.36685
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 3.21579
RUVBL1 RuvB-like AAA ATPase 1 3.11873
ZSCAN18 zinc finger and SCAN domain containing 18 3.11266

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -3.72216
MFSD12 major facilitator superfamily domain containing 12 -3.19235