cellular response to hypoxia Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. (Gene Ontology, GO_0071456)
External Link http://amigo.geneontology.org/amigo/term/GO_0071456
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Genes

73 genes participating in the cellular response to hypoxia biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADAM8 ADAM metallopeptidase domain 8
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AK4 adenylate kinase 4
ANGPT4 angiopoietin 4
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
BAD BCL2-associated agonist of cell death
BMP7 bone morphogenetic protein 7
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPEB2 cytoplasmic polyadenylation element binding protein 2
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EPAS1 endothelial PAS domain protein 1
FABP1 fatty acid binding protein 1, liver
FAM162A family with sequence similarity 162, member A
FMN2 formin 2
GATA6 GATA binding protein 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HILPDA hypoxia inducible lipid droplet-associated
HIPK2 homeodomain interacting protein kinase 2
HMOX1 heme oxygenase 1
HP1BP3 heterochromatin protein 1, binding protein 3
HYOU1 hypoxia up-regulated 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
LMNA lamin A/C
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MGARP mitochondria-localized glutamic acid-rich protein
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MT3 metallothionein 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDNF neuron-derived neurotrophic factor
NDRG1 N-myc downstream regulated 1
NKX3-1 NK3 homeobox 1
NOP53 NOP53 ribosome biogenesis factor
NOTCH1 notch 1
NPEPPS aminopeptidase puromycin sensitive
OPRD1 opioid receptor, delta 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PGK1 phosphoglycerate kinase 1
PINK1 PTEN induced putative kinase 1
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARG peroxisome proliferator-activated receptor gamma
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
RORA RAR-related orphan receptor A
RPTOR regulatory associated protein of MTOR, complex 1
SCN2A sodium channel, voltage gated, type II alpha subunit
SFRP1 secreted frizzled-related protein 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
STOX1 storkhead box 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBL2 transducin (beta)-like 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TP53 tumor protein p53
TWIST1 twist family bHLH transcription factor 1
UBQLN1 ubiquilin 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZFP36L1 ZFP36 ring finger protein-like 1