centrosome Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. (Gene Ontology, GO_0005813)
External Link http://amigo.geneontology.org/amigo/term/GO:0005813
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Genes

386 proteins localized to the centrosome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AATF apoptosis antagonizing transcription factor
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
AHI1 Abelson helper integration site 1
AKAP9 A kinase (PRKA) anchor protein 9
ALMS1 Alstrom syndrome protein 1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKRD26 ankyrin repeat domain 26
ANKRD32 ankyrin repeat domain 32
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARL2 ADP-ribosylation factor-like 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARL3 ADP-ribosylation factor-like 3
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AUNIP aurora kinase A and ninein interacting protein
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
AXIN2 axin 2
B9D1 B9 protein domain 1
B9D2 B9 protein domain 2
BBS1 Bardet-Biedl syndrome 1
BBS4 Bardet-Biedl syndrome 4
BBS7 Bardet-Biedl syndrome 7
BCL2L1 BCL2-like 1
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2
BRCA2 breast cancer 2, early onset
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
C10ORF90 chromosome 10 open reading frame 90
C2CD3 C2 calcium-dependent domain containing 3
C7ORF31 chromosome 7 open reading frame 31
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAPRIN2 caprin family member 2
CCDC14 coiled-coil domain containing 14
CCDC15 coiled-coil domain containing 15
CCDC28B coiled-coil domain containing 28B
CCDC61 coiled-coil domain containing 61
CCDC64 coiled-coil domain containing 64
CCDC77 coiled-coil domain containing 77
CCDC8 coiled-coil domain containing 8
CCDC85B coiled-coil domain containing 85B
CCNB1 cyclin B1
CCNB2 cyclin B2
CCP110 centriolar coiled coil protein 110kDa
CCSAP centriole, cilia and spindle-associated protein
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDC14A cell division cycle 14A
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDC27 cell division cycle 27
CDC45 cell division cycle 45
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDK6 cyclin-dependent kinase 6
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CENPJ centromere protein J
CEP112 centrosomal protein 112kDa
CEP120 centrosomal protein 120kDa
CEP126 centrosomal protein 126kDa
CEP131 centrosomal protein 131kDa
CEP135 centrosomal protein 135kDa
CEP152 centrosomal protein 152kDa
CEP162 centrosomal protein 162kDa
CEP164 centrosomal protein 164kDa
CEP170 centrosomal protein 170kDa
CEP250 centrosomal protein 250kDa
CEP290 centrosomal protein 290kDa
CEP295 centrosomal protein 295kDa
CEP350 centrosomal protein 350kDa
CEP41 centrosomal protein 41kDa
CEP44 centrosomal protein 44kDa
CEP55 centrosomal protein 55kDa
CEP57 centrosomal protein 57kDa
CEP63 centrosomal protein 63kDa
CEP68 centrosomal protein 68kDa
CEP70 centrosomal protein 70kDa
CEP72 centrosomal protein 72kDa
CEP76 centrosomal protein 76kDa
CEP78 centrosomal protein 78kDa
CEP85 centrosomal protein 85kDa
CEP85L centrosomal protein 85kDa-like
CEP89 centrosomal protein 89kDa
CEP95 centrosomal protein 95kDa
CEP97 centrosomal protein 97kDa
CETN1 centrin, EF-hand protein, 1
CETN2 centrin, EF-hand protein, 2
CETN3 centrin, EF-hand protein, 3
CHD3 chromodomain helicase DNA binding protein 3
CHD4 chromodomain helicase DNA binding protein 4
CHEK1 checkpoint kinase 1
CIB1 calcium and integrin binding 1 (calmyrin)
CKAP2 cytoskeleton associated protein 2
CKAP2L cytoskeleton associated protein 2-like
CKAP5 cytoskeleton associated protein 5
CLASP1 cytoplasmic linker associated protein 1
CLIC4 chloride intracellular channel 4
CLIP1 CAP-GLY domain containing linker protein 1
CNTRL centriolin
CNTROB centrobin, centrosomal BRCA2 interacting protein
CROCC ciliary rootlet coiled-coil, rootletin
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSPP1 centrosome and spindle pole associated protein 1
CTAG2 cancer/testis antigen 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL7 cullin 7
CYLD cylindromatosis (turban tumor syndrome)
DCAF12 DDB1 and CUL4 associated factor 12
DCLRE1B DNA cross-link repair 1B
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DCTN4 dynactin 4 (p62)
DCTN5 dynactin 5 (p25)
DCTN6 dynactin 6
DDAH2 dimethylarginine dimethylaminohydrolase 2
