celecoxib-206 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the celecoxib-206 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADAM22 ADAM metallopeptidase domain 22
AGGF1 angiogenic factor with G patch and FHA domains 1
ATM ATM serine/threonine kinase
BIN1 bridging integrator 1
BNC2 basonuclin 2
BRAP BRCA1 associated protein
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF76 chromosome 10 open reading frame 76
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMKV CaM kinase-like vesicle-associated
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CFLAR CASP8 and FADD-like apoptosis regulator
COL1A2 collagen, type I, alpha 2
COX5B cytochrome c oxidase subunit Vb
CRAT carnitine O-acetyltransferase
CRMP1 collapsin response mediator protein 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKD diacylglycerol kinase, delta 130kDa
DRD2 dopamine receptor D2
ECM1 extracellular matrix protein 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ERCC4 excision repair cross-complementation group 4
FAM107A family with sequence similarity 107, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FERMT1 fermitin family member 1
FKBP10 FK506 binding protein 10, 65 kDa
FOLR1 folate receptor 1 (adult)
FSCN3 fascin actin-bundling protein 3, testicular
GHRHR growth hormone releasing hormone receptor
GNAS GNAS complex locus
GOSR2 golgi SNAP receptor complex member 2
GPSM3 G-protein signaling modulator 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIST1H2BD histone cluster 1, H2bd
HLA-E major histocompatibility complex, class I, E
HOMER3 homer scaffolding protein 3
ICAM1 intercellular adhesion molecule 1
IL9R interleukin 9 receptor
KIAA0141 KIAA0141
KIF2A kinesin heavy chain member 2A
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KMT2A lysine (K)-specific methyltransferase 2A
LIME1 Lck interacting transmembrane adaptor 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTS1 leucine zipper, putative tumor suppressor 1
MAPK3 mitogen-activated protein kinase 3
MED31 mediator complex subunit 31
MFAP2 microfibrillar-associated protein 2
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MX2 MX dynamin-like GTPase 2
NIPAL2 NIPA-like domain containing 2
NRSN2 neurensin 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
ORC1 origin recognition complex, subunit 1
PAK1IP1 PAK1 interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PON3 paraoxonase 3
PRB1 proline-rich protein BstNI subfamily 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHO rhodopsin
RNF121 ring finger protein 121
RPL14 ribosomal protein L14
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SASH1 SAM and SH3 domain containing 1
SDC3 syndecan 3
SETD4 SET domain containing 4
SGSM3 small G protein signaling modulator 3
SIL1 SIL1 nucleotide exchange factor
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPEG SPEG complex locus
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYT2 synaptotagmin II
TADA2A transcriptional adaptor 2A
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCTN2 tectonic family member 2
TF transferrin
TMEM180 transmembrane protein 180
TMEM63A transmembrane protein 63A
TPSG1 tryptase gamma 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WRAP53 WD repeat containing, antisense to TP53
YAF2 YY1 associated factor 2
ZNF277 zinc finger protein 277
ZNF518A zinc finger protein 518A
ZNF576 zinc finger protein 576
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADAM9 ADAM metallopeptidase domain 9
ADM2 adrenomedullin 2
AHCTF1 AT hook containing transcription factor 1
AHSP alpha hemoglobin stabilizing protein
ANO10 anoctamin 10
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP13A2 ATPase type 13A2
AUH AU RNA binding protein/enoyl-CoA hydratase
C11ORF80 chromosome 11 open reading frame 80
C17ORF62 chromosome 17 open reading frame 62
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF31 chromosome 22 open reading frame 31
CA11 carbonic anhydrase XI
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC94 coiled-coil domain containing 94
CCNJL cyclin J-like
CD53 CD53 molecule
CDK5 cyclin-dependent kinase 5
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSF cathepsin F
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DDHD2 DDHD domain containing 2
DET1 de-etiolated homolog 1 (Arabidopsis)
DISC1 disrupted in schizophrenia 1
E4F1 E4F transcription factor 1
EFNA3 ephrin-A3
FBXL15 F-box and leucine-rich repeat protein 15
FGF16 fibroblast growth factor 16
FLJ11710 uncharacterized protein FLJ11710
FRAS1 Fraser extracellular matrix complex subunit 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GRPR gastrin-releasing peptide receptor
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HDAC7 histone deacetylase 7
HHLA1 HERV-H LTR-associating 1
HIRIP3 HIRA interacting protein 3
HIST1H3J histone cluster 1, H3j
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFLR1 IGF-like family receptor 1
IL15RA interleukin 15 receptor, alpha
INE1 inactivation escape 1 (non-protein coding)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCTD3 potassium channel tetramerization domain containing 3
KLHL28 kelch-like family member 28
LAS1L LAS1-like (S. cerevisiae)
LENEP lens epithelial protein
LIMS2 LIM and senescent cell antigen-like domains 2
LRRC37A3 leucine rich repeat containing 37, member A3
MITF microphthalmia-associated transcription factor
NKX2-5 NK2 homeobox 5
NPFFR1 neuropeptide FF receptor 1
NTNG1 netrin G1
NXPH3 neurexophilin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCEL1 occludin/ELL domain containing 1
PDZD7 PDZ domain containing 7
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD2 polycystic kidney disease 2 (autosomal dominant)
POMT2 protein-O-mannosyltransferase 2
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PTCD1 pentatricopeptide repeat domain 1
RAB3A RAB3A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBM14 RNA binding motif protein 14
REC8 REC8 meiotic recombination protein
RECQL4 RecQ protein-like 4
RND1 Rho family GTPase 1
RNF111 ring finger protein 111
RPAP2 RNA polymerase II associated protein 2
RPE ribulose-5-phosphate-3-epimerase
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SERINC1 serine incorporator 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SOD3 superoxide dismutase 3, extracellular
SRPK3 SRSF protein kinase 3
STEAP3 STEAP family member 3, metalloreductase
SULT4A1 sulfotransferase family 4A, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYF2 SYF2 pre-mRNA-splicing factor
TMEM183A transmembrane protein 183A
TNF tumor necrosis factor
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTF2 transcription termination factor, RNA polymerase II
ULBP2 UL16 binding protein 2
USP20 ubiquitin specific peptidase 20
VAX2 ventral anterior homeobox 2
VPREB3 pre-B lymphocyte 3
WNT10B wingless-type MMTV integration site family, member 10B
ZFP36 ZFP36 ring finger protein
ZNF646 zinc finger protein 646
ZNHIT2 zinc finger, HIT-type containing 2