| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the cephaeline-3290 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ATF3 | activating transcription factor 3 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CCNL1 | cyclin L1 |
| CD83 | CD83 molecule |
| CDKN2AIP | CDKN2A interacting protein |
| CLK4 | CDC-like kinase 4 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTGF | connective tissue growth factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPHA2 | EPH receptor A2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| H2AFJ | H2A histone family, member J |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL32 | interleukin 32 |
| IL6 | interleukin 6 |
| IRF1 | interferon regulatory factor 1 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KLF10 | Kruppel-like factor 10 |
| LPXN | leupaxin |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NKX3-1 | NK3 homeobox 1 |
| PER1 | period circadian clock 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PSPC1 | paraspeckle component 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RND1 | Rho family GTPase 1 |
| S100A8 | S100 calcium binding protein A8 |
| SFPQ | splicing factor proline/glutamine-rich |
| SIRT4 | sirtuin 4 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNF | tumor necrosis factor |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF34 | zinc finger protein 34 |
| ZNF408 | zinc finger protein 408 |
| ZNF750 | zinc finger protein 750 |
| ZNF764 | zinc finger protein 764 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BCORL1 | BCL6 corepressor-like 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF216 | chromosome 1 open reading frame 216 |
| C5AR2 | complement component 5a receptor 2 |
| CBX6 | chromobox homolog 6 |
| CCNE1 | cyclin E1 |
| CCNG1 | cyclin G1 |
| CD302 | CD302 molecule |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CROT | carnitine O-octanoyltransferase |
| CRTAP | cartilage associated protein |
| CRYZ | crystallin, zeta (quinone reductase) |
| CSTA | cystatin A (stefin A) |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EGR3 | early growth response 3 |
| ENDOD1 | endonuclease domain containing 1 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FAM172A | family with sequence similarity 172, member A |
| FAM20B | family with sequence similarity 20, member B |
| FAM3C | family with sequence similarity 3, member C |
| FZD3 | frizzled class receptor 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| HECA | headcase homolog (Drosophila) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0232 | KIAA0232 |
| KIAA0754 | KIAA0754 |
| LBR | lamin B receptor |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LOC100272216 | uncharacterized LOC100272216 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP6D1 | MAP6 domain containing 1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| METTL21B | methyltransferase like 21B |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| OPN3 | opsin 3 |
| OTUD3 | OTU deubiquitinase 3 |
| PCDHB8 | protocadherin beta 8 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G12A | phospholipase A2, group XIIA |
| PMP22 | peripheral myelin protein 22 |
| PRKX | protein kinase, X-linked |
| PRSS23 | protease, serine, 23 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB3A | RAB3A, member RAS oncogene family |
| RUFY2 | RUN and FYVE domain containing 2 |
| SACS | sacsin molecular chaperone |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERINC5 | serine incorporator 5 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| TBC1D16 | TBC1 domain family, member 16 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPAN5 | tetraspanin 5 |
| UBL3 | ubiquitin-like 3 |
| VGF | VGF nerve growth factor inducible |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF516 | zinc finger protein 516 |