cellular senescence Gene Set
Genes
28 genes participating in the cellular senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
| Symbol |
Name |
|
ARNTL
|
aryl hydrocarbon receptor nuclear translocator-like
|
|
C2ORF40
|
chromosome 2 open reading frame 40
|
|
CALR
|
calreticulin
|
|
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
|
HMGA1
|
high mobility group AT-hook 1
|
|
HMGA2
|
high mobility group AT-hook 2
|
|
HRAS
|
Harvey rat sarcoma viral oncogene homolog
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
|
MAP2K1
|
mitogen-activated protein kinase kinase 1
|
|
MAPK14
|
mitogen-activated protein kinase 14
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
|
NSMCE2
|
non-SMC element 2, MMS21 homolog (S. cerevisiae)
|
|
OPA1
|
optic atrophy 1 (autosomal dominant)
|
|
PLA2R1
|
phospholipase A2 receptor 1, 180kDa
|
|
PML
|
promyelocytic leukemia
|
|
PRKCD
|
protein kinase C, delta
|
|
SIRT1
|
sirtuin 1
|
|
SMC5
|
structural maintenance of chromosomes 5
|
|
SMC6
|
structural maintenance of chromosomes 6
|
|
SRF
|
serum response factor (c-fos serum response element-binding transcription factor)
|
|
TBX2
|
T-box 2
|
|
TBX3
|
T-box 3
|
|
TERF2
|
telomeric repeat binding factor 2
|
|
TP53
|
tumor protein p53
|
|
ULK3
|
unc-51 like kinase 3
|
|
WNT16
|
wingless-type MMTV integration site family, member 16
|