| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cetirizine-2468 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACAN | aggrecan |
| ADCK4 | aarF domain containing kinase 4 |
| ADRB3 | adrenoceptor beta 3 |
| ATN1 | atrophin 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA9 | carbonic anhydrase IX |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALB2 | calbindin 2 |
| CAMKV | CaM kinase-like vesicle-associated |
| CCDC64 | coiled-coil domain containing 64 |
| CFAP70 | cilia and flagella associated protein 70 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL13A1 | collagen, type XIII, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DAPK2 | death-associated protein kinase 2 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FGF12 | fibroblast growth factor 12 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ11292 | |
| FOXC2 | forkhead box C2 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GAST | gastrin |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HDLBP | high density lipoprotein binding protein |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGHD | immunoglobulin heavy constant delta |
| IL12A | interleukin 12A |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF26B | kinesin family member 26B |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLHL36 | kelch-like family member 36 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMD1 | LIM domains containing 1 |
| LMF1 | lipase maturation factor 1 |
| LMTK2 | lemur tyrosine kinase 2 |
| LRRC6 | leucine rich repeat containing 6 |
| LRRC75B | leucine rich repeat containing 75B |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LTK | leukocyte receptor tyrosine kinase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MMP1 | matrix metallopeptidase 1 |
| MYO1E | myosin IE |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NTF3 | neurotrophin 3 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUP88 | nucleoporin 88kDa |
| OMG | oligodendrocyte myelin glycoprotein |
| PON3 | paraoxonase 3 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PXN | paxillin |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB6A | RAB6A, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPLP2 | ribosomal protein, large, P2 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| S100A11 | S100 calcium binding protein A11 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SLAMF7 | SLAM family member 7 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SOCS2 | suppressor of cytokine signaling 2 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SSH3 | slingshot protein phosphatase 3 |
| SULF1 | sulfatase 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYT5 | synaptotagmin V |
| TFF2 | trefoil factor 2 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRIM10 | tripartite motif containing 10 |
| VPS9D1 | VPS9 domain containing 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARMC6 | armadillo repeat containing 6 |
| ARMC7 | armadillo repeat containing 7 |
| AXIN1 | axin 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLEC2D | C-type lectin domain family 2, member D |
| COQ3 | coenzyme Q3 methyltransferase |
| CRY2 | cryptochrome circadian clock 2 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNM3 | dynamin 3 |
| DOK3 | docking protein 3 |
| DPEP2 | dipeptidase 2 |
| EGR3 | early growth response 3 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FBXO31 | F-box protein 31 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FCHO1 | FCH domain only 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXD1 | forkhead box D1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GK3P | glycerol kinase 3 pseudogene |
| GRAMD1B | GRAM domain containing 1B |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA5 | homeobox A5 |
| IRS1 | insulin receptor substrate 1 |
| JMJD4 | jumonji domain containing 4 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAK | male germ cell-associated kinase |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MRAS | muscle RAS oncogene homolog |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCKAP1L | NCK-associated protein 1-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PITX2 | paired-like homeodomain 2 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR14L | proline rich 14-like |
| PRR7 | proline rich 7 (synaptic) |
| QPRT | quinolinate phosphoribosyltransferase |
| RAB23 | RAB23, member RAS oncogene family |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| REC8 | REC8 meiotic recombination protein |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFPL1S | RFPL1 antisense RNA 1 |
| RGS13 | regulator of G-protein signaling 13 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RWDD2A | RWD domain containing 2A |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIRT6 | sirtuin 6 |
| SLC12A9 | solute carrier family 12, member 9 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRABD | TraB domain containing |
| TRAIP | TRAF interacting protein |
| TRIM68 | tripartite motif containing 68 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC4 | tetratricopeptide repeat domain 4 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| XAB2 | XPA binding protein 2 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF350 | zinc finger protein 350 |
| ZNF696 | zinc finger protein 696 |
| ZNF862 | zinc finger protein 862 |
