cell-transformation-neoplastic Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

197 proteins co-occuring with the biological term cell-transformation-neoplastic in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACLY ATP citrate lyase
AICDA activation-induced cytidine deaminase
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ALK anaplastic lymphoma receptor tyrosine kinase
AQP5 aquaporin 5
AR androgen receptor
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BLK BLK proto-oncogene, Src family tyrosine kinase
BMX BMX non-receptor tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC50 coiled-coil domain containing 50
CCND1 cyclin D1
CCNE1 cyclin E1
CDC25C cell division cycle 25C
CDCA5 cell division cycle associated 5
CDCA7 cell division cycle associated 7
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
COPS6 COP9 signalosome subunit 6
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CUEDC2 CUE domain containing 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DBNL drebrin-like
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DYNLL1 dynein, light chain, LC8-type 1
E2F1 E2F transcription factor 1
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF6 eukaryotic translation initiation factor 6
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELK1 ELK1, member of ETS oncogene family
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FBXO4 F-box protein 4
FHIT fragile histidine triad
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA2 forkhead box A2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FYN FYN proto-oncogene, Src family tyrosine kinase
GJA1 gap junction protein, alpha 1, 43kDa
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
H3F3B H3 histone, family 3B (H3.3B)
HCK HCK proto-oncogene, Src family tyrosine kinase
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HIST1H3B histone cluster 1, H3b
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRF3 interferon regulatory factor 3
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT8 keratin 8, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAK male germ cell-associated kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MKL1 megakaryoblastic leukemia (translocation) 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MPL MPL proto-oncogene, thrombopoietin receptor
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
NCOR1 nuclear receptor corepressor 1
NEK6 NIMA-related kinase 6
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PHGDH phosphoglycerate dehydrogenase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD2 phospholipase D2
PLK4 polo-like kinase 4
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PXN paxillin
RACGAP1 Rac GTPase activating protein 1
RAD17 RAD17 homolog (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RICTOR RPTOR independent companion of MTOR, complex 2
RPA2 replication protein A2, 32kDa
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RXRA retinoid X receptor, alpha
S100A11 S100 calcium binding protein A11
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SH3GL1 SH3-domain GRB2-like 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLK STE20-like kinase
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD5 SMAD family member 5
SMAD9 SMAD family member 9
SPHK1 sphingosine kinase 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSB Sjogren syndrome antigen B (autoantigen La)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STYK1 serine/threonine/tyrosine kinase 1
TBX2 T-box 2
TOB1 transducer of ERBB2, 1
TP53 tumor protein p53
TP73 tumor protein p73
TSC2 tuberous sclerosis 2
USP28 ubiquitin specific peptidase 28
VAV1 vav 1 guanine nucleotide exchange factor
WDR77 WD repeat domain 77
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1