cell leading edge Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description The area of a motile cell closest to the direction of movement. (Gene Ontology, GO_0031252)
External Link http://amigo.geneontology.org/amigo/term/GO:0031252
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Genes

31 proteins localized to the cell leading edge cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ARF1 ADP-ribosylation factor 1
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
BCAS3 breast carcinoma amplified sequence 3
BSPRY B-box and SPRY domain containing
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CORO1B coronin, actin binding protein, 1B
CXCR4 chemokine (C-X-C motif) receptor 4
DCTN1 dynactin 1
DOCK8 dedicator of cytokinesis 8
DST dystonin
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
HDAC6 histone deacetylase 6
IQGAP1 IQ motif containing GTPase activating protein 1
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
JMY junction mediating and regulatory protein, p53 cofactor
KDF1 keratinocyte differentiation factor 1
MYH9 myosin, heavy chain 9, non-muscle
NDEL1 nudE neurodevelopment protein 1-like 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
SCRIB scribbled planar cell polarity protein
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
TUBG1 tubulin, gamma 1
VIM vimentin
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta