centrosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. (Gene Ontology, GO_0005813)
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Genes

604 proteins co-occuring with the centrosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CNTLN centlein, centrosomal protein 2.68238
PCNT pericentrin 2.56008
PLK1 polo-like kinase 1 2.3392
NEK2 NIMA-related kinase 2 2.06122
PLK4 polo-like kinase 4 2.05685
NIN ninein (GSK3B interacting protein) 1.83203
AURKA aurora kinase A 1.72369
CENPJ centromere protein J 1.70199
CETN2 centrin, EF-hand protein, 2 1.68604
NUMA1 nuclear mitotic apparatus protein 1 1.66115
CEP152 centrosomal protein 152kDa 1.64972
CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.63837
CDK1 cyclin-dependent kinase 1 1.63598
CEP135 centrosomal protein 135kDa 1.61412
CDK2 cyclin-dependent kinase 2 1.56389
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 1.5548
BRCA1 breast cancer 1, early onset 1.55424
TPX2 TPX2, microtubule-associated 1.51694
CEP192 centrosomal protein 192kDa 1.50961
TP53 tumor protein p53 1.50001
DCTN1 dynactin 1 1.49944
TACC3 transforming, acidic coiled-coil containing protein 3 1.48305
STIL SCL/TAL1 interrupting locus 1.47174
AURKB aurora kinase B 1.47061
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 1.46043
CNTROB centrobin, centrosomal BRCA2 interacting protein 1.45703
MCPH1 microcephalin 1 1.41082
KIF11 kinesin family member 11 1.4097
PLK2 polo-like kinase 2 1.4041
CEP164 centrosomal protein 164kDa 1.37464
TUBA1A tubulin, alpha 1a 1.34883
NINL ninein-like 1.34447
CEP290 centrosomal protein 290kDa 1.33033
PCM1 pericentriolar material 1 1.32059
OFD1 oral-facial-digital syndrome 1 1.30819
CKAP5 cytoskeleton associated protein 5 1.29692
ODF2 outer dense fiber of sperm tails 2 1.29371
CEP63 centrosomal protein 63kDa 1.2921
CDC25B cell division cycle 25B 1.28836
CEP55 centrosomal protein 55kDa 1.27611
CCNB1 cyclin B1 1.22257
CETN1 centrin, EF-hand protein, 1 1.16184
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.1603
WDR62 WD repeat domain 62 1.15979
BBS4 Bardet-Biedl syndrome 4 1.12194
LATS2 large tumor suppressor kinase 2 1.11684
PLK3 polo-like kinase 3 1.1148
CETN3 centrin, EF-hand protein, 3 1.11276
DISC1 disrupted in schizophrenia 1 1.11123
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.10919
CHEK1 checkpoint kinase 1 1.10715
CEP250 centrosomal protein 250kDa 1.10511
CEP70 centrosomal protein 70kDa 1.10358
CSPP1 centrosome and spindle pole associated protein 1 1.08831
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.07917
CEP170 centrosomal protein 170kDa 1.06044
CEP120 centrosomal protein 120kDa 1.05741
AKAP9 A kinase (PRKA) anchor protein 9 1.05136
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.05085
CEP97 centrosomal protein 97kDa 1.04934
CDC20 cell division cycle 20 1.03129
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 1.02181
CCP110 centriolar coiled coil protein 110kDa 1.01833
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 1.01635
TUBE1 tubulin, epsilon 1 1.01436
MPEG1 macrophage expressed 1 1.01139
NDEL1 nudE neurodevelopment protein 1-like 1 1.00448
NEK6 NIMA-related kinase 6 1.0035
NPHP4 nephronophthisis 4 1.00153
TACC1 transforming, acidic coiled-coil containing protein 1 0.997104
NEK1 NIMA-related kinase 1 0.995632
ALMS1 Alstrom syndrome protein 1 0.995632
SDCCAG8 serologically defined colon cancer antigen 8 0.994652
MAP4 microtubule-associated protein 4 0.991714
TACC2 transforming, acidic coiled-coil containing protein 2 0.981959
NEK7 NIMA-related kinase 7 0.977589
AURKC aurora kinase C 0.970814
TUBGCP2 tubulin, gamma complex associated protein 2 0.951619
TUBD1 tubulin, delta 1 0.949713
CEP131 centrosomal protein 131kDa 0.940215
ZNF365 zinc finger protein 365 0.939742
AJUBA ajuba LIM protein 0.938322
NPHP1 nephronophthisis 1 (juvenile) 0.934544
CEP57 centrosomal protein 57kDa 0.933129
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.932187
CDC25C cell division cycle 25C 0.914376
ATM ATM serine/threonine kinase 0.910647
C2CD3 C2 calcium-dependent domain containing 3 0.900426
DCTN2 dynactin 2 (p50) 0.899036
