cholangiocarcinoma Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

258 genes co-occuring with the biological term cholangiocarcinoma in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADIPOR1 adiponectin receptor 1
AFP alpha-fetoprotein
AGR3 anterior gradient 3
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT2 angiopoietin 2
ANXA1 annexin A1
ANXA2 annexin A2
AQP1 aquaporin 1 (Colton blood group)
ARG1 arginase 1
ASMT acetylserotonin O-methyltransferase
ASPH aspartate beta-hydroxylase
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAPG capping protein (actin filament), gelsolin-like
CAPNS1 calpain, small subunit 1
CCND1 cyclin D1
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CD151 CD151 molecule (Raph blood group)
CD24 CD24 molecule
CD274 CD274 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHRM3 cholinergic receptor, muscarinic 3
CKAP4 cytoskeleton-associated protein 4
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CREB1 cAMP responsive element binding protein 1
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAPK1 death-associated protein kinase 1
DCN decorin
DMAP1 DNA methyltransferase 1 associated protein 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP1 dual specificity phosphatase 1
ECM1 extracellular matrix protein 1
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASLG Fas ligand (TNF superfamily, member 6)
FGFR2 fibroblast growth factor receptor 2
FHIT fragile histidine triad
FLT1 fms-related tyrosine kinase 1
FOXC2 forkhead box C2
FSCN1 fascin actin-bundling protein 1
GAB1 GRB2-associated binding protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GATA6 GATA binding protein 6
GLI1 GLI family zinc finger 1
GLP1R glucagon-like peptide 1 receptor
GNAS GNAS complex locus
GNMT glycine N-methyltransferase
GOPC golgi-associated PDZ and coiled-coil motif containing
GRN granulin
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HDAC6 histone deacetylase 6
HDC histidine decarboxylase
HDGF hepatoma-derived growth factor
HMGA2 high mobility group AT-hook 2
HOMER1 homer scaffolding protein 1
HPSE heparanase
HRH3 histamine receptor H3
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL6 interleukin 6
IL6R interleukin 6 receptor
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
L1CAM L1 cell adhesion molecule
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LEF1 lymphoid enhancer-binding factor 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAOA monoamine oxidