cell-substrate junction Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description A cell junction that forms a connection between a cell and the extracellular matrix. (Gene Ontology, GO_0030055)
External Link http://amigo.geneontology.org/amigo/term/GO:0030055
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Genes

396 proteins localized to the cell-substrate junction cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACTB actin, beta
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACTN2 actinin, alpha 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACTN4 actinin, alpha 4
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM9 ADAM metallopeptidase domain 9
ADD1 adducin 1 (alpha)
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
AHNAK AHNAK nucleoprotein
AIF1L allograft inflammatory factor 1-like
AKAP12 A kinase (PRKA) anchor protein 12
ALCAM activated leukocyte cell adhesion molecule
ALKBH6 alkB, alkylation repair homolog 6 (E. coli)
ALOX15B arachidonate 15-lipoxygenase, type B
ANXA1 annexin A1
ANXA5 annexin A5
ANXA6 annexin A6
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ARHGAP22 Rho GTPase activating protein 22
ARHGAP24 Rho GTPase activating protein 24
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL14EP ADP-ribosylation factor-like 14 effector protein
ARL2 ADP-ribosylation factor-like 2
ARMC5 armadillo repeat containing 5
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARPC5L actin related protein 2/3 complex, subunit 5-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
AVIL advillin
B2M beta-2-microglobulin
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BSG basigin (Ok blood group)
C19ORF35 chromosome 19 open reading frame 35
CALR calreticulin
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CAPN5 calpain 5
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASS4 Cas scaffolding protein family member 4
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CD151 CD151 molecule (Raph blood group)
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CD81 CD81 molecule
CD9 CD9 molecule
CD99 CD99 molecule
CD99L2 CD99 molecule-like 2
CDC42 cell division cycle 42
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH13 cadherin 13
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEL carboxyl ester lipase
CFL1 cofilin 1 (non-muscle)
CHP1 calcineurin-like EF-hand protein 1
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLTC clathrin, heavy chain (Hc)
CNN1 calponin 1, basic, smooth muscle
CNN2 calponin 2
CNN3 calponin 3, acidic
COL17A1 collagen, type XVII, alpha 1
CORO1B coronin, actin binding protein, 1B
CORO1C coronin, actin binding protein, 1C
CORO2B coronin, actin binding protein, 2B
CPNE3 copine III
CSPG4 chondroitin sulfate proteoglycan 4
CSRP1 cysteine and glycine-rich protein 1
CSRP2 cysteine and glycine-rich protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCR4 chemokine (C-X-C motif) receptor 4
CYFIP1 cytoplasmic FMR1 interacting protein 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCAF6 DDB1 and CUL4 associated factor 6
DDR2 discoidin domain receptor tyrosine kinase 2
DMD dystrophin
DNM2 dynamin 2
DOCK7 dedicator of cytokinesis 7
DPP4 dipeptidyl-peptidase 4
DST dystonin
DYNLL1 dynein, light chain, LC8-type 1
EFNB2 ephrin-B2
EFS embryonal Fyn-associated substrate
EGFR epidermal growth factor receptor
EHD3 EH-domain containing 3
ENAH enabled homolog (Drosophila)
ENG endoglin
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
ERBIN erbb2 interacting protein
EVL Enah/Vasp-like
EZR ezrin
FAM107A family with sequence similarity 107, member A
FAT1 FAT atypical cadherin 1
FBLIM1 filamin binding LIM protein 1
FBLN7 fibulin 7
FERMT1 fermitin family member 1
FERMT2 fermitin family member 2
FERMT3 fermitin family member 3
FES FES proto-oncogene, tyrosine kinase
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FHL2 four and a half LIM domains 2
FHL3 four and a half LIM domains 3
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
FLOT1 flotillin 1
FLOT2 flotillin 2
FLRT1 fibronectin leucine rich transmembrane protein 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
FOCAD focadhesin
FZD1 frizzled class receptor 1
FZD2 frizzled class receptor 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GDI2 GDP dissociation inhibitor 2
GFRAL GDNF family receptor alpha like
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA1 gap junction protein, alpha 1, 43kDa
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GRB7 growth factor receptor-bound protein 7
GSN gelsolin
HACD3 3-hydroxyacyl-CoA dehydratase 3
HCK HCK proto-oncogene, Src family tyrosine kinase
HMCN1 hemicentin 1
HMGA1 high mobility group AT-hook 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPG2 heparan sulfate proteoglycan 2
HYOU1 hypoxia up-regulated 1
ICAM1 intercellular adhesion molecule 1
IGF2R insulin-like growth factor 2 receptor
IL16 interleukin 16
IL33R interleukin 33 receptor
ILK integrin-linked kinase
IQGAP1 IQ motif containing GTPase activating protein 1
IRF2 interferon regulatory factor 2
ITGA1 integrin, alpha 1
ITGA11 integrin, alpha 11
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGA8 integrin, alpha 8
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