NEK9 NIMA-related kinase 9 0.881016
KIZ kizuna centrosomal protein 0.880555
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.87733
INCENP inner centromere protein antigens 135/155kDa 0.874567
BRCA2 breast cancer 2, early onset 0.874107
SUN1 Sad1 and UNC84 domain containing 1 0.869966
MAP2 microtubule-associated protein 2 0.867206
POC1B POC1 centriolar protein B 0.852961
SCLT1 sodium channel and clathrin linker 1 0.846991
TRIP11 thyroid hormone receptor interactor 11 0.846532
HAUS6 HAUS augmin-like complex, subunit 6 0.844237
TTBK2 tau tubulin kinase 2 0.841941
POC1A POC1 centriolar protein A 0.83781
TBCCD1 TBCC domain containing 1 0.835056
MAPT microtubule-associated protein tau 0.82863
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.826794
POC5 POC5 centriolar protein 0.821288
IFT88 intraflagellar transport 88 0.819911
NEK8 NIMA-related kinase 8 0.81624
MKS1 Meckel syndrome, type 1 0.815322
HOOK2 hook microtubule-tethering protein 2 0.810735
CDK19 cyclin-dependent kinase 19 0.807982
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.80523
SASS6 spindle assembly 6 homolog (C. elegans) 0.804313
CSNK1D casein kinase 1, delta 0.802479
NEURL4 neuralized E3 ubiquitin protein ligase 4 0.796979
FOXJ1 forkhead box J1 0.795604
KIF2C kinesin family member 2C 0.789649
BARD1 BRCA1 associated RING domain 1 0.774101
TUBG1 tubulin, gamma 1 0.772732
BIRC5 baculoviral IAP repeat containing 5 0.766804
FGFR1OP FGFR1 oncogene partner 0.764982
CEP89 centrosomal protein 89kDa 0.763617
MARK4 MAP/microtubule affinity-regulating kinase 4 0.758161
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.758161
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.749546
SGOL1 shugoshin-like 1 (S. pombe) 0.749546
IFT20 intraflagellar transport 20 0.743671
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.74322
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.72258
H3F3A H3 histone, family 3A 0.71857
H3F3B H3 histone, family 3B (H3.3B) 0.71857
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 0.71768
STK38 serine/threonine kinase 38 0.715902
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 0.713238
AHI1 Abelson helper integration site 1 0.711465
NUF2 NUF2, NDC80 kinetochore complex component 0.70439
PTTG1 pituitary tumor-transforming 1 0.703507
CDC25A cell division cycle 25A 0.703507
PARD6A par-6 family cell polarity regulator alpha 0.701744
DNAH5 dynein, axonemal, heavy chain 5 0.699103
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.696465
DNAH12 dynein, axonemal, heavy chain 12 0.693393
DNAH14 dynein, axonemal, heavy chain 14 0.693393
RAB8A RAB8A, member RAS oncogene family 0.693393
PPP4C protein phosphatase 4, catalytic subunit 0.690326
TUBGCP4 tubulin, gamma complex associated protein 4 0.689451
CEP76 centrosomal protein 76kDa 0.688576
KLHDC8B kelch domain containing 8B 0.687264
AUNIP aurora kinase A and ninein interacting protein 0.687264
KIF23 kinesin family member 23 0.682899
CCDC8 coiled-coil domain containing 8 0.682463
SPAST spastin 0.675934
CEP83 centrosomal protein 83kDa 0.672894
NUBP1 nucleotide binding protein 1 0.668992
TMEM67 transmembrane protein 67 0.668559
CEP295 centrosomal protein 295kDa 0.668126
CENPE centromere protein E, 312kDa 0.666394
CDC42 cell division cycle 42 0.658188
CCNF cyclin F 0.654741
KATNB1 katanin p80 (WD repeat containing) subunit B 1 0.650869
XPO1 exportin 1 0.65001
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.64915
NUBP2 nucleotide binding protein 2 0.648291
KIF24 kinesin family member 24 0.642715
DNAH9 dynein, axonemal, heavy chain 9 0.633732
MOB1A MOB kinase activator 1A 0.632878
RAD51C RAD51 paralog C 0.632024
BICD2 bicaudal D homolog 2 (Drosophila) 0.631598
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.631171
SPATC1 spermatogenesis and centriole associated 1 0.630745
FAM161A family with sequence similarity 161, member A 0.630745
CLIP1 CAP-GLY domain containing linker protein 1 0.630745
CCDC78 coiled-coil domain containing 78 0.628187
RAD51 RAD51 recombinase 0.623079
KIAA0586 KIAA0586 0.623079
NDE1 nudE neurodevelopment protein 1 0.622229
