| Dataset | Guide to Pharmacology Chemical Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (chemical) |
| Description | (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. (Chemical Entities of Biological Interest Ontology, CHEBI_3558) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2950 |
| Similar Terms | |
| Downloads & Tools |
1 receptors of the cerivastatin ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
| Symbol | Name |
|---|---|
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |