centrosome Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. (Gene Ontology, GO_0005813)
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Genes

207 genes co-occuring with the biological term centrosome in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP9 A kinase (PRKA) anchor protein 9
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALMS1 Alstrom syndrome protein 1
ARR3 arrestin 3, retinal (X-arrestin)
ARRB2 arrestin, beta 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKC aurora kinase C
AXIN1 axin 1
BICD1 bicaudal D homolog 1 (Drosophila)
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRSK1 BR serine/threonine kinase 1
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C14ORF166 chromosome 14 open reading frame 166
CCDC141 coiled-coil domain containing 141
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCP110 centriolar coiled coil protein 110kDa
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CDC25B cell division cycle 25B
CDC42 cell division cycle 42
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CENPJ centromere protein J
CEP126 centrosomal protein 126kDa
CEP131 centrosomal protein 131kDa
CEP152 centrosomal protein 152kDa
CEP192 centrosomal protein 192kDa
CEP55 centrosomal protein 55kDa
CEP63 centrosomal protein 63kDa
CEP68 centrosomal protein 68kDa
CEP72 centrosomal protein 72kDa
CETN2 centrin, EF-hand protein, 2
CHD3 chromodomain helicase DNA binding protein 3
CHD4 chromodomain helicase DNA binding protein 4
CHEK1 checkpoint kinase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CIB1 calcium and integrin binding 1 (calmyrin)
CKAP5 cytoskeleton associated protein 5
CLTC clathrin, heavy chain (Hc)
CLTCL1 clathrin, heavy chain-like 1
CNTRL centriolin
CNTROB centrobin, centrosomal BRCA2 interacting protein
CSNK1D casein kinase 1, delta
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCTN1 dynactin 1
DISC1 disrupted in schizophrenia 1
DLG1 discs, large homolog 1 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNM2 dynamin 2
DST dystonin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYNLL1 dynein, light chain, LC8-type 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
ELAVL1 ELAV like RNA binding protein 1
EMD emerin
EPB41 erythrocyte membrane protein band 4.1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESR1 estrogen receptor 1
EVI5 ecotropic viral integration site 5
FBXW5 F-box and WD repeat domain containing 5
FSD1 fibronectin type III and SPRY domain containing 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
GMNN geminin, DNA replication inhibitor
GOLGA2 golgin A2
GOLIM4 golgi integral membrane protein 4
GRK5 G protein-coupled receptor kinase 5
GSK3B glycogen synthase kinase 3 beta
HDAC8 histone deacetylase 8
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOOK2 hook microtubule-tethering protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA9 heat shock 70kDa protein 9 (mortalin)
HTT huntingtin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ILK integrin-linked kinase
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KIAA0101 KIAA0101
KIAA1524 KIAA1524
KIF11 kinesin family member 11
KIF13A kinesin family member 13A
KIF15 kinesin family member 15
KLF4 Kruppel-like factor 4 (gut)
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRC45 leucine rich repeat containing 45
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MCPH1 microcephalin 1
MCRS1 microspherule protein 1
MDC1 mediator of DNA-damage checkpoint 1
MECOM MDS1 and EVI1 complex locus
MKS1 Meckel syndrome, type 1
MST1 macrophage stimulating 1
MTA1 metastasis associated 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NBN nibrin
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG1 N-myc downstream regulated 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK2 NIMA-related kinase 2
NEK6 NIMA-related kinase 6
NEK7 NIMA-related kinase 7
NEK9 NIMA-related kinase 9
NEURL4 neuralized E3 ubiquitin protein ligase 4
NIN ninein (GSK3B interacting protein)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NQO1 NAD(P)H dehydrogenase, quinone 1
NSFL1C NSFL1 (p97) cofactor (p47)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUMA1 nuclear mitotic apparatus protein 1
NUP62 nucleoporin 62kDa
OAZ1 ornithine decarboxylase antizyme 1
ODF2 outer dense fiber of sperm tails 2
OLA1 Obg-like ATPase 1
ORC1 origin recognition complex, subunit 1
PARD6A par-6 family cell polarity regulator alpha
PCM1 pericentriolar material 1
PCNT pericentrin
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLEC plectin
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PML promyelocytic leukemia
PPA1 pyrophosphatase (inorganic) 1
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R42 protein phosphatase 1, regulatory subunit 42
PPP4C protein phosphatase 4, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTEN phosphatase and tensin homolog
RAB7A RAB7A, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RAD51B RAD51 paralog B
RAD51C RAD51 paralog C
RAN RAN, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RINT1 RAD50 interactor 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SASS6 spindle assembly 6 homolog (C. elegans)
SCYL1 SCY1-like 1 (S. cerevisiae)
SKP1 S-phase kinase-associated protein 1
SP1 Sp1 transcription factor
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
STK38 serine/threonine kinase 38
SUMO1 small ubiquitin-like modifier 1
SUN1 Sad1 and UNC84 domain containing 1
SUN2 Sad1 and UNC84 domain containing 2
TACC3 transforming, acidic coiled-coil containing protein 3
TCHP trichoplein, keratin filament binding
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TMEM67 transmembrane protein 67
TP53 tumor protein p53
TRIOBP TRIO and F-actin binding protein
TTK TTK protein kinase
TUBG1 tubulin, gamma 1
TUBGCP2 tubulin, gamma complex associated protein 2
TUBGCP3 tubulin, gamma complex associated protein 3
UBE3A ubiquitin protein ligase E3A
UBXN2B UBX domain protein 2B
USP33 ubiquitin specific peptidase 33
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
UXT ubiquitously-expressed, prefoldin-like chaperone
VDAC3 voltage-dependent anion channel 3
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR62 WD repeat domain 62
XPO1 exportin 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY1 YY1 transcription factor
ZBTB33 zinc finger and BTB domain containing 33
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF365 zinc finger protein 365