cephaeline-5612 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cephaeline-5612 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BIRC3 baculoviral IAP repeat containing 3
C2CD2L C2CD2-like
CCL2 chemokine (C-C motif) ligand 2
CCNL1 cyclin L1
CD83 CD83 molecule
CDKN2AIP CDKN2A interacting protein
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DPY19L2P2 DPY19L2 pseudogene 2
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
ENO3 enolase 3 (beta, muscle)
EPHA2 EPH receptor A2
FOS FBJ murine osteosarcoma viral oncogene homolog
FSTL3 follistatin-like 3 (secreted glycoprotein)
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
H2AFJ H2A histone family, member J
HES1 hes family bHLH transcription factor 1
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H4C histone cluster 1, H4c
HIST1H4H histone cluster 1, H4h
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL32 interleukin 32
IL6 interleukin 6
IRF1 interferon regulatory factor 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KDM6B lysine (K)-specific demethylase 6B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
LRP5L low density lipoprotein receptor-related protein 5-like
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-1 NK3 homeobox 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PER1 period circadian clock 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAU plasminogen activator, urokinase
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSPC1 paraspeckle component 1
RAD52 RAD52 homolog (S. cerevisiae)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
SERTAD3 SERTA domain containing 3
SIRT4 sirtuin 4
SLC16A6 solute carrier family 16, member 6
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SOCS2 suppressor of cytokine signaling 2
SPRY4 sprouty homolog 4 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST7L suppression of tumorigenicity 7 like
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNF tumor necrosis factor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPRA1 transmembrane protein, adipocyte asscociated 1
TXNIP thioredoxin interacting protein
VIPR1 vasoactive intestinal peptide receptor 1
ZNF16 zinc finger protein 16
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF419 zinc finger protein 419
ZNF442 zinc finger protein 442
ZNF764 zinc finger protein 764

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ADGRA3 adhesion G protein-coupled receptor A3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BTF3P11 basic transcription factor 3 pseudogene 11
CBX6 chromobox homolog 6
CCDC134 coiled-coil domain containing 134
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNG1 cyclin G1
CD302 CD302 molecule
CFD complement factor D (adipsin)
CGREF1 cell growth regulator with EF-hand domain 1
CPNE7 copine VII
CRLF1 cytokine receptor-like factor 1
CROT carnitine O-octanoyltransferase
CSTA cystatin A (stefin A)
CTSC cathepsin C
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR3 early growth response 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM114A1 family with sequence similarity 114, member A1
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FAM3C family with sequence similarity 3, member C
FBXO22 F-box protein 22
FRMD1 FERM domain containing 1
GFI1 growth factor independent 1 transcription repressor
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR27 G protein-coupled receptor 27
GRPR gastrin-releasing peptide receptor
HPN hepsin
HSPA8 heat shock 70kDa protein 8
INSIG1 insulin induced gene 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
LBR lamin B receptor
MAT2A methionine adenosyltransferase II, alpha
MBNL3 muscleblind-like splicing regulator 3
MCM3AP-AS1 MCM3AP antisense RNA 1
MEGF9 multiple EGF-like-domains 9
MRPL41 mitochondrial ribosomal protein L41
MUC3A mucin 3A, cell surface associated
NCS1 neuronal calcium sensor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NMU neuromedin U
OPN3 opsin 3
PADI1 peptidyl arginine deiminase, type I
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDZD8 PDZ domain containing 8
PHC3 polyhomeotic homolog 3 (Drosophila)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMP22 peripheral myelin protein 22
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKX protein kinase, X-linked
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
QSER1 glutamine and serine rich 1
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFXAP regulatory factor X-associated protein
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SACS sacsin molecular chaperone
SERINC5 serine incorporator 5
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SND1-IT1 SND1 intronic transcript 1
SNHG3 small nucleolar RNA host gene 3
SNORA21 small nucleolar RNA, H/ACA box 21
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRD5A3 steroid 5 alpha-reductase 3
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
SYNC syncoilin, intermediate filament protein
TGFBR1 transforming growth factor, beta receptor 1
TRIB2 tribbles pseudokinase 2
UBL3 ubiquitin-like 3
UNKL unkempt family zinc finger-like
VASH1 vasohibin 1
VASH2 vasohibin 2
YIPF4 Yip1 domain family, member 4
ZBTB44 zinc finger and BTB domain containing 44
ZMAT3 zinc finger, matrin-type 3
ZNF286A zinc finger protein 286A
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516