CDC14A cell division cycle 14A 0.621804
CEP72 centrosomal protein 72kDa 0.616709
BBS2 Bardet-Biedl syndrome 2 0.614589
YPEL5 yippee-like 5 (Drosophila) 0.612048
E2F3 E2F transcription factor 3 0.609086
FBXO5 F-box protein 5 0.608663
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.607818
GADD45A growth arrest and DNA-damage-inducible, alpha 0.606973
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.60444
CDK11A cyclin-dependent kinase 11A 0.604017
CUL1 cullin 1 0.597276
H2AFX H2A histone family, member X 0.591392
RTTN rotatin 0.590973
SCYL1 SCY1-like 1 (S. cerevisiae) 0.590553
PARK2 parkin RBR E3 ubiquitin protein ligase 0.585523
KIF2A kinesin heavy chain member 2A 0.583431
USP33 ubiquitin specific peptidase 33 0.583012
CDK5 cyclin-dependent kinase 5 0.573828
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.570496
NUMB numb homolog (Drosophila) 0.569248
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.562602
MAP9 microtubule-associated protein 9 0.562187
DIDO1 death inducer-obliterator 1 0.562187
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.562187
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.562187
ARL13B ADP-ribosylation factor-like 13B 0.561772
SKP1 S-phase kinase-associated protein 1 0.555145
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.554318
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.548947
MOB1B MOB kinase activator 1B 0.53413
STK3 serine/threonine kinase 3 0.533309
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 0.532898
HDAC6 histone deacetylase 6 0.532078
ZNF385A zinc finger protein 385A 0.530438
CDKN2A cyclin-dependent kinase inhibitor 2A 0.530438
KLHL18 kelch-like family member 18 0.530438
AKAP1 A kinase (PRKA) anchor protein 1 0.530028
HAUS8 HAUS augmin-like complex, subunit 8 0.526341
RPGR retinitis pigmentosa GTPase regulator 0.525522
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.525113
XPC xeroderma pigmentosum, complementation group C 0.52225
RGS14 regulator of G-protein signaling 14 0.520206
TSSK2 testis-specific serine kinase 2 0.518981
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.512455
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.512047
CT55 cancer/testis antigen 55 0.511233
GAK cyclin G associated kinase 0.510826
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.510011
TUBGCP3 tubulin, gamma complex associated protein 3 0.510011
ARL3 ADP-ribosylation factor-like 3 0.50879
HSPA4 heat shock 70kDa protein 4 0.506757
SPAG5 sperm associated antigen 5 0.50635
FAM161B family with sequence similarity 161, member B 0.505537
TUBG2 tubulin, gamma 2 0.505537
RGPD3 RANBP2-like and GRIP domain containing 3 0.504724
TSKS testis-specific serine kinase substrate 0.503506
ZWINT ZW10 interacting kinetochore protein 0.501476
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.50107
STK26 serine/threonine protein kinase 26 0.500258
TSNAXIP1 translin-associated factor X interacting protein 1 0.499447
KIFC1 kinesin family member C1 0.498636
INVS inversin 0.498231
GMNN geminin, DNA replication inhibitor 0.497826
FBXW5 F-box and WD repeat domain containing 5 0.49742
ANKRD32 ankyrin repeat domain 32 0.49661
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.494585
RABGAP1 RAB GTPase activating protein 1 0.494585
CEP162 centrosomal protein 162kDa 0.49418
PARP1 poly (ADP-ribose) polymerase 1 0.493371
CENPF centromere protein F, 350/400kDa 0.490944
CCDC124 coiled-coil domain containing 124 0.488115
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.487711
LRRC45 leucine rich repeat containing 45 0.4865
CCDC141 coiled-coil domain containing 141 0.4865
EVI5 ecotropic viral integration site 5 0.485693
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.485693
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.485693
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.483273
AXIN1 axin 1 0.476429
TBCD tubulin folding cofactor D 0.476027
STK11 serine/threonine kinase 11 0.474018
CC2D2B coiled-coil and C2 domain containing 2B 0.471208
TPPP tubulin polymerization promoting protein 0.470005
CC2D2A coiled-coil and C2 domain containing 2A 0.468802
