cellular response to insulin stimulus Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. (Gene Ontology, GO_0032869)
External Link http://amigo.geneontology.org/amigo/term/GO:0032869
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Genes

109 genes participating in the cellular response to insulin stimulus biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
BAIAP2 BAI1-associated protein 2
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BGLAP bone gamma-carboxyglutamate (gla) protein
C2CD5 C2 calcium-dependent domain containing 5
CAPN10 calpain 10
CAV2 caveolin 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPEB2 cytoplasmic polyadenylation element binding protein 2
DENND4C DENN/MADD domain containing 4C
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPRS1 glutamyl-prolyl-tRNA synthetase 1
FER fer (fps/fes related) tyrosine kinase
FOXC2 forkhead box C2
FOXO1 forkhead box O1
FOXO4 forkhead box O4
GOLT1A golgi transport 1A
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
IDE insulin-degrading enzyme
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
INHBB inhibin, beta B
INPP5K inositol polyphosphate-5-phosphatase K
INS insulin
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
INSR insulin receptor
INSRR insulin receptor-related receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
KAT2B K(lysine) acetyltransferase 2B
LPIN1 lipin 1
LPIN2 lipin 2
LPIN3 lipin 3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPKAP1 mitogen-activated protein kinase associated protein 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO5A myosin VA (heavy chain 12, myoxin)
NAMPT nicotinamide phosphoribosyltransferase
OTOP1 otopetrin 1
PARP1 poly (ADP-ribose) polymerase 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPK1 3-phosphoinositide dependent protein kinase 1
PHIP pleckstrin homology domain interacting protein
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PKLR pyruvate kinase, liver and RBC
PKM pyruvate kinase, muscle
PLA2G1B phospholipase A2, group IB (pancreas)
PPARG peroxisome proliferator-activated receptor gamma
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB10 RAB10, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHOQ ras homolog family member Q
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SELENOS selenoprotein S
SH2B2 SH2B adaptor protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SOCS4 suppressor of cytokine signaling 4
SOGA1 suppressor of glucose, autophagy associated 1
SORBS1 sorbin and SH3 domain containing 1
STXBP4 syntaxin binding protein 4
SYAP1 synapse associated protein 1
TBC1D4 TBC1 domain family, member 4
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1
TRIB3 tribbles pseudokinase 3
USF1 upstream transcription factor 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XBP1 X-box binding protein 1
ZDHHC7 zinc finger, DHHC-type containing 7
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF106 zinc finger protein 106