| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the chlorzoxazone-7456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM2 | absent in melanoma 2 |
| ALPK1 | alpha-kinase 1 |
| APC | adenomatous polyposis coli |
| AQP3 | aquaporin 3 (Gill blood group) |
| AURKA | aurora kinase A |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CD22 | CD22 molecule |
| CPNE7 | copine VII |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DMC1 | DNA meiotic recombinase 1 |
| DRD2 | dopamine receptor D2 |
| DST | dystonin |
| FLCN | folliculin |
| FLOT1 | flotillin 1 |
| FOXN3 | forkhead box N3 |
| FZD9 | frizzled class receptor 9 |
| GM2A | GM2 ganglioside activator |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GYG2 | glycogenin 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAND2-AS1 | HAND2 antisense RNA 1 (head to head) |
| HBP1 | HMG-box transcription factor 1 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HHAT | hedgehog acyltransferase |
| HOXD1 | homeobox D1 |
| IFNA17 | interferon, alpha 17 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| INHBC | inhibin, beta C |
| ISL1 | ISL LIM homeobox 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JRK | Jrk homolog (mouse) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KRT8 | keratin 8, type II |
| LMAN1 | lectin, mannose-binding, 1 |
| LPIN1 | lipin 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MED31 | mediator complex subunit 31 |
| MOB3B | MOB kinase activator 3B |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| NF2 | neurofibromin 2 (merlin) |
| NKX2-1 | NK2 homeobox 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUDCD3 | NudC domain containing 3 |
| NYX | nyctalopin |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLXNB1 | plexin B1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRDM12 | PR domain containing 12 |
| PRDM9 | PR domain containing 9 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PVR | poliovirus receptor |
| PXDC1 | PX domain containing 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RECQL5 | RecQ protein-like 5 |
| RGS12 | regulator of G-protein signaling 12 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPL7 | ribosomal protein L7 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RREB1 | ras responsive element binding protein 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| S100A8 | S100 calcium binding protein A8 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SIX2 | SIX homeobox 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC26A10 | solute carrier family 26, member 10 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| ST20 | suppressor of tumorigenicity 20 |
| STAB2 | stabilin 2 |
| STAT5B | signal transducer and activator of transcription 5B |
| TBC1D5 | TBC1 domain family, member 5 |
| TBX5 | T-box 5 |
| TEK | TEK tyrosine kinase, endothelial |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TIMELESS | timeless circadian clock |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| WDR25 | WD repeat domain 25 |
| ZNF235 | zinc finger protein 235 |
| ZNF747 | zinc finger protein 747 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAGE | B melanoma antigen |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRD9 | bromodomain containing 9 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CASD1 | CAS1 domain containing 1 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CCS | copper chaperone for superoxide dismutase |
| CENPJ | centromere protein J |
| CHML | choroideremia-like (Rab escort protein 2) |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTSV | cathepsin V |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNM1 | dynamin 1 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EIF2B5 | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa |
| ESRRA | estrogen-related receptor alpha |
| FA2H | fatty acid 2-hydroxylase |
| FAM222B | family with sequence similarity 222, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FZD2 | frizzled class receptor 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLMN | glomulin, FKBP associated protein |
| GPATCH2 | G patch domain containing 2 |
| GPR87 | G protein-coupled receptor 87 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HHLA3 | HERV-H LTR-associating 3 |
| HINFP | histone H4 transcription factor |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMOX1 | heme oxygenase 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF2 | interferon regulatory factor 2 |
| KIFAP3 | kinesin-associated protein 3 |
| KLHL26 | kelch-like family member 26 |
| KLHL36 | kelch-like family member 36 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| METTL2B | methyltransferase like 2B |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NHLRC2 | NHL repeat containing 2 |
| NMRK1 | nicotinamide riboside kinase 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RLN2 | relaxin 2 |
| RNF25 | ring finger protein 25 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SALL2 | spalt-like transcription factor 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SH2B3 | SH2B adaptor protein 3 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SSFA2 | sperm specific antigen 2 |
| STBD1 | starch binding domain 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM127 | transmembrane protein 127 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TRIM25 | tripartite motif containing 25 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UBXN6 | UBX domain protein 6 |
| UFSP2 | UFM1-specific peptidase 2 |
| ULBP2 | UL16 binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| XPA | xeroderma pigmentosum, complementation group A |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF33B | zinc finger protein 33B |
| ZNF443 | zinc finger protein 443 |
| ZNF8 | zinc finger protein 8 |
