Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the chenodeoxycholic acid-2402 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACVR1B | activin A receptor, type IB |
ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
ANK1 | ankyrin 1, erythrocytic |
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
ARNT | aryl hydrocarbon receptor nuclear translocator |
ARRB2 | arrestin, beta 2 |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
ATG10 | autophagy related 10 |
ATP10B | ATPase, class V, type 10B |
AURKA | aurora kinase A |
BCAS1 | breast carcinoma amplified sequence 1 |
C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CD59 | CD59 molecule, complement regulatory protein |
CDK3 | cyclin-dependent kinase 3 |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CIB2 | calcium and integrin binding family member 2 |
CLUAP1 | clusterin associated protein 1 |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
DLG2 | discs, large homolog 2 (Drosophila) |
DSCAM | Down syndrome cell adhesion molecule |
DSG3 | desmoglein 3 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
EFNA3 | ephrin-A3 |
EXOSC1 | exosome component 1 |
F11R | F11 receptor |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FBXO22 | F-box protein 22 |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FLJ11292 | |
FRMD1 | FERM domain containing 1 |
GEMIN7 | gem (nuclear organelle) associated protein 7 |
GM2A | GM2 ganglioside activator |
GPM6B | glycoprotein M6B |
GRB7 | growth factor receptor-bound protein 7 |
GSTTP1 | glutathione S-transferase theta pseudogene 1 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
ICA1 | islet cell autoantigen 1, 69kDa |
ING2 | inhibitor of growth family, member 2 |
INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
ITM2B | integral membrane protein 2B |
KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KHK | ketohexokinase (fructokinase) |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
LTBP3 | latent transforming growth factor beta binding protein 3 |
MAPK8 | mitogen-activated protein kinase 8 |
MCPH1 | microcephalin 1 |
MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
NBL1 | neuroblastoma 1, DAN family BMP antagonist |
NEBL | nebulette |
NF2 | neurofibromin 2 (merlin) |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
OAZ3 | ornithine decarboxylase antizyme 3 |
OBSL1 | obscurin-like 1 |
PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
PDLIM5 | PDZ and LIM domain 5 |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
PLCL2 | phospholipase C-like 2 |
PLK4 | polo-like kinase 4 |
POLL | polymerase (DNA directed), lambda |
PON1 | paraoxonase 1 |
PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
PTPRA | protein tyrosine phosphatase, receptor type, A |
RANBP3 | RAN binding protein 3 |
RAP1GAP | RAP1 GTPase activating protein |
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
RGS3 | regulator of G-protein signaling 3 |
RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
RTCA | RNA 3'-terminal phosphate cyclase |
RUNX1 | runt-related transcription factor 1 |
SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
SNX13 | sorting nexin 13 |
SPAG8 | sperm associated antigen 8 |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
SS18 | synovial sarcoma translocation, chromosome 18 |
SSBP2 | single-stranded DNA binding protein 2 |
SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
TEX15 | testis expressed 15 |
TM2D1 | TM2 domain containing 1 |
TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
TRBC1 | T cell receptor beta constant 1 |
TROVE2 | TROVE domain family, member 2 |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
WSCD1 | WSC domain containing 1 |
ZNF177 | zinc finger protein 177 |
ZSCAN32 | zinc finger and SCAN domain containing 32 |
Symbol | Name |
---|---|
ACADSB | acyl-CoA dehydrogenase, short/branched chain |
ACP6 | acid phosphatase 6, lysophosphatidic |
ANKRD36 | ankyrin repeat domain 36 |
ANKRD40 | ankyrin repeat domain 40 |
AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
ART1 | ADP-ribosyltransferase 1 |
ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
ATP7B | ATPase, Cu++ transporting, beta polypeptide |
AXIN1 | axin 1 |
C17ORF70 | chromosome 17 open reading frame 70 |
C1ORF95 | chromosome 1 open reading frame 95 |
C6ORF47 | chromosome 6 open reading frame 47 |
C7ORF43 | chromosome 7 open reading frame 43 |
CAPN5 | calpain 5 |
CASZ1 | castor zinc finger 1 |
CBX4 | chromobox homolog 4 |
CCDC71 | coiled-coil domain containing 71 |
CD70 | CD70 molecule |
CDR2L | cerebellar degeneration-related protein 2-like |
CIC | capicua transcriptional repressor |
CIT | citron rho-interacting serine/threonine kinase |
CKB | creatine kinase, brain |
CNPY4 | canopy FGF signaling regulator 4 |
COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
CPTP | ceramide-1-phosphate transfer protein |
CRYL1 | crystallin, lambda 1 |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
DDN | dendrin |
DEAF1 | DEAF1 transcription factor |
DSPP | dentin sialophosphoprotein |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
ELP6 | elongator acetyltransferase complex subunit 6 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
EXD3 | exonuclease 3'-5' domain containing 3 |
FAM188A | family with sequence similarity 188, member A |
FEM1C | fem-1 homolog c (C. elegans) |
FLCN | folliculin |
FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
GLCE | glucuronic acid epimerase |
GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
GSTCD | glutathione S-transferase, C-terminal domain containing |
HDAC5 | histone deacetylase 5 |
KIF3B | kinesin family member 3B |
KLF11 | Kruppel-like factor 11 |
KLK15 | kallikrein-related peptidase 15 |
LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
LINC00597 | long intergenic non-protein coding RNA 597 |
LSP1 | lymphocyte-specific protein 1 |
MOCOS | molybdenum cofactor sulfurase |
MTA2 | metastasis associated 1 family, member 2 |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
NIPAL2 | NIPA-like domain containing 2 |
NKX3-2 | NK3 homeobox 2 |
NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
NXF2 | nuclear RNA export factor 2 |
PARG | poly (ADP-ribose) glycohydrolase |
PCDH12 | protocadherin 12 |
PDZD7 | PDZ domain containing 7 |
PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
PODXL2 | podocalyxin-like 2 |
PRKG2 | protein kinase, cGMP-dependent, type II |
PYCR1 | pyrroline-5-carboxylate reductase 1 |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RNF122 | ring finger protein 122 |
RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
RPAP2 | RNA polymerase II associated protein 2 |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SHARPIN | SHANK-associated RH domain interactor |
SHPK | sedoheptulokinase |
SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
SLC22A14 | solute carrier family 22, member 14 |
SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
SPATA2L | spermatogenesis associated 2-like |
ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
STAG3 | stromal antigen 3 |
TBC1D2 | TBC1 domain family, member 2 |
TBX19 | T-box 19 |
TEC | tec protein tyrosine kinase |
TNRC6B | trinucleotide repeat containing 6B |
TRAF2 | TNF receptor-associated factor 2 |
TRAIP | TRAF interacting protein |
TRIM26 | tripartite motif containing 26 |
TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
TTC23 | tetratricopeptide repeat domain 23 |
TUBA4B | tubulin, alpha 4b |
URM1 | ubiquitin related modifier 1 |
VEGFB | vascular endothelial growth factor B |
VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
WASF3 | WAS protein family, member 3 |
WFDC2 | WAP four-disulfide core domain 2 |
ZNF408 | zinc finger protein 408 |
ZNF668 | zinc finger protein 668 |
ZNF701 | zinc finger protein 701 |