chemical Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

219 genes co-occuring with the biological term chemical in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACLY ATP citrate lyase
ADAM17 ADAM metallopeptidase domain 17
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADM adrenomedullin
AHR aryl hydrocarbon receptor
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ARG1 arginase 1
ATF3 activating transcription factor 3
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN3 ataxin 3
AVPR2 arginine vasopressin receptor 2
BAG1 BCL2-associated athanogene
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPN2 calpain 2, (m/II) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBS cystathionine-beta-synthase
CCKBR cholecystokinin B receptor
CCNB1 cyclin B1
CCR7 chemokine (C-C motif) receptor 7
CD44 CD44 molecule (Indian blood group)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRM3 cholinergic receptor, muscarinic 3
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CLCN1 chloride channel, voltage-sensitive 1
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CNR2 cannabinoid receptor 2 (macrophage)
CRYAA crystallin, alpha A
CRYGD crystallin, gamma D
CSK c-src tyrosine kinase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DHDH dihydrodiol dehydrogenase (dimeric)
DICER1 dicer 1, ribonuclease type III
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNM1 dynamin 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERO1L ERO1-like (S. cerevisiae)
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FASLG Fas ligand (TNF superfamily, member 6)
FFAR2 free fatty acid receptor 2
FFAR3 free fatty acid receptor 3
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
FXN frataxin
FYN FYN proto-oncogene, Src family tyrosine kinase
GAP43 growth associated protein 43
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCDH glutaryl-CoA dehydrogenase
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GJB1 gap junction protein, beta 1, 32kDa
GLA galactosidase, alpha
GLRA1 glycine receptor, alpha 1
GNRHR gonadotropin-releasing hormone receptor
GPBAR1 G protein-coupled bile acid receptor 1
GPR55 G protein-coupled receptor 55
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
HBP1 HMG-box transcription factor 1
HDAC3 histone deacetylase 3
HMGB1 high mobility group box 1
HNF4A hepatocyte nuclear factor 4, alpha
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRAS Harvey rat sarcoma viral oncogene homolog
HRH3 histamine receptor H3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSF1 heat shock transcription factor 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IAPP islet amyloid polypeptide
IL13 interleukin 13
IL18 interleukin 18
IL4 interleukin 4
IL6 interleukin 6
INS insulin
ISCU iron-sulfur cluster assembly enzyme
ITGB5 integrin, beta 5
JAK2 Janus kinase 2
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM3A lysine (K)-specific demethylase 3A
KLK7 kallikrein-related peptidase 7
LGALS4 lectin, galactoside-binding, soluble, 4
LGALS8 lectin, galactoside-binding, soluble, 8
LOX lysyl oxidase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MCOLN2 mucolipin 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLNR motilin receptor
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO1C myosin IC
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NOS2 nitric oxide synthase 2, inducible
NR1I3 nuclear receptor subfamily 1, group I, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OBP2A odorant binding protein 2A
OPRK1 opioid receptor, kappa 1
ORAI3 ORAI calcium release-activated calcium modulator 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARP1 poly (ADP-ribose) polymerase 1
PDIA2 protein disulfide isomerase family A, member 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGRMC1 progesterone receptor membrane component 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLN phospholamban
PML promyelocytic leukemia
POLB polymerase (DNA directed), beta
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKCE protein kinase C, epsilon
PRNP prion protein
PTBP1 polypyrimidine tract binding protein 1
PXN paxillin
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
REG4 regenerating islet-derived family, member 4
RHO rhodopsin
RPA1 replication protein A1, 70kDa
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCLY selenocysteine lyase
SCN9A sodium channel, voltage gated, type IX alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUMO1 small ubiquitin-like modifier 1
TF transferrin
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNS2 tensin 2
TP53 tumor protein p53
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB1 tribbles pseudokinase 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TXN thioredoxin
UBB ubiquitin B
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UMOD uromodulin
UNG uracil-DNA glycosylase
USP33 ubiquitin specific peptidase 33
UTRN utrophin
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VIPR1 vasoactive intestinal peptide receptor 1
VWF von Willebrand factor
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma