chlorothiazide Gene Set
Genes
25 genes differentially expressed following the chlorothiazide small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EED
|
embryonic ectoderm development
|
4.02432
|
|
ALPI
|
alkaline phosphatase, intestinal
|
3.9118
|
|
KLHDC2
|
kelch domain containing 2
|
3.78718
|
|
MORN1
|
MORN repeat containing 1
|
3.6498
|
|
AXIN1
|
axin 1
|
3.63771
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
3.60053
|
|
DYNC2H1
|
dynein, cytoplasmic 2, heavy chain 1
|
3.58766
|
|
GP1BB
|
glycoprotein Ib (platelet), beta polypeptide
|
3.55972
|
|
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
|
3.33646
|
|
ELAVL3
|
ELAV like neuron-specific RNA binding protein 3
|
3.21374
|
|
MLXIPL
|
MLX interacting protein-like
|
3.20158
|
|
CHRNB3
|
cholinergic receptor, nicotinic, beta 3 (neuronal)
|
3.19421
|
|
VRTN
|
vertebrae development associated
|
3.18618
|
|
ZNF205
|
zinc finger protein 205
|
3.09722
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
3.08899
|
|
ITPK1
|
inositol-tetrakisphosphate 1-kinase
|
3.0246
|
|
CYP2A13
|
cytochrome P450, family 2, subfamily A, polypeptide 13
|
3.02032
|
|
ZNF646
|
zinc finger protein 646
|
3.02018
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-4.71136
|
|
DFFB
|
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
|
-4.28549
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
-4.2501
|
|
CSRP1
|
cysteine and glycine-rich protein 1
|
-3.81007
|
|
CDC25B
|
cell division cycle 25B
|
-3.18741
|
|
THBD
|
thrombomodulin
|
-3.10568
|
|
JMJD7
|
jumonji domain containing 7
|
-3.00165
|
