cerivastatin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. (Chemical Entities of Biological Interest Ontology, CHEBI_3558)
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Genes

2 genes co-occuring with the biological term cerivastatin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
C5 complement component 5
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase