chagas disease Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis. (Human Disease Ontology, DOID_12140)
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Genes

9 genes associated with the disease chagas disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL10 interleukin 10
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
TNF tumor necrosis factor