| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the cetirizine-4815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACVR1B | activin A receptor, type IB |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM29 | ADAM metallopeptidase domain 29 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALOX5 | arachidonate 5-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| AQP4 | aquaporin 4 |
| ATXN2L | ataxin 2-like |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP1 | bone morphogenetic protein 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CADM4 | cell adhesion molecule 4 |
| CCDC85B | coiled-coil domain containing 85B |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFAP45 | cilia and flagella associated protein 45 |
| COL5A2 | collagen, type V, alpha 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DBF4B | DBF4 zinc finger B |
| DMWD | dystrophia myotonica, WD repeat containing |
| DOCK5 | dedicator of cytokinesis 5 |
| EMC1 | ER membrane protein complex subunit 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ETV4 | ets variant 4 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBLN1 | fibulin 1 |
| FBXO9 | F-box protein 9 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GRAMD1C | GRAM domain containing 1C |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H1E | histone cluster 1, H1e |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDS | iduronate 2-sulfatase |
| IFFO1 | intermediate filament family orphan 1 |
| IFT54 | intraflagellar transport 54 |
| IL18 | interleukin 18 |
| LIF | leukemia inhibitory factor |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| MED18 | mediator complex subunit 18 |
| MEF2D | myocyte enhancer factor 2D |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MR1 | major histocompatibility complex, class I-related |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MST1 | macrophage stimulating 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF2 | neurofibromin 2 (merlin) |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NOL10 | nucleolar protein 10 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NREP | neuronal regeneration related protein |
| OCA2 | oculocutaneous albinism II |
| PARVA | parvin, alpha |
| PCDHA5 | protocadherin alpha 5 |
| PDLIM5 | PDZ and LIM domain 5 |
| PLAC4 | placenta-specific 4 |
| PLAU | plasminogen activator, urokinase |
| PLEK | pleckstrin |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLXDC1 | plexin domain containing 1 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RGS4 | regulator of G-protein signaling 4 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SERHL2 | serine hydrolase-like 2 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM10 | tripartite motif containing 10 |
| TTC38 | tetratricopeptide repeat domain 38 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZFP30 | ZFP30 zinc finger protein |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| AKTIP | AKT interacting protein |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BIN3 | bridging integrator 3 |
| BSG | basigin (Ok blood group) |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CD302 | CD302 molecule |
| CDCA3 | cell division cycle associated 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLDND1 | claudin domain containing 1 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CORO1A | coronin, actin binding protein, 1A |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSD | cathepsin D |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDA1 | DET1 and DDB1 associated 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNMBP | dynamin binding protein |
| DOC2A | double C2-like domains, alpha |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| FAM169A | family with sequence similarity 169, member A |
| FBXO31 | F-box protein 31 |
| FLT4 | fms-related tyrosine kinase 4 |
| FMO4 | flavin containing monooxygenase 4 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HIST1H2BI | histone cluster 1, H2bi |
| HPSE | heparanase |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INO80D | INO80 complex subunit D |
| INTS9 | integrator complex subunit 9 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| LAMB3 | laminin, beta 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIN7B | lin-7 homolog B (C. elegans) |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MED9 | mediator complex subunit 9 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NPY5R | neuropeptide Y receptor Y5 |
| NRSN2 | neurensin 2 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLXNA3 | plexin A3 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme |
| PRCP | prolylcarboxypeptidase (angiotensinase C) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RASA2 | RAS p21 protein activator 2 |
| RNF141 | ring finger protein 141 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| S100A4 | S100 calcium binding protein A4 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETX | senataxin |
| SIX1 | SIX homeobox 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TAGLN | transgelin |
| TBC1D19 | TBC1 domain family, member 19 |
| TCTN1 | tectonic family member 1 |
| TDRD7 | tudor domain containing 7 |
| TLR5 | toll-like receptor 5 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBXN6 | UBX domain protein 6 |
| URM1 | ubiquitin related modifier 1 |
| USB1 | U6 snRNA biogenesis 1 |
| YIPF5 | Yip1 domain family, member 5 |
| ZNF446 | zinc finger protein 446 |
| ZNF557 | zinc finger protein 557 |
| ZNF586 | zinc finger protein 586 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| ZW10 | zw10 kinetochore protein |
