celiac disease Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite. (Human Disease Ontology, DOID_10608)
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Genes

130 genes associated with the disease celiac disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADAD1 adenosine deaminase domain containing 1 (testis-specific)
AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
ARHGAP31 Rho GTPase activating protein 31
ATXN2 ataxin 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR9 chemokine (C-C motif) receptor 9
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD80 CD80 molecule
CIITA class II, major histocompatibility complex, transactivator
CLEC16A C-type lectin domain family 16, member A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DEFB103A defensin, beta 103A
DEFB104A defensin, beta 104A
DMPK dystrophia myotonica-protein kinase
ELMO1 engulfment and cell motility 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF1 fibroblast growth factor 1 (acidic)
FRMD4B FERM domain containing 4B
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-G major histocompatibility complex, class I, G
HP haptoglobin
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IK IK cytokine, down-regulator of HLA II
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12A interleukin 12A
IL12B interleukin 12B
IL17B interleukin 17B
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL3 interleukin 3
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL9 interleukin 9
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JAKMIP2 janus kinase and microtubule interacting protein 2
KIAA1109 KIAA1109
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LPP LIM domain containing preferred translocation partner in lipoma
LTA lymphotoxin alpha
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MBL2 mannose-binding lectin (protein C) 2, soluble
MICA MHC class I polypeptide-related sequence A
MMEL1 membrane metallo-endopeptidase-like 1
MMP3 matrix metallopeptidase 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYNN myoneurin
MYO9B myosin IXB
NFIA nuclear factor I/A
NOD2 nucleotide-binding oligomerization domain containing 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARK7 parkinson protein 7
PLEK pleckstrin
POGLUT1 protein O-glucosyltransferase 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRK protein tyrosine phosphatase, receptor type, K
PUS10 pseudouridylate synthase 10
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGS1 regulator of G-protein signaling 1
RUNX3 runt-related transcription factor 3
SCHIP1 schwannomin interacting protein 1
SH2B3 SH2B adaptor protein 3
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SOCS1 suppressor of cytokine signaling 1
SPINK1 serine peptidase inhibitor, Kazal type 1
STK32A serine/threonine kinase 32A
TAGAP T-cell activation RhoGTPase activating protein
TCERG1 transcription elongation regulator 1
TGFB1 transforming growth factor, beta 1
THEMIS thymocyte selection associated
THY1 Thy-1 cell surface antigen
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2L3 ubiquitin-conjugating enzyme E2L 3
WNT3 wingless-type MMTV integration site family, member 3
YDJC YdjC homolog (bacterial)
YIPF5 Yip1 domain family, member 5
ZFP36L1 ZFP36 ring finger protein-like 1
ZMIZ1 zinc finger, MIZ-type containing 1