HAUS2 HAUS augmin-like complex, subunit 2 0.4676
CEP350 centrosomal protein 350kDa 0.4676
FMR1NB fragile X mental retardation 1 neighbor 0.4676
SHH sonic hedgehog 0.4676
NPHP3 nephronophthisis 3 (adolescent) 0.465198
SNORA29 small nucleolar RNA, H/ACA box 29 0.461998
WDR60 WD repeat domain 60 0.459203
FAM110A family with sequence similarity 110, member A 0.458006
FAM110B family with sequence similarity 110, member B 0.458006
SAV1 salvador family WW domain containing protein 1 0.456809
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.455214
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.45004
CDC14B cell division cycle 14B 0.449245
C10ORF90 chromosome 10 open reading frame 90 0.443292
CCNB2 cyclin B2 0.4425
CDC27 cell division cycle 27 0.44052
MZT2B mitotic spindle organizing protein 2B 0.439728
MZT2A mitotic spindle organizing protein 2A 0.439728
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.438542
SGOL2 shugoshin-like 2 (S. pombe) 0.438146
SPICE1 spindle and centriole associated protein 1 0.431829
WDR34 WD repeat domain 34 0.428678
ANKRD6 ankyrin repeat domain 6 0.424745
CHEK2 checkpoint kinase 2 0.423174
RUVBL1 RuvB-like AAA ATPase 1 0.421212
MCRS1 microspherule protein 1 0.420036
OLA1 Obg-like ATPase 1 0.419252
EPB41 erythrocyte membrane protein band 4.1 0.419252
FMNL1 formin-like 1 0.417685
KIAA0753 KIAA0753 0.417294
CCDC14 coiled-coil domain containing 14 0.417294
MID1 midline 1 0.416511
CCDC13 coiled-coil domain containing 13 0.414946
RANBP2 RAN binding protein 2 0.409089
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.408699
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.408699
TEKT1 tektin 1 0.40714
TTK TTK protein kinase 0.40675
KIF9 kinesin family member 9 0.405971
TBCC tubulin folding cofactor C 0.404415
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.400527
RB1 retinoblastoma 1 0.399363
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.399363
CCDC67 coiled-coil domain containing 67 0.398587
CCNA2 cyclin A2 0.397035
CASC1 cancer susceptibility candidate 1 0.395873
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.39471
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.394323
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.393936
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.393162
RANBP10 RAN binding protein 10 0.392001
CKAP2 cytoskeleton associated protein 2 0.390455
FGFR1 fibroblast growth factor receptor 1 0.390455
NUDCD2 NudC domain containing 2 0.389296
NME7 NME/NM23 family member 7 0.388909
NUP62 nucleoporin 62kDa 0.388137
LZTS2 leucine zipper, putative tumor suppressor 2 0.387751
APC adenomatous polyposis coli 0.387365
ERBB2 erb-b2 receptor tyrosine kinase 2 0.385822
LCA5 Leber congenital amaurosis 5 0.385822
FIGN fidgetin 0.381199
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.380045
KCTD17 potassium channel tetramerization domain containing 17 0.379276
PDE4DIP phosphodiesterase 4D interacting protein 0.379276
HSPB11 heat shock protein family B (small), member 11 0.378122
GSK3B glycogen synthase kinase 3 beta 0.376586
ZW10 zw10 kinetochore protein 0.376586
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.371982
MIS12 MIS12 kinetochore complex component 0.371599
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.370067
PARD3 par-3 family cell polarity regulator 0.369684
NDC80 NDC80 kinetochore complex component 0.368536
FBF1 Fas (TNFRSF6) binding factor 1 0.366241
CCND1 cyclin D1 0.366241
OBSL1 obscurin-like 1 0.364713
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.361659
HRAS Harvey rat sarcoma viral oncogene homolog 0.360515
RPGRIP1L RPGRIP1-like 0.360133
CENPL centromere protein L 0.360133
PDCD10 programmed cell death 10 0.357847
RANBP1 RAN binding protein 1 0.357467
DIAPH2 diaphanous-related formin 2 0.356705
AIDA axin interactor, dorsalization associated 0.356705
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 0.350243
ZBTB18 zinc finger and BTB domain containing 18 0.349863
SYNE2 spectrin repeat containing, nuclear envelope 2 0.348725
DIAPH1 diaphanous-related formin 1 0.347587
