| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cefuroxime-6261 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AHI1 | Abelson helper integration site 1 |
| AIM1L | absent in melanoma 1-like |
| APP | amyloid beta (A4) precursor protein |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARSB | arylsulfatase B |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BMP4 | bone morphogenetic protein 4 |
| BMP6 | bone morphogenetic protein 6 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CD34 | CD34 molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| COL5A1 | collagen, type V, alpha 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CUL4B | cullin 4B |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DMTN | dematin actin binding protein |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPOR | erythropoietin receptor |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAS | Fas cell surface death receptor |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GK | glycerol kinase |
| GLG1 | golgi glycoprotein 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GSTP1 | glutathione S-transferase pi 1 |
| HOMER3 | homer scaffolding protein 3 |
| IL11 | interleukin 11 |
| IL27RA | interleukin 27 receptor, alpha |
| IL5RA | interleukin 5 receptor, alpha |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0355 | KIAA0355 |
| KIAA1107 | KIAA1107 |
| KLHL22 | kelch-like family member 22 |
| KRT17 | keratin 17, type I |
| LPIN2 | lipin 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MALT1 | MALT1 paracaspase |
| MAP4 | microtubule-associated protein 4 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MXD3 | MAX dimerization protein 3 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEUROD4 | neuronal differentiation 4 |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE8B | phosphodiesterase 8B |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLK3 | polo-like kinase 3 |
| PLK4 | polo-like kinase 4 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRSS53 | protease, serine, 53 |
| RAB6B | RAB6B, member RAS oncogene family |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| REST | RE1-silencing transcription factor |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF24 | ring finger protein 24 |
| SFXN3 | sideroflexin 3 |
| SH2D3A | SH2 domain containing 3A |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMC4 | structural maintenance of chromosomes 4 |
| SMTN | smoothelin |
| SP1 | Sp1 transcription factor |
| SRPX | sushi-repeat containing protein, X-linked |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| TADA3 | transcriptional adaptor 3 |
| TBX5 | T-box 5 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TRBC1 | T cell receptor beta constant 1 |
| TSPAN9 | tetraspanin 9 |
| USP34 | ubiquitin specific peptidase 34 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF277 | zinc finger protein 277 |
| ZNF286A | zinc finger protein 286A |
| Symbol | Name |
|---|---|
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ACTL8 | actin-like 8 |
| AEN | apoptosis enhancing nuclease |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BMP15 | bone morphogenetic protein 15 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN15 | calpain 15 |
| CEP72 | centrosomal protein 72kDa |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNM1 | dynamin 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVPL | envoplakin |
| F8 | coagulation factor VIII, procoagulant component |
| FPGS | folylpolyglutamate synthase |
| FUZ | fuzzy planar cell polarity protein |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GID4 | GID complex subunit 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| HIRA | histone cell cycle regulator |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL2 | interleukin 2 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF2 | interferon regulatory factor 2 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0894 | KIAA0894 protein |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MITF | microphthalmia-associated transcription factor |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARPBP | PARP1 binding protein |
| PDE12 | phosphodiesterase 12 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| PYGB | phosphorylase, glycogen; brain |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RCOR3 | REST corepressor 3 |
| RECQL4 | RecQ protein-like 4 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STXBP2 | syntaxin binding protein 2 |
| TEAD3 | TEA domain family member 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TXLNG | taxilin gamma |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBXN6 | UBX domain protein 6 |
| USP36 | ubiquitin specific peptidase 36 |
| WDR19 | WD repeat domain 19 |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF141 | zinc finger protein 141 |
| ZNF219 | zinc finger protein 219 |
| ZNF271P | zinc finger protein 271, pseudogene |
| ZNF280D | zinc finger protein 280D |
| ZNF442 | zinc finger protein 442 |
| ZNF623 | zinc finger protein 623 |
| ZNF668 | zinc finger protein 668 |
| ZNF767P | zinc finger family member 767, pseudogene |