ITGB7 integrin, beta 7
ITGB8 integrin, beta 8
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUP junction plakoglobin
KIF23 kinesin family member 23
KLF11 Kruppel-like factor 11
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LASP1 LIM and SH3 protein 1
LAYN layilin
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIMA1 LIM domain and actin binding 1
LIMD1 LIM domains containing 1
LIMS1 LIM and senescent cell antigen-like domains 1
LIMS2 LIM and senescent cell antigen-like domains 2
LMLN leishmanolysin-like (metallopeptidase M8 family)
LMO7 LIM domain 7
LPP LIM domain containing preferred translocation partner in lipoma
LPXN leupaxin
LRP1 low density lipoprotein receptor-related protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MCAM melanoma cell adhesion molecule
MDC1 mediator of DNA-damage checkpoint 1
MISP mitotic spindle positioning
MME membrane metallo-endopeptidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPRIP myosin phosphatase Rho interacting protein
MPZL1 myelin protein zero-like 1
MRC2 mannose receptor, C type 2
MSN moesin
MYH9 myosin, heavy chain 9, non-muscle
NCKAP1 NCK-associated protein 1
NCSTN nicastrin
NECTIN2 nectin cell adhesion molecule 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NELL1 NEL-like 1 (chicken)
NEXN nexilin (F actin binding protein)
NFASC neurofascin
NME2 NME/NM23 nucleoside diphosphate kinase 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAP nebulin-related anchoring protein
NUMB numb homolog (Drosophila)
P4HB prolyl 4-hydroxylase, beta polypeptide
PABPC1 poly(A) binding protein, cytoplasmic 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALLD palladin, cytoskeletal associated protein
PARVA parvin, alpha
PARVB parvin, beta
PARVG parvin, gamma
PCBP2 poly(rC) binding protein 2
PDCD6IP programmed cell death 6 interacting protein
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PDLIM1 PDZ and LIM domain 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PEAK1 pseudopodium-enriched atypical kinase 1
PFN1 profilin 1
PGM5 phosphoglucomutase 5
PHLDB2 pleckstrin homology-like domain, family B, member 2
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLEC plectin
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRAG1 PEAK1 related, kinase-activating pseudokinase 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PROCR protein C receptor, endothelial
PRSS8 protease, serine, 8
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK7 protein tyrosine kinase 7 (inactive)
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRC protein tyrosine phosphatase, receptor type, C
PVR poliovirus receptor
PXN paxillin
RAB10 RAB10, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RDX radixin
REXO2 RNA exonuclease 2
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOG ras homolog family member G
RND3 Rho family GTPase 3
RPL10A ribosomal protein L10a
RPL12 ribosomal protein L12
RPL13A ribosomal protein L13a
RPL17 ribosomal protein L17
RPL18 ribosomal protein L18
RPL19 ribosomal protein L19
RPL22 ribosomal protein L22
RPL27 ribosomal protein L27
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPL4 ribosomal protein L4
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPL9 ribosomal protein L9
RPLP0 ribosomal protein, large, P0
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15 ribosomal protein S15
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS5 ribosomal protein S5
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSU1 Ras suppressor protein 1
S100A7 S100 calcium binding protein A7
SCARB2 scavenger receptor class B, member 2
SCARF2 scavenger receptor class F, member 2
SENP1 SUMO1/sentrin specific peptidase 1
SHROOM4 shroom family member 4
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMPX small muscle protein, X-linked
SNAP23 synaptosomal-associated protein, 23kDa
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SORBS1 sorbin and SH3 domain containing 1
SORBS3 sorbin and SH3 domain containing 3
SPRY4 sprouty homolog 4 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRCIN1 SRC kinase signaling inhibitor 1
SRP68 signal recognition particle 68kDa
STX16 syntaxin 16
SVIL supervillin
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNPO2 synaptopodin 2
TES testin LIM domain protein
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGM2 transglutaminase 2
THSD1 thrombospondin, type I, domain containing 1
THY1 Thy-1 cell surface antigen
TLE2 transducin-like enhancer of split 2
TLN1 talin 1
TLN2 talin 2
TM4SF20 transmembrane 4 L six family member 20
TMEM98 transmembrane protein 98
TNC tenascin C
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNS1 tensin 1
TNS2 tensin 2
TNS3 tensin 3
TNS4 tensin 4
TPM4 tropomyosin 4
TRIOBP TRIO and F-actin binding protein
TRIP6 thyroid hormone receptor interactor 6
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSPAN4 tetraspanin 4
TSPAN9 tetraspanin 9
TWF1 twinfilin actin binding protein 1
UBOX5 U-box domain containing 5
USP33 ubiquitin specific peptidase 33
VASP vasodilator-stimulated phosphoprotein
VCL vinculin
VIM vimentin
XIRP1 xin actin binding repeat containing 1
XIRP2 xin actin binding repeat containing 2
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZYX zyxin