cefuroxime-2526 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the cefuroxime-2526 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTN2 actinin, alpha 2
ADH6 alcohol dehydrogenase 6 (class V)
AEN apoptosis enhancing nuclease
ANTXR1 anthrax toxin receptor 1
ATP10B ATPase, class V, type 10B
ATP7B ATPase, Cu++ transporting, beta polypeptide
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C22ORF24 chromosome 22 open reading frame 24
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC71 coiled-coil domain containing 71
CENPO centromere protein O
CEP295 centrosomal protein 295kDa
CFAP69 cilia and flagella associated protein 69
CHN2 chimerin 2
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL6A1 collagen, type VI, alpha 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNPEP aspartyl aminopeptidase
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
E2F5 E2F transcription factor 5, p130-binding
EBF2 early B-cell factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EXTL3 exostosin-like glycosyltransferase 3
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FBP1 fructose-1,6-bisphosphatase 1
FLJ11292
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPR35 G protein-coupled receptor 35
GRM8 glutamate receptor, metabotropic 8
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HGD homogentisate 1,2-dioxygenase
HIST1H2AL histone cluster 1, H2al
HOXD13 homeobox D13
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICAM1 intercellular adhesion molecule 1
IL36RN interleukin 36 receptor antagonist
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF25 kinesin family member 25
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KLK6 kallikrein-related peptidase 6
KYNU kynureninase
LAMC3 laminin, gamma 3
LRRN2 leucine rich repeat neuronal 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MFSD7 major facilitator superfamily domain containing 7
MMP3 matrix metallopeptidase 3
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
NCAM1 neural cell adhesion molecule 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDLIM4 PDZ and LIM domain 4
PEG10 paternally expressed 10
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLXNB3 plexin B3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRR16 proline rich 16
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PXDN peroxidasin
RASA3 RAS p21 protein activator 3
REC8 REC8 meiotic recombination protein
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RTP4 receptor (chemosensory) transporter protein 4
RUFY3 RUN and FYVE domain containing 3
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SH2D3A SH2 domain containing 3A
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMCP sperm mitochondria-associated cysteine-rich protein
STMN3 stathmin-like 3
TAPBP TAP binding protein (tapasin)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCP11L1 t-complex 11, testis-specific-like 1
TFR2 transferrin receptor 2
TIMELESS timeless circadian clock
TLDC1 TBC/LysM-associated domain containing 1
TPMT thiopurine S-methyltransferase
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
VSNL1 visinin-like 1
WDR78 WD repeat domain 78
WNT2B wingless-type MMTV integration site family, member 2B
ZFP64 ZFP64 zinc finger protein
ZNF155 zinc finger protein 155

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM15 ADAM metallopeptidase domain 15
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
ANO10 anoctamin 10
ANXA3 annexin A3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOH apolipoprotein H (beta-2-glycoprotein I)
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARRB1 arrestin, beta 1
ASPN asporin
BAG4 BCL2-associated athanogene 4
BAMBI BMP and activin membrane-bound inhibitor
BLVRB biliverdin reductase B
CCDC106 coiled-coil domain containing 106
CCL20 chemokine (C-C motif) ligand 20
CDK20 cyclin-dependent kinase 20
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHML choroideremia-like (Rab escort protein 2)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLEC7A C-type lectin domain family 7, member A
COQ6 coenzyme Q6 monooxygenase
CROT carnitine O-octanoyltransferase
CTRL chymotrypsin-like
CTSO cathepsin O
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DKK2 dickkopf WNT signaling pathway inhibitor 2
DYM dymeclin
EPHB6 EPH receptor B6
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXL15 F-box and leucine-rich repeat protein 15
FIP1L1 factor interacting with PAPOLA and CPSF1
FLT4 fms-related tyrosine kinase 4
GALK1 galactokinase 1
GLTP glycolipid transfer protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HP haptoglobin
ICK intestinal cell (MAK-like) kinase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
IPO8 importin 8
JUP junction plakoglobin
KIAA0753 KIAA0753
KLHL36 kelch-like family member 36
METRN meteorin, glial cell differentiation regulator
METTL21B methyltransferase like 21B
MYO5C myosin VC
NACA2 nascent polypeptide-associated complex alpha subunit 2
NARFL nuclear prelamin A recognition factor-like
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NUMB numb homolog (Drosophila)
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGB5 protocadherin gamma subfamily B, 5
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PTX3 pentraxin 3, long
QPCT glutaminyl-peptide cyclotransferase
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBM47 RNA binding motif protein 47
RRAS related RAS viral (r-ras) oncogene homolog
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERINC5 serine incorporator 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIRAL2 SIR2 antiphage like 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMR3A submaxillary gland androgen regulated protein 3A
SPINT1 serine peptidase inhibitor, Kunitz type 1
STAT5A signal transducer and activator of transcription 5A
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAS2R10 taste receptor, type 2, member 10
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAPPC13 trafficking protein particle complex 13
TSPAN13 tetraspanin 13
TWISTNB TWIST neighbor
USB1 U6 snRNA biogenesis 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XAB2 XPA binding protein 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF552 zinc finger protein 552
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2