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.347208
SPEF1 sperm flagellar 1 0.346071
FAM110C family with sequence similarity 110, member C 0.346071
HYDIN HYDIN, axonemal central pair apparatus protein 0.344178
PARG poly (ADP-ribose) glycohydrolase 0.343799
MIR215 microRNA 215 0.343042
FMN1 formin 1 0.340395
STK24 serine/threonine kinase 24 0.338506
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.337751
PARD6G par-6 family cell polarity regulator gamma 0.336241
ILK integrin-linked kinase 0.333602
STK25 serine/threonine kinase 25 0.332472
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.330213
RACGAP1 Rac GTPase activating protein 1 0.329084
NOTCH1 notch 1 0.328708
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.325327
BBS5 Bardet-Biedl syndrome 5 0.324951
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.324201
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.322325
RASGEF1B RasGEF domain family, member 1B 0.321575
BBS7 Bardet-Biedl syndrome 7 0.321201
STK31 serine/threonine kinase 31 0.320077
USP9X ubiquitin specific peptidase 9, X-linked 0.319328
MAP1S microtubule-associated protein 1S 0.318953
DRC7 dynein regulatory complex subunit 7 0.318953
CDK4 cyclin-dependent kinase 4 0.315586
GLOD4 glyoxalase domain containing 4 0.314091
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.312597
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.312224
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.311851
KIF15 kinesin family member 15 0.311105
RBM8A RNA binding motif protein 8A 0.310358
PLXNA2 plexin A2 0.309613
ARL2 ADP-ribosylation factor-like 2 0.308494
TRAPPC3 trafficking protein particle complex 3 0.307749
YPEL1 yippee-like 1 (Drosophila) 0.307749
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.307004
TBC1D32 TBC1 domain family, member 32 0.305143
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 0.304399
ZBTB20 zinc finger and BTB domain containing 20 0.304027
LIMK1 LIM domain kinase 1 0.303655
GOLGA3 golgin A3 0.302912
MAP1B microtubule-associated protein 1B 0.302912
KIF3A kinesin family member 3A 0.302168
IFT54 intraflagellar transport 54 0.301054
RAB6C RAB6C, member RAS oncogene family 0.299197
ZMYND10 zinc finger, MYND-type containing 10 0.298455
PTEN phosphatase and tensin homolog 0.297713
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.297342
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.297342
CLASP2 cytoplasmic linker associated protein 2 0.29586
CLK2 CDC-like kinase 2 0.294007
SLK STE20-like kinase 0.293637
CCDC64 coiled-coil domain containing 64 0.292897
UXT ubiquitously-expressed, prefoldin-like chaperone 0.292897
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.292157
LATS1 large tumor suppressor kinase 1 0.290308
MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.289569
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.288829
ZBTB33 zinc finger and BTB domain containing 33 0.28846
TRIM69 tripartite motif containing 69 0.287352
MARK2 MAP/microtubule affinity-regulating kinase 2 0.287352
RNF146 ring finger protein 146 0.286614
FJX1 four jointed box 1 (Drosophila) 0.285507
MYO5A myosin VA (heavy chain 12, myoxin) 0.285138
CCDC110 coiled-coil domain containing 110 0.281453
TPPP3 tubulin polymerization-promoting protein family member 3 0.281085
TPGS1 tubulin polyglutamylase complex subunit 1 0.278141
PDE4D phosphodiesterase 4D, cAMP-specific 0.277774
HUNK hormonally up-regulated Neu-associated kinase 0.276304
PKN1 protein kinase N1 0.275936
GOLGA7 golgin A7 0.274468
TPP2 tripeptidyl peptidase II 0.274468
EFHC1 EF-hand domain (C-terminal) containing 1 0.274101
KIF1C kinesin family member 1C 0.273
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.272633
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.272267
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.2719
TCP10 t-complex 10 0.2708
TCP10L2 t-complex 10-like 2 0.2708
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.270434
SZRD1 SUZ RNA binding domain containing 1 0.268969
CCHCR1 coiled-coil alpha-helical rod protein 1 0.268237
AATF apoptosis antagonizing transcription factor 0.267871
