cenpa Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description centromere protein A|Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1058)
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Genes

20 genes co-occuring with the biological term cenpa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AURKA aurora kinase A
CENPA centromere protein A
CENPB centromere protein B, 80kDa
CENPC centromere protein C
CENPH centromere protein H
CENPI centromere protein I
CENPM centromere protein M
CENPN centromere protein N
CENPT centromere protein T
CENPW centromere protein W
CHD1 chromodomain helicase DNA binding protein 1
HIST1H3A histone cluster 1, H3a
HIST4H4 histone cluster 4, H4
HJURP Holliday junction recognition protein
PLK1 polo-like kinase 1
RB1 retinoblastoma 1
SSRP1 structure specific recognition protein 1
TP53 tumor protein p53
UNG uracil-DNA glycosylase
WDHD1 WD repeat and HMG-box DNA binding protein 1