cellular response to metal ion Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. (Gene Ontology, GO_0071248)
External Link http://amigo.geneontology.org/amigo/term/GO:0071248
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Genes

113 genes participating in the cellular response to metal ion biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACER1 alkaline ceramidase 1
ADCY1 adenylate cyclase 1 (brain)
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
ADGRV1 adhesion G protein-coupled receptor V1
AKR1C3 aldo-keto reductase family 1, member C3
ALOX15 arachidonate 15-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AQP2 aquaporin 2 (collecting duct)
ASPH aspartate beta-hydroxylase
ATP13A2 ATPase type 13A2
B2M beta-2-microglobulin
BMP6 bone morphogenetic protein 6
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPN3 calpain 3, (p94)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHP2 calcineurin-like EF-hand protein 2
CLIC4 chloride intracellular channel 4
CPNE1 copine I
CPNE2 copine II
CPNE3 copine III
CPNE4 copine IV
CPNE5 copine V
CPNE6 copine VI (neuronal)
CPNE7 copine VII
CPNE8 copine VIII
CPNE9 copine family member IX
CRHBP corticotropin releasing hormone binding protein
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DAXX death-domain associated protein
DPEP1 dipeptidase 1 (renal)
ECT2 epithelial cell transforming 2
FBP1 fructose-1,6-bisphosphatase 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLRA1 glycine receptor, alpha 1
GLRA2 glycine receptor, alpha 2
GUCA1ANB-GUCA1A GUCA1ANB-GUCA1A readthrough
HFE hemochromatosis
HPCA hippocalcin
HSF1 heat shock transcription factor 1
HVCN1 hydrogen voltage gated channel 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITPKA inositol-trisphosphate 3-kinase A
ITPKB inositol-trisphosphate 3-kinase B
ITPKC inositol-trisphosphate 3-kinase C
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
LCE1D late cornified envelope 1D
LGMN legumain
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRK2 leucine-rich repeat kinase 2
MCOLN1 mucolipin 1
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MICU1 mitochondrial calcium uptake 1
MICU2 mitochondrial calcium uptake 2
MICU3 mitochondrial calcium uptake family, member 3
MINDY4 MINDY lysine 48 deubiquitinase 4
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MT1A metallothionein 1A
MT1B metallothionein 1B
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MT3 metallothionein 3
MT4 metallothionein 4
NEK7 NIMA-related kinase 7
NEUROD2 neuronal differentiation 2
NLGN1 neuroligin 1
NRXN1 neurexin 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PEDS1 plasmanylethanolamine desaturase 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPIF peptidylprolyl isomerase F
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKD2 protein kinase D2
PRKN parkin RBR E3 ubiquitin protein ligase
PRNP prion protein
RASA4 RAS p21 protein activator 4
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A39 solute carrier family 25, member 39
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLFN14 schlafen family member 14
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SUMO1 small ubiquitin-like modifier 1
SYT1 synaptotagmin I
TF transferrin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFR2 transferrin receptor 2
TIGAR TP53 induced glycolysis regulatory phosphatase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
WNT5A wingless-type MMTV integration site family, member 5A
ZNF658 zinc finger protein 658