PPP6C protein phosphatase 6, catalytic subunit 0.267139
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 0.266042
SIK2 salt-inducible kinase 2 0.265677
GLI3 GLI family zinc finger 3 0.264946
KIFC3 kinesin family member C3 0.263485
FBXL7 F-box and leucine-rich repeat protein 7 0.26239
WEE1 WEE1 G2 checkpoint kinase 0.261296
TSN translin 0.260202
PIBF1 progesterone immunomodulatory binding factor 1 0.260202
CEP41 centrosomal protein 41kDa 0.259837
NKTR natural killer cell triggering receptor 0.257289
RILPL1 Rab interacting lysosomal protein-like 1 0.255107
UVRAG UV radiation resistance associated 0.255107
MAP7D3 MAP7 domain containing 3 0.254743
CUL7 cullin 7 0.25438
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.253291
SAMD9 sterile alpha motif domain containing 9 0.252927
DUSP23 dual specificity phosphatase 23 0.252927
DIXDC1 DIX domain containing 1 0.251839
NUSAP1 nucleolar and spindle associated protein 1 0.251839
CDT1 chromatin licensing and DNA replication factor 1 0.251476
EMD emerin 0.251114
MKKS McKusick-Kaufman syndrome 0.251114
GORAB golgin, RAB6-interacting 0.250751
UBE2I ubiquitin-conjugating enzyme E2I 0.250389
STARD9 StAR-related lipid transfer (START) domain containing 9 0.249302
TSG101 tumor susceptibility 101 0.249302
RAN RAN, member RAS oncogene family 0.248216
NUDCD3 NudC domain containing 3 0.247492
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.24713
BRSK1 BR serine/threonine kinase 1 0.245323
AXIN2 axin 2 0.243879
PPP4R1 protein phosphatase 4, regulatory subunit 1 0.242437
TTLL12 tubulin tyrosine ligase-like family member 12 0.242437
PSKH1 protein serine kinase H1 0.242437
MPLKIP M-phase specific PLK1 interacting protein 0.242076
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.240996
TTC8 tetratricopeptide repeat domain 8 0.240996
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.240636
GLI2 GLI family zinc finger 2 0.240636
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.239557
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.238837
MTUS1 microtubule associated tumor suppressor 1 0.238119
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.236683
SAC3D1 SAC3 domain containing 1 0.235966
TSNAX translin-associated factor X 0.235966
SSTR3 somatostatin receptor 3 0.235249
TOPBP1 topoisomerase (DNA) II binding protein 1 0.233817
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 0.233101
PCID2 PCI domain containing 2 0.232386
CIB1 calcium and integrin binding 1 (calmyrin) 0.232029
DYNLL1 dynein, light chain, LC8-type 1 0.231672
HSPA8 heat shock 70kDa protein 8 0.231672
SYNE1 spectrin repeat containing, nuclear envelope 1 0.231315
RANBP9 RAN binding protein 9 0.230245
SIRT2 sirtuin 2 0.229532
FOXP2 forkhead box P2 0.228819
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.228464
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.228108
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.227041
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.225976
LZTFL1 leucine zipper transcription factor-like 1 0.224913
WASH7P WAS protein family homolog 7 pseudogene 0.224558
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.223497
SMO smoothened, frizzled class receptor 0.223143
UBE3A ubiquitin protein ligase E3A 0.222083
CDCA4 cell division cycle associated 4 0.22173
DVL1 dishevelled segment polarity protein 1 0.221378
WASH6P WAS protein family homolog 6 pseudogene 0.221378
SPATA4 spermatogenesis associated 4 0.220673
FBXL2 F-box and leucine-rich repeat protein 2 0.219969
PKD2L1 polycystic kidney disease 2-like 1 0.219617
WASH1 WAS protein family homolog 1 0.218914
FYN FYN proto-oncogene, Src family tyrosine kinase 0.218914
CHKA choline kinase alpha 0.217861
KLHL22 kelch-like family member 22 0.217861
DCAF12 DDB1 and CUL4 associated factor 12 0.21681
IFT52 intraflagellar transport 52 0.215412
STOML3 stomatin (EPB72)-like 3 0.214714
MASTL microtubule associated serine/threonine kinase-like 0.214366
CCNE1 cyclin E1 0.213322
ABLIM3 actin binding LIM protein family, member 3 0.211587
TCTN2 tectonic family member 2 0.210894
CYLD cylindromatosis (turban tumor syndrome) 0.210894