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DISC1 disrupted in schizophrenia 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPF2 D4, zinc and double PHD fingers family 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DYNLRB1 dynein, light chain, roadblock-type 1
DZIP1 DAZ interacting zinc finger protein 1
EFHC1 EF-hand domain (C-terminal) containing 1
ELL2 elongation factor, RNA polymerase II, 2
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EYA2 EYA transcriptional coactivator and phosphatase 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM161A family with sequence similarity 161, member A
FBF1 Fas (TNFRSF6) binding factor 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXW11 F-box and WD repeat domain containing 11
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1OP FGFR1 oncogene partner
FOPNL FGFR1OP N-terminal like
G6PD glucose-6-phosphate dehydrogenase
GEN1 GEN1 Holliday junction 5' flap endonuclease
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GSG2 germ cell associated 2 (haspin)
GSK3B glycogen synthase kinase 3 beta
HARBI1 harbinger transposase derived 1
HAUS1 HAUS augmin-like complex, subunit 1
HAUS2 HAUS augmin-like complex, subunit 2
HAUS3 HAUS augmin-like complex, subunit 3
HAUS4 HAUS augmin-like complex, subunit 4
HAUS5 HAUS augmin-like complex, subunit 5
HAUS6 HAUS augmin-like complex, subunit 6
HAUS7 HAUS augmin-like complex, subunit 7
HAUS8 HAUS augmin-like complex, subunit 8
HEPACAM2 HEPACAM family member 2
HOOK2 hook microtubule-tethering protein 2
HOOK3 hook microtubule-tethering protein 3
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone
HSPB11 heat shock protein family B (small), member 11
HYLS1 hydrolethalus syndrome 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFT140 intraflagellar transport 140
IFT20 intraflagellar transport 20
IFT22 intraflagellar transport 22
IFT27 intraflagellar transport 27
IFT38 intraflagellar transport 38
IFT46 intraflagellar transport 46
IFT54 intraflagellar transport 54
IFT57 intraflagellar transport 57
IFT74 intraflagellar transport 74
IFT80 intraflagellar transport 80
IFT81 intraflagellar transport 81
IQCB1 IQ motif containing B1
IST1 increased sodium tolerance 1 homolog (yeast)
ITSN2 intersectin 2
JTB jumping translocation breakpoint
KATNA1 katanin p60 (ATPase containing) subunit A 1
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KIAA0368 KIAA0368
KIAA0586 KIAA0586
KIAA0753 KIAA0753
KIF13A kinesin family member 13A
KIF15 kinesin family member 15
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF2A kinesin heavy chain member 2A
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIFAP3 kinesin-associated protein 3
KIFC3 kinesin family member C3
KIZ kizuna centrosomal protein
KLHL21 kelch-like family member 21
KLHL22 kelch-like family member 22
LRRC45 leucine rich repeat containing 45
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LZTS2 leucine zipper, putative tumor suppressor 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAF1 MAF1 homolog (S. cerevisiae)
MAK male germ cell-associated kinase
MAP10 microtubule-associated protein 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP7D3 MAP7 domain containing 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK4 MAP/microtubule affinity-regulating kinase 4
MASTL microtubule associated serine/threonine kinase-like
MBNL1 muscleblind-like splicing regulator 1
MCM3 minichromosome maintenance complex component 3
MDH1 malate dehydrogenase 1, NAD (soluble)
MEAF6 MYST/Esa1-associated factor 6
MED12 mediator complex subunit 12
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKKS McKusick-Kaufman syndrome
MKS1 Meckel syndrome, type 1
MPHOSPH9 M-phase phosphoprotein 9
MPLKIP M-phase specific PLK1 interacting protein
MTUS2 microtubule associated tumor suppressor candidate 2
MVB12A multivesicular body subunit 12A
MYCBP MYC binding protein
MYO18B myosin XVIIIB
MZT1 mitotic spindle organizing protein 1
MZT2A mitotic spindle organizing protein 2A
MZT2B mitotic spindle organizing protein 2B
NCAPG non-SMC condensin I complex, subunit G
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NDN necdin, melanoma antigen (MAGE) family member
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK1 NIMA-related kinase 1
NEK2 NIMA-related kinase 2
NFE2L2 nuclear factor, erythroid 2-like 2
NIN ninein (GSK3B interacting protein)
NIT2 nitrilase family, member 2
NME7 NME/NM23 family member 7
