celecoxib-377 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the celecoxib-377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
AKAP7 A kinase (PRKA) anchor protein 7
ALOX15B arachidonate 15-lipoxygenase, type B
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL4A ADP-ribosylation factor-like 4A
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB13 ankyrin repeat and SOCS box containing 13
AVIL advillin
BTN2A1 butyrophilin, subfamily 2, member A1
C4BPA complement component 4 binding protein, alpha
C6ORF106 chromosome 6 open reading frame 106
C7ORF26 chromosome 7 open reading frame 26
CA5BP1 carbonic anhydrase VB pseudogene 1
CACTIN cactin, spliceosome C complex subunit
CADM1 cell adhesion molecule 1
CAV3 caveolin 3
CBX6 chromobox homolog 6
CCL2 chemokine (C-C motif) ligand 2
CD82 CD82 molecule
CHERP calcium homeostasis endoplasmic reticulum protein
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CTNS cystinosin, lysosomal cystine transporter
CYLD cylindromatosis (turban tumor syndrome)
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
ELAC2 elaC ribonuclease Z 2
F12 coagulation factor XII (Hageman factor)
FKBP8 FK506 binding protein 8, 38kDa
FOSL1 FOS-like antigen 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH4 G patch domain containing 4
GRK6 G protein-coupled receptor kinase 6
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HEATR3 HEAT repeat containing 3
HEATR6 HEAT repeat containing 6
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IRGQ immunity-related GTPase family, Q
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0141 KIAA0141
KLHL3 kelch-like family member 3
LDOC1 leucine zipper, down-regulated in cancer 1
LOC729164 hCG1732469
LPPR2 lipid phosphate phosphatase-related protein type 2
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRPL41 mitochondrial ribosomal protein L41
MT1HL1 metallothionein 1H-like 1
NDRG3 NDRG family member 3
NFX1 nuclear transcription factor, X-box binding 1
NIPAL2 NIPA-like domain containing 2
NSFL1C NSFL1 (p97) cofactor (p47)
NXPH3 neurexophilin 3
OLIG2 oligodendrocyte lineage transcription factor 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PDZD7 PDZ domain containing 7
POLG polymerase (DNA directed), gamma
PPP4C protein phosphatase 4, catalytic subunit
PRB1 proline-rich protein BstNI subfamily 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PYGO1 pygopus family PHD finger 1
R3HCC1 R3H domain and coiled-coil containing 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RPL37A ribosomal protein L37a
RPL39L ribosomal protein L39-like
SELPLG selectin P ligand
SEPHS1 selenophosphate synthetase 1
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP2 SH3-domain binding protein 2
SKAP2 src kinase associated phosphoprotein 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG7 SMG7 nonsense mediated mRNA decay factor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNTG1 syntrophin, gamma 1
SPATA5L1 spermatogenesis associated 5-like 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX2 T-box 2
TEX261 testis expressed 261
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIPIN TIMELESS interacting protein
TMEM161A transmembrane protein 161A
TMEM80 transmembrane protein 80
TMEM97 transmembrane protein 97
TRD T cell receptor delta locus
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC37 tetratricopeptide repeat domain 37
TUBA4B tubulin, alpha 4b
USF2 upstream transcription factor 2, c-fos interacting
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
VPRBP Vpr (HIV-1) binding protein
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACP6 acid phosphatase 6, lysophosphatidic
ACVRL1 activin A receptor type II-like 1
ADAP2 ArfGAP with dual PH domains 2
ANKRD55 ankyrin repeat domain 55
AOAH acyloxyacyl hydrolase (neutrophil)
APOD apolipoprotein D
ARRB2 arrestin, beta 2
ASAP1-IT1 ASAP1 intronic transcript 1
BHMT betaine--homocysteine S-methyltransferase
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCDC71 coiled-coil domain containing 71
CCR4 chemokine (C-C motif) receptor 4
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CEP170B centrosomal protein 170B
CLCF1 cardiotrophin-like cytokine factor 1
CLEC1A C-type lectin domain family 1, member A
CNR2 cannabinoid receptor 2 (macrophage)
CRYAB crystallin, alpha B
CRYBB2P1 crystallin, beta B2 pseudogene 1
DCTN4 dynactin 4 (p62)
DUSP13 dual specificity phosphatase 13
ECM1 extracellular matrix protein 1
ERCC4 excision repair cross-complementation group 4
ETNK2 ethanolamine kinase 2
FAM189A2 family with sequence similarity 189, member A2
FAM64A family with sequence similarity 64, member A
FBXO46 F-box protein 46
FCHSD2 FCH and double SH3 domains 2
GIPC1 GIPC PDZ domain containing family, member 1
GML glycosylphosphatidylinositol anchored molecule like
GPA33 glycoprotein A33 (transmembrane)
GRHL2 grainyhead-like 2 (Drosophila)
GRPR gastrin-releasing peptide receptor
GSTA4 glutathione S-transferase alpha 4
HAND1 heart and neural crest derivatives expressed 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTRA1 HtrA serine peptidase 1
JOSD1 Josephin domain containing 1
JUP junction plakoglobin
KIAA0430 KIAA0430
KRCC1 lysine-rich coiled-coil 1
KRT37 keratin 37, type I
LEMD3 LEM domain containing 3
LHX3 LIM homeobox 3
LIMS2 LIM and senescent cell antigen-like domains 2
LMAN2L lectin, mannose-binding 2-like
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MCTP2 multiple C2 domains, transmembrane 2
MINPP1 multiple inositol-polyphosphate phosphatase 1
MKS1 Meckel syndrome, type 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
NEO1 neogenin 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PHF11 PHD finger protein 11
PIGR polymeric immunoglobulin receptor
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLCD1 phospholipase C, delta 1
PRDM5 PR domain containing 5
PRKCE protein kinase C, epsilon
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RABL3 RAB, member of RAS oncogene family-like 3
RAMP3 receptor (G protein-coupled) activity modifying protein 3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPA17 sperm autoantigenic protein 17
SPDL1 spindle apparatus coiled-coil protein 1
SPP2 secreted phosphoprotein 2, 24kDa
SPRR1B small proline-rich protein 1B
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STRA6 stimulated by retinoic acid 6
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAS2R1 taste receptor, type 2, member 1
TGFB3 transforming growth factor, beta 3
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRB thyroid hormone receptor, beta
TMEM159 transmembrane protein 159
TPST1 tyrosylprotein sulfotransferase 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBQLN4 ubiquilin 4
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
VIPR1 vasoactive intestinal peptide receptor 1
VWA9 von Willebrand factor A domain containing 9
ZBTB16 zinc finger and BTB domain containing 16
ZBTB48 zinc finger and BTB domain containing 48
ZNF219 zinc finger protein 219
ZNF770 zinc finger protein 770