cellular response to ionizing radiation Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. (Gene Ontology, GO_0071479)
External Link http://amigo.geneontology.org/amigo/term/GO_0071479
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Genes

53 genes participating in the cellular response to ionizing radiation biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BABAM2 BRISC and BRCA1 A complex member 2
BARD1 BRCA1 associated RING domain 1
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLOCK clock circadian regulator
CNOT12 CCR4-NOT transcription complex subunit 12
CRYAB crystallin, alpha B
DEPDC1B DEP domain containing 1B
ECT2 epithelial cell transforming 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
ERCC4 excision repair cross-complementation group 4
FIGNL1 fidgetin-like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
HSF1 heat shock transcription factor 1
HUS1 HUS1 checkpoint homolog (S. pombe)
IFI16 interferon, gamma-inducible protein 16
INO80 INO80 complex subunit
INTS7 integrator complex subunit 7
KDM1A lysine (K)-specific demethylase 1A
KDM4D lysine (K)-specific demethylase 4D
LIG4 ligase IV, DNA, ATP-dependent
MAP3K20 mitogen-activated protein kinase kinase kinase 20
MAPK14 mitogen-activated protein kinase 14
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NIPBL Nipped-B homolog (Drosophila)
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
PRAP1 proline-rich acidic protein 1
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD9A RAD9 homolog A (S. pombe)
RAD9B RAD9 homolog B (S. pombe)
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RHOB ras homolog family member B
RPL26 ribosomal protein L26
SIRT1 sirtuin 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPIDR scaffolding protein involved in DNA repair
SWI5 SWI5 recombination repair homolog (yeast)
TANK TRAF family member-associated NFKB activator
TLK2 tousled-like kinase 2
TMEM109 transmembrane protein 109
TP53 tumor protein p53
TSPYL5 TSPY-like 5
WRN Werner syndrome, RecQ helicase-like
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1