NPHP4 nephronophthisis 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUBP2 nucleotide binding protein 2
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP107 nucleoporin 107kDa
OBSL1 obscurin-like 1
ODF2 outer dense fiber of sperm tails 2
ODF2L outer dense fiber of sperm tails 2-like
OFD1 oral-facial-digital syndrome 1
OLA1 Obg-like ATPase 1
ORC2 origin recognition complex, subunit 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCGF5 polycomb group ring finger 5
PCM1 pericentriolar material 1
PCNA proliferating cell nuclear antigen
PCNT pericentrin
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PIBF1 progesterone immunomodulatory binding factor 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKN2 protein kinase N2
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
POC1A POC1 centriolar protein A
POC1B POC1 centriolar protein B
POC5 POC5 centriolar protein
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R42 protein phosphatase 1, regulatory subunit 42
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PPP4R2 protein phosphatase 4, regulatory subunit 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROCR protein C receptor, endothelial
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB6C RAB6C, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RABL6 RAB, member RAS oncogene family-like 6
RAD51D RAD51 paralog D
RAP1GAP2 RAP1 GTPase activating protein 2
RAPSN receptor-associated protein of the synapse
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGCC regulator of cell cycle
RGS14 regulator of G-protein signaling 14
RIC8B RIC8 guanine nucleotide exchange factor B
RILPL1 Rab interacting lysosomal protein-like 1
RILPL2 Rab interacting lysosomal protein-like 2
RITA1 RBPJ interacting and tubulin associated 1
RMDN1 regulator of microtubule dynamics 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1L RPGRIP1-like
RPL32 ribosomal protein L32
SASS6 spindle assembly 6 homolog (C. elegans)
SCLT1 sodium channel and clathrin linker 1
SDCCAG8 serologically defined colon cancer antigen 8
SGOL1 shugoshin-like 1 (S. pombe)
SIRT2 sirtuin 2
SKI SKI proto-oncogene
SLAIN2 SLAIN motif family, member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD4 SMAD family member 4
SNAP29 synaptosomal-associated protein, 29kDa
SNX10 sorting nexin 10
SORBS1 sorbin and SH3 domain containing 1
SPAST spastin
SPATC1 spermatogenesis and centriole associated 1
SPICE1 spindle and centriole associated protein 1
SSNA1 Sjogren syndrome nuclear autoantigen 1
STIL SCL/TAL1 interrupting locus
STK26 serine/threonine protein kinase 26
SYTL4 synaptotagmin-like 4
TACC3 transforming, acidic coiled-coil containing protein 3
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
TCEA2 transcription elongation factor A (SII), 2
TCHP trichoplein, keratin filament binding
TCP1 t-complex 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM67 transmembrane protein 67
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOPBP1 topoisomerase (DNA) II binding protein 1
TPGS1 tubulin polyglutamylase complex subunit 1
TRAF5 TNF receptor-associated factor 5
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPYL2 TSPY-like 2
TTC19 tetratricopeptide repeat domain 19
TTC26 tetratricopeptide repeat domain 26
TTC28 tetratricopeptide repeat domain 28
TTC8 tetratricopeptide repeat domain 8
TTI2 TELO2 interacting protein 2
TTLL5 tubulin tyrosine ligase-like family member 5
TUBG1 tubulin, gamma 1
TUBGCP2 tubulin, gamma complex associated protein 2
TUBGCP3 tubulin, gamma complex associated protein 3
TUBGCP4 tubulin, gamma complex associated protein 4
TUBGCP5 tubulin, gamma complex associated protein 5
TUBGCP6 tubulin, gamma complex associated protein 6
TXNDC9 thioredoxin domain containing 9
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UNC119 unc-119 homolog (C. elegans)
USP2 ubiquitin specific peptidase 2
USP20 ubiquitin specific peptidase 20
USP33 ubiquitin specific peptidase 33
UXT ubiquitously-expressed, prefoldin-like chaperone
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WDR35 WD repeat domain 35
WRAP73 WD repeat containing, antisense to TP73
WRN Werner syndrome, RecQ helicase-like
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZFYVE19 zinc finger, FYVE domain containing 19
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF12 zinc finger protein 12
ZNF274 zinc finger protein 274
ZNF322 zinc finger protein 322