cetirizine-2829 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cetirizine-2829 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEBP1 AE binding protein 1
AFAP1 actin filament associated protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AMPD1 adenosine monophosphate deaminase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATM ATM serine/threonine kinase
C8A complement component 8, alpha polypeptide
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CDC25C cell division cycle 25C
CFAP70 cilia and flagella associated protein 70
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CRHR1 corticotropin releasing hormone receptor 1
CROCC ciliary rootlet coiled-coil, rootletin
CSF1R colony stimulating factor 1 receptor
DLK2 delta-like 2 homolog (Drosophila)
ELSPBP1 epididymal sperm binding protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPOR erythropoietin receptor
EZR ezrin
FGF13 fibroblast growth factor 13
FLOT1 flotillin 1
FURIN furin (paired basic amino acid cleaving enzyme)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GREB1 growth regulation by estrogen in breast cancer 1
GRM7 glutamate receptor, metabotropic 7
HDAC5 histone deacetylase 5
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXA10 homeobox A10
HPX hemopexin
IDS iduronate 2-sulfatase
IFT38 intraflagellar transport 38
IGFBP5 insulin-like growth factor binding protein 5
ITPKA inositol-trisphosphate 3-kinase A
JUN jun proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
KDM8 lysine (K)-specific demethylase 8
MED13L mediator complex subunit 13-like
MED18 mediator complex subunit 18
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MST1 macrophage stimulating 1
N4BP1 NEDD4 binding protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NNAT neuronatin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
ONECUT2 one cut homeobox 2
PCM1 pericentriolar material 1
PCNX pecanex homolog (Drosophila)
PDGFB platelet-derived growth factor beta polypeptide
PHF20L1 PHD finger protein 20-like 1
PKNOX1 PBX/knotted 1 homeobox 1
POFUT1 protein O-fucosyltransferase 1
POU2F2 POU class 2 homeobox 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RBPMS RNA binding protein with multiple splicing
RELN reelin
RETN resistin
RNFT1 ring finger protein, transmembrane 1
ROM1 retinal outer segment membrane protein 1
RPL23AP53 ribosomal protein L23a pseudogene 53
SBNO1 strawberry notch homolog 1 (Drosophila)
SGK2 serum/glucocorticoid regulated kinase 2
SH2D3A SH2 domain containing 3A
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNRK SNF related kinase
SORBS1 sorbin and SH3 domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRSF5 serine/arginine-rich splicing factor 5
SRSF7 serine/arginine-rich splicing factor 7
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAAR5 trace amine associated receptor 5
UHRF1BP1L UHRF1 binding protein 1-like
UPP1 uridine phosphorylase 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WNK1 WNK lysine deficient protein kinase 1
WSCD1 WSC domain containing 1
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF419 zinc finger protein 419
ZNF484 zinc finger protein 484
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
ANKRD36 ankyrin repeat domain 36
ASB9 ankyrin repeat and SOCS box containing 9
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BPGM 2,3-bisphosphoglycerate mutase
BPHL biphenyl hydrolase-like (serine hydrolase)
BRIX1 BRX1, biogenesis of ribosomes
C1ORF159 chromosome 1 open reading frame 159
CBX4 chromobox homolog 4
CCDC91 coiled-coil domain containing 91
CEP97 centrosomal protein 97kDa
CISH cytokine inducible SH2-containing protein
CORT cortistatin
CRY1 cryptochrome circadian clock 1
CUEDC2 CUE domain containing 2
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FKBPL FK506 binding protein like
GLI3 GLI family zinc finger 3
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2L G patch domain containing 2-like
GSTCD glutathione S-transferase, C-terminal domain containing
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC11 histone deacetylase 11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFI35 interferon-induced protein 35
IGFLR1 IGF-like family receptor 1
IQCG IQ motif containing G
IRF9 interferon regulatory factor 9
JMJD4 jumonji domain containing 4
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
LIG4 ligase IV, DNA, ATP-dependent
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5 low density lipoprotein receptor-related protein 5
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MIS18BP1 MIS18 binding protein 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR6 myotubularin related protein 6
NCAPD3 non-SMC condensin II complex, subunit D3
NCS1 neuronal calcium sensor 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEU1 sialidase 1 (lysosomal sialidase)
NPM3 nucleophosmin/nucleoplasmin 3
NRBF2 nuclear receptor binding factor 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB8 protocadherin beta 8
PLA2G12A phospholipase A2, group XIIA
PLA2G3 phospholipase A2, group III
PMM1 phosphomannomutase 1
POLH polymerase (DNA directed), eta
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPH peripherin
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB5C RAB5C, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RBM41 RNA binding motif protein 41
RHOF ras homolog family member F (in filopodia)
RIBC2 RIB43A domain with coiled-coils 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SP1 Sp1 transcription factor
SPATA7 spermatogenesis associated 7
STARD5 StAR-related lipid transfer (START) domain containing 5
TDRD1 tudor domain containing 1
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
YEATS4 YEATS domain containing 4
ZBTB48 zinc finger and BTB domain containing 48
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF492 zinc finger protein 492