celecoxib-252 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the celecoxib-252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACAN aggrecan
AGFG2 ArfGAP with FG repeats 2
AK1 adenylate kinase 1
ALPK1 alpha-kinase 1
AQP8 aquaporin 8
ARHGAP35 Rho GTPase activating protein 35
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSF arylsulfatase F
ASIC3 acid sensing (proton gated) ion channel 3
ATXN8OS ATXN8 opposite strand (non-protein coding)
AXIN1 axin 1
BHMT betaine--homocysteine S-methyltransferase
C17ORF59 chromosome 17 open reading frame 59
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHRM2 cholinergic receptor, muscarinic 2
CLEC4E C-type lectin domain family 4, member E
CST4 cystatin S
DOK3 docking protein 3
DUS2 dihydrouridine synthase 2
DYSF dysferlin
EMX1 empty spiracles homeobox 1
EPOR erythropoietin receptor
ESPN espin
FAM188A family with sequence similarity 188, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGR FGR proto-oncogene, Src family tyrosine kinase
FXR2 fragile X mental retardation, autosomal homolog 2
FXYD6 FXYD domain containing ion transport regulator 6
GAL3ST4 galactose-3-O-sulfotransferase 4
GLDC glycine dehydrogenase (decarboxylating)
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR135 G protein-coupled receptor 135
GRIP2 glutamate receptor interacting protein 2
HNF1A HNF1 homeobox A
HPX hemopexin
HRH1 histamine receptor H1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKZF2 IKAROS family zinc finger 2 (Helios)
IL5RA interleukin 5 receptor, alpha
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0141 KIAA0141
KLHL35 kelch-like family member 35
LIAS lipoic acid synthetase
LMTK2 lemur tyrosine kinase 2
LUZP1 leucine zipper protein 1
MAPK8 mitogen-activated protein kinase 8
MGC2889 uncharacterized protein MGC2889
MLXIPL MLX interacting protein-like
MN1 meningioma (disrupted in balanced translocation) 1
MT1G metallothionein 1G
MTMR2 myotubularin related protein 2
NCOR2 nuclear receptor corepressor 2
NNAT neuronatin
NOV nephroblastoma overexpressed
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PAX1 paired box 1
PCDHB8 protocadherin beta 8
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PLXNB3 plexin B3
PNOC prepronociceptin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PQLC3 PQ loop repeat containing 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTK6 protein tyrosine kinase 6
QTRT1 queuine tRNA-ribosyltransferase 1
RANBP10 RAN binding protein 10
RB1 retinoblastoma 1
RNASE3 ribonuclease, RNase A family, 3
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPL14 ribosomal protein L14
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SGSH N-sulfoglucosamine sulfohydrolase
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
STAB2 stabilin 2
TBCD tubulin folding cofactor D
TM4SF1 transmembrane 4 L six family member 1
TM4SF5 transmembrane 4 L six family member 5
TM7SF3 transmembrane 7 superfamily member 3
TMEM161A transmembrane protein 161A
TMEM70 transmembrane protein 70
TNS1 tensin 1
TOP3A topoisomerase (DNA) III alpha
TRAFD1 TRAF-type zinc finger domain containing 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN32 tetraspanin 32
USP20 ubiquitin specific peptidase 20
WDR1 WD repeat domain 1
WIPF1 WAS/WASL interacting protein family, member 1
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
ADAMTSL4 ADAMTS-like 4
ADGRE5 adhesion G protein-coupled receptor E5
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX15 arachidonate 15-lipoxygenase
AMELY amelogenin, Y-linked
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATXN2 ataxin 2
AZI2 5-azacytidine induced 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAV3 caveolin 3
CCDC132 coiled-coil domain containing 132
CCDC81 coiled-coil domain containing 81
CD180 CD180 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK3 cyclin-dependent kinase 3
CHGA chromogranin A
CLEC2B C-type lectin domain family 2, member B
CLEC7A C-type lectin domain family 7, member A
CPA3 carboxypeptidase A3 (mast cell)
CRNN cornulin
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DNASE1L2 deoxyribonuclease I-like 2
DRP2 dystrophin related protein 2
DUSP22 dual specificity phosphatase 22
DUX1 double homeobox 1
EGR2 early growth response 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPX eosinophil peroxidase
F3 coagulation factor III (thromboplastin, tissue factor)
FAM110B family with sequence similarity 110, member B
FAM110D family with sequence similarity 110, member D
FGF6 fibroblast growth factor 6
FKBP10 FK506 binding protein 10, 65 kDa
FTCD formimidoyltransferase cyclodeaminase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLMN glomulin, FKBP associated protein
GPR1 G protein-coupled receptor 1
GSTT1 glutathione S-transferase theta 1
GUCA1B guanylate cyclase activator 1B (retina)
HCRTR2 hypocretin (orexin) receptor 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
ISL1 ISL LIM homeobox 1
KIFAP3 kinesin-associated protein 3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLHDC8A kelch domain containing 8A
KLHL36 kelch-like family member 36
LENEP lens epithelial protein
LHX1 LIM homeobox 1
LOC100127972 uncharacterized LOC100127972
LOC441601 septin 7 pseudogene
LY6G6D lymphocyte antigen 6 complex, locus G6D
MAGOHB mago-nashi homolog B (Drosophila)
MOB3B MOB kinase activator 3B
MOGAT2 monoacylglycerol O-acyltransferase 2
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTERF4 mitochondrial transcription termination factor 4
MTRF1 mitochondrial translational release factor 1
MXRA5 matrix-remodelling associated 5
NPPB natriuretic peptide B
OLFML2B olfactomedin-like 2B
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAX4 paired box 4
PGBD5 piggyBac transposable element derived 5
PIEZO2 piezo-type mechanosensitive ion channel component 2
PKD2L1 polycystic kidney disease 2-like 1
POU5F1B POU class 5 homeobox 1B
PRDM14 PR domain containing 14
PRF1 perforin 1 (pore forming protein)
PRMT8 protein arginine methyltransferase 8
PRR4 proline rich 4 (lacrimal)
PTPRT protein tyrosine phosphatase, receptor type, T
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RNF141 ring finger protein 141
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A7 S100 calcium binding protein A7
SAMHD1 SAM domain and HD domain 1
SATB1 SATB homeobox 1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SND1-IT1 SND1 intronic transcript 1
TMEM176A transmembrane protein 176A
TMSB4Y thymosin beta 4, Y-linked
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
UGT8 UDP glycosyltransferase 8
VN1R1 vomeronasal 1 receptor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBTB44 zinc finger and BTB domain containing 44
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF23 zinc finger protein 23
ZNF516 zinc finger protein 516
ZNF623 zinc finger protein 623