chloride channel activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. (Gene Ontology, GO_0005254)
External Link http://amigo.geneontology.org/amigo/term/GO:0005254
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Genes

77 genes performing the chloride channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ANO1 anoctamin 1, calcium activated chloride channel
ANO10 anoctamin 10
ANO2 anoctamin 2, calcium activated chloride channel
ANO3 anoctamin 3
ANO4 anoctamin 4
ANO5 anoctamin 5
ANO6 anoctamin 6
ANO7 anoctamin 7
ANO8 anoctamin 8
ANO9 anoctamin 9
APOL1 apolipoprotein L, 1
AQP6 aquaporin 6, kidney specific
BEST1 bestrophin 1
BEST2 bestrophin 2
BEST3 bestrophin 3
BEST4 bestrophin 4
BSND barttin CLCNK-type chloride channel accessory beta subunit
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CLCA4 chloride channel accessory 4
CLCC1 chloride channel CLIC-like 1
CLCN1 chloride channel, voltage-sensitive 1
CLCN2 chloride channel, voltage-sensitive 2
CLCN3 chloride channel, voltage-sensitive 3
CLCN4 chloride channel, voltage-sensitive 4
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CLCNKA chloride channel, voltage-sensitive Ka
CLCNKB chloride channel, voltage-sensitive Kb
CLIC1 chloride intracellular channel 1
CLIC2 chloride intracellular channel 2
CLIC3 chloride intracellular channel 3
CLIC4 chloride intracellular channel 4
CLIC6 chloride intracellular channel 6
FXYD1 FXYD domain containing ion transport regulator 1
FXYD3 FXYD domain containing ion transport regulator 3
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GLRA1 glycine receptor, alpha 1
GLRA2 glycine receptor, alpha 2
GLRA3 glycine receptor, alpha 3
GLRB glycine receptor, beta
MFSD8 major facilitator superfamily domain containing 8
NMUR2 neuromedin U receptor 2
OCA2 oculocutaneous albinism II
PACC1 proton activated chloride channel 1
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC26A11 solute carrier family 26 (anion exchanger), member 11
SLC26A7 solute carrier family 26 (anion exchanger), member 7
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC26A9 solute carrier family 26 (anion exchanger), member 9
TMC4 transmembrane channel-like 4
TTYH1 tweety family member 1
TTYH2 tweety family member 2
TTYH3 tweety family member 3