chlorogenic acid-4142 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the chlorogenic acid-4142 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL2 angiopoietin-like 2
AOX1 aldehyde oxidase 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
B9D1 B9 protein domain 1
B9D2 B9 protein domain 2
BCORL1 BCL6 corepressor-like 1
C2ORF27A chromosome 2 open reading frame 27A
C6ORF47 chromosome 6 open reading frame 47
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD47 CD47 molecule
CDC14A cell division cycle 14A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEND1 cell cycle exit and neuronal differentiation 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
DEPDC5 DEP domain containing 5
DFNB31 deafness, autosomal recessive 31
DKFZP434L187 uncharacterized LOC26082
EFNB3 ephrin-B3
EPHB2 EPH receptor B2
FAM171A1 family with sequence similarity 171, member A1
FAM188A family with sequence similarity 188, member A
FAT4 FAT atypical cadherin 4
FBXO21 F-box protein 21
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GGT1 gamma-glutamyltransferase 1
GPR27 G protein-coupled receptor 27
H2AFX H2A histone family, member X
HBEGF heparin-binding EGF-like growth factor
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HPX hemopexin
HSPG2 heparan sulfate proteoglycan 2
ICK intestinal cell (MAK-like) kinase
IGKV1D-13 immunoglobulin kappa variable 1D-13
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA1107 KIAA1107
KMT2A lysine (K)-specific methyltransferase 2A
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTB4R leukotriene B4 receptor
MALL mal, T-cell differentiation protein-like
MEFV Mediterranean fever
MID1 midline 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP25 matrix metallopeptidase 25
MPPE1 metallophosphoesterase 1
MXD4 MAX dimerization protein 4
MYCNOS MYCN opposite strand
MYL10 myosin, light chain 10, regulatory
NEUROD6 neuronal differentiation 6
NF2 neurofibromin 2 (merlin)
NME5 NME/NM23 family member 5
OMG oligodendrocyte myelin glycoprotein
PCDHB3 protocadherin beta 3
PCNX pecanex homolog (Drosophila)
PER3 period circadian clock 3
PLTP phospholipid transfer protein
PLXNB3 plexin B3
POLM polymerase (DNA directed), mu
PRDX2 peroxiredoxin 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RASIP1 Ras interacting protein 1
RIN1 Ras and Rab interactor 1
RNASEH1 ribonuclease H1
RORC RAR-related orphan receptor C
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SH3BP2 SH3-domain binding protein 2
SH3GL3 SH3-domain GRB2-like 3
SLC17A4 solute carrier family 17, member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SNX13 sorting nexin 13
SOX21 SRY (sex determining region Y)-box 21
SPON1 spondin 1, extracellular matrix protein
SRSF5 serine/arginine-rich splicing factor 5
SSPN sarcospan
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBXA2R thromboxane A2 receptor
TRIB2 tribbles pseudokinase 2
TUBA3C tubulin, alpha 3c
UBOX5 U-box domain containing 5
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNT16 wingless-type MMTV integration site family, member 16
ZFHX2 zinc finger homeobox 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTL8 actin-like 8
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AOC2 amine oxidase, copper containing 2 (retina-specific)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF79 chromosome 14 open reading frame 79
C14ORF93 chromosome 14 open reading frame 93
C8ORF60 chromosome 8 open reading frame 60
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCA1 chloride channel accessory 1
CNTNAP1 contactin associated protein 1
CPB2 carboxypeptidase B2 (plasma)
CRMP1 collapsin response mediator protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DBF4B DBF4 zinc finger B
DENND5B DENN/MADD domain containing 5B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EPX eosinophil peroxidase
ERC2-IT1 ERC2 intronic transcript 1
EXOSC1 exosome component 1
FADS2 fatty acid desaturase 2
FFAR2 free fatty acid receptor 2
FGF22 fibroblast growth factor 22
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR22 G protein-coupled receptor 22
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H2BO histone cluster 1, H2bo
HIST1H3E histone cluster 1, H3e
HIST1H4A histone cluster 1, H4a
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HOXB6 homeobox B6
HOXD11 homeobox D11
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IBSP integrin-binding sialoprotein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL11RA interleukin 11 receptor, alpha
IL20RA interleukin 20 receptor, alpha
IQSEC2 IQ motif and Sec7 domain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF13 Kruppel-like factor 13
KRT83 keratin 83, type II
LEFTY1 left-right determination factor 1
LOC100131510 uncharacterized LOC100131510
LOC79999 uncharacterized LOC79999
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC48 leucine rich repeat containing 48
LTBP2 latent transforming growth factor beta binding protein 2
LTC4S leukotriene C4 synthase
MANBA mannosidase, beta A, lysosomal
NELL2 NEL-like 2 (chicken)
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
NNAT neuronatin
OCA2 oculocutaneous albinism II
ONECUT2 one cut homeobox 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIPOX pipecolic acid oxidase
PRDM14 PR domain containing 14
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTPRM protein tyrosine phosphatase, receptor type, M
PXDC1 PX domain containing 1
PYHIN1 pyrin and HIN domain family, member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RNF122 ring finger protein 122
RPA4 replication protein A4, 30kDa
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC3 syndecan 3
SIPA1 signal-induced proliferation-associated 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SNTA1 syntrophin, alpha 1
STEAP4 STEAP family member 4
TAGLN3 transgelin 3
TBX19 T-box 19
TNS2 tensin 2
VIM vimentin
VPS9D1 VPS9 domain containing 1
XDH xanthine dehydrogenase
ZBTB44 zinc finger and BTB domain containing 44
ZMAT4 zinc finger, matrin-type 4