| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cetirizine-4231 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACOT11 | acyl-CoA thioesterase 11 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| AFF2 | AF4/FMR2 family, member 2 |
| APOA4 | apolipoprotein A-IV |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| AQP4 | aquaporin 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CALB2 | calbindin 2 |
| CASR | calcium-sensing receptor |
| CDH19 | cadherin 19, type 2 |
| COLEC11 | collectin sub-family member 11 |
| DCLK2 | doublecortin-like kinase 2 |
| DMWD | dystrophia myotonica, WD repeat containing |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM174B | family with sequence similarity 174, member B |
| FGFR2 | fibroblast growth factor receptor 2 |
| FOXP3 | forkhead box P3 |
| FZD5 | frizzled class receptor 5 |
| GABRA3 | gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
| GAS1 | growth arrest-specific 1 |
| GPATCH4 | G patch domain containing 4 |
| GPR63 | G protein-coupled receptor 63 |
| HFE | hemochromatosis |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXB3 | homeobox B3 |
| HPSE2 | heparanase 2 (inactive) |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IQCA1 | IQ motif containing with AAA domain 1 |
| ITGB8 | integrin, beta 8 |
| KIF25 | kinesin family member 25 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC75B | leucine rich repeat containing 75B |
| LY9 | lymphocyte antigen 9 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAP2 | microtubule-associated protein 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MMP3 | matrix metallopeptidase 3 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| NCAM1 | neural cell adhesion molecule 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPR1 | natriuretic peptide receptor 1 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NRF1 | nuclear respiratory factor 1 |
| OCM2 | oncomodulin 2 |
| OMD | osteomodulin |
| PACRG | PARK2 co-regulated |
| PCDH17 | protocadherin 17 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PGP | phosphoglycolate phosphatase |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIPOX | pipecolic acid oxidase |
| PLA2G5 | phospholipase A2, group V |
| PRDM14 | PR domain containing 14 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTRF | polymerase I and transcript release factor |
| RAB6B | RAB6B, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RGS5 | regulator of G-protein signaling 5 |
| RHCE | Rh blood group, CcEe antigens |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND2 | Rho family GTPase 2 |
| RNF17 | ring finger protein 17 |
| SAMD4B | sterile alpha motif domain containing 4B |
| SFRP5 | secreted frizzled-related protein 5 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SMAD6 | SMAD family member 6 |
| SNX29 | sorting nexin 29 |
| TLE2 | transducin-like enhancer of split 2 |
| TMOD1 | tropomodulin 1 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM3 | tripartite motif containing 3 |
| TRIM48 | tripartite motif containing 48 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| WDR55 | WD repeat domain 55 |
| ZNF154 | zinc finger protein 154 |
| ZNF24 | zinc finger protein 24 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AIM2 | absent in melanoma 2 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANXA10 | annexin A10 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBR4 | carbonyl reductase 4 |
| CCS | copper chaperone for superoxide dismutase |
| CD82 | CD82 molecule |
| CES3 | carboxylesterase 3 |
| CLDN1 | claudin 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNM3 | dynamin 3 |
| EDN1 | endothelin 1 |
| EHF | ets homologous factor |
| ERCC4 | excision repair cross-complementation group 4 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GPX2 | glutathione peroxidase 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H2BO | histone cluster 1, H2bo |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT54 | intraflagellar transport 54 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIF13B | kinesin family member 13B |
| KLHL25 | kelch-like family member 25 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT86 | keratin 86, type II |
| LATS1 | large tumor suppressor kinase 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| LRRC61 | leucine rich repeat containing 61 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAX9 | paired box 9 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE8B | phosphodiesterase 8B |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLAC8 | placenta-specific 8 |
| PODNL1 | podocan-like 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR4 | proline rich 4 (lacrimal) |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SP1 | Sp1 transcription factor |
| STAG3 | stromal antigen 3 |
| THAP7 | THAP domain containing 7 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM242 | transmembrane protein 242 |
| TOM1 | target of myb1 (chicken) |
| TRAC | T cell receptor alpha constant |
| TRAPPC13 | trafficking protein particle complex 13 |
| VASP | vasodilator-stimulated phosphoprotein |
| VN1R1 | vomeronasal 1 receptor 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZNF492 | zinc finger protein 492 |