USP47 ubiquitin specific peptidase 47 0.209858
DVL2 dishevelled segment polarity protein 2 0.209169
MZT1 mitotic spindle organizing protein 1 0.208481
MEIG1 meiosis/spermiogenesis associated 1 0.208137
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.207794
CBY1 chibby homolog 1 (Drosophila) 0.207108
UBE3C ubiquitin protein ligase E3C 0.206423
TEKT3 tektin 3 0.205059
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.204718
CUL9 cullin 9 0.204718
RIC8A RIC8 guanine nucleotide exchange factor A 0.203361
MAGED2 melanoma antigen family D2 0.202346
UBE2H ubiquitin-conjugating enzyme E2H 0.202009
DCX doublecortin 0.202009
PROCR protein C receptor, endothelial 0.201672
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.200999
SACK1D scaffolding CK1 anchoring protein D 0.199659
DNM2 dynamin 2 0.199659
STK10 serine/threonine kinase 10 0.199325
MDM1 Mdm1 nuclear protein homolog (mouse) 0.198991
TSSK6 testis-specific serine kinase 6 0.197662
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.197662
SAMD9L sterile alpha motif domain containing 9-like 0.19733
GPR176 G protein-coupled receptor 176 0.196999
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.196999
GOLGA2 golgin A2 0.196669
KIF4A kinesin family member 4A 0.195353
DVL3 dishevelled segment polarity protein 3 0.194045
ATR ATR serine/threonine kinase 0.193719
MISP mitotic spindle positioning 0.19307
SUN5 Sad1 and UNC84 domain containing 5 0.192746
KIF12 kinesin family member 12 0.192423
E2F5 E2F transcription factor 5, p130-binding 0.191456
ECT2 epithelial cell transforming 2 0.189222
BUB3 BUB3 mitotic checkpoint protein 0.189222
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 0.188274
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.18796
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.18702
MYO5B myosin VB 0.186708
RAB11A RAB11A, member RAS oncogene family 0.186397
UBXN6 UBX domain protein 6 0.186397
ESR1 estrogen receptor 1 0.185777
PDE4B phosphodiesterase 4B, cAMP-specific 0.18516
WDR35 WD repeat domain 35 0.184853
PRC1 protein regulator of cytokinesis 1 0.184547
INF2 inverted formin, FH2 and WH2 domain containing 0.183935
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.183328
TRAPPC8 trafficking protein particle complex 8 0.183025
LMNA lamin A/C 0.182723
NEK11 NIMA-related kinase 11 0.182122
CASC5 cancer susceptibility candidate 5 0.180339
CDCA8 cell division cycle associated 8 0.180339
ANLN anillin, actin binding protein 0.179459
ANAPC13 anaphase promoting complex subunit 13 0.179459
EGFR epidermal growth factor receptor 0.178588
ZIC4 Zic family member 4 0.178299
CCDC151 coiled-coil domain containing 151 0.177724
DUS2 dihydrouridine synthase 2 0.17687
DST dystonin 0.175466
TELO2 telomere maintenance 2 0.174635
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 0.174087
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.173814
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.172735
ATXN10 ataxin 10 0.172735
PSEN1 presenilin 1 0.17141
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.170629
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.169099
SNX10 sorting nexin 10 0.168598
CBX5 chromobox homolog 5 0.167856
CTNND1 catenin (cadherin-associated protein), delta 1 0.166884
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.165231
ATL3 atlastin GTPase 3 0.164089
DAAM1 dishevelled associated activator of morphogenesis 1 0.163865
NUP188 nucleoporin 188kDa 0.16298
CDK6 cyclin-dependent kinase 6 0.16233
CDC6 cell division cycle 6 0.16233
BRSK2 BR serine/threonine kinase 2 0.161905
GPC2 glypican 2 0.161484
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.161068
MAK male germ cell-associated kinase 0.159658
TSPO translocator protein (18kDa) 0.159462
ZNF335 zinc finger protein 335 0.159074
GLIPR1 GLI pathogenesis-related 1 0.158882
MAGOHB mago-nashi homolog B (Drosophila) 0.157943
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 0.15776
HTT huntingtin 0.157578
CIB2 calcium and integrin binding family member 2 0.157578
CCNY cyclin Y 0.157397
RANGAP1 Ran GTPase activating protein 1 0.156513