cephaeline-3290 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the cephaeline-3290 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
C17ORF53 chromosome 17 open reading frame 53
CCNL1 cyclin L1
CD83 CD83 molecule
CDKN2AIP CDKN2A interacting protein
CLK4 CDC-like kinase 4
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHA2 EPH receptor A2
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
H2AFJ H2A histone family, member J
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BF histone cluster 1, H2bf
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST1H4C histone cluster 1, H4c
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL32 interleukin 32
IL6 interleukin 6
IRF1 interferon regulatory factor 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF10 Kruppel-like factor 10
LPXN leupaxin
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-1 NK3 homeobox 1
PER1 period circadian clock 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSPC1 paraspeckle component 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
S100A8 S100 calcium binding protein A8
SFPQ splicing factor proline/glutamine-rich
SIRT4 sirtuin 4
SLC16A6 solute carrier family 16, member 6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPRY4 sprouty homolog 4 (Drosophila)
STYK1 serine/threonine/tyrosine kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNF tumor necrosis factor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ZMYM5 zinc finger, MYM-type 5
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF750 zinc finger protein 750
ZNF764 zinc finger protein 764
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ADGRA3 adhesion G protein-coupled receptor A3
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AMIGO2 adhesion molecule with Ig-like domain 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCORL1 BCL6 corepressor-like 1
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF216 chromosome 1 open reading frame 216
C5AR2 complement component 5a receptor 2
CBX6 chromobox homolog 6
CCNE1 cyclin E1
CCNG1 cyclin G1
CD302 CD302 molecule
CDC50A cell division cycle 50 P4-ATPase accessory subunit A
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CROT carnitine O-octanoyltransferase
CRTAP cartilage associated protein
CRYZ crystallin, zeta (quinone reductase)
CSTA cystatin A (stefin A)
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR3 early growth response 3
ENDOD1 endonuclease domain containing 1
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM114A1 family with sequence similarity 114, member A1
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FAM3C family with sequence similarity 3, member C
FZD3 frizzled class receptor 3
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GNPDA1 glucosamine-6-phosphate deaminase 1
HECA headcase homolog (Drosophila)
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KIAA0232 KIAA0232
KIAA0754 KIAA0754
LBR lamin B receptor
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOC100272216 uncharacterized LOC100272216
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRP3 low density lipoprotein receptor-related protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP6D1 MAP6 domain containing 1
MAT2A methionine adenosyltransferase II, alpha
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCM3AP-AS1 MCM3AP antisense RNA 1
METTL21B methyltransferase like 21B
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
OPN3 opsin 3
OTUD3 OTU deubiquitinase 3
PCDHB8 protocadherin beta 8
PCDHGB5 protocadherin gamma subfamily B, 5
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G12A phospholipase A2, group XIIA
PMP22 peripheral myelin protein 22
PRKX protein kinase, X-linked
PRSS23 protease, serine, 23
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB3A RAB3A, member RAS oncogene family
RUFY2 RUN and FYVE domain containing 2
SACS sacsin molecular chaperone
SCD5 stearoyl-CoA desaturase 5
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERINC5 serine incorporator 5
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SND1-IT1 SND1 intronic transcript 1
SNHG3 small nucleolar RNA host gene 3
SNORA21 small nucleolar RNA, H/ACA box 21
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
TBC1D16 TBC1 domain family, member 16
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN5 tetraspanin 5
UBL3 ubiquitin-like 3
VGF VGF nerve growth factor inducible
ZBTB44 zinc finger and BTB domain containing 44
ZMAT3 zinc finger, matrin-type 3
ZNF516 zinc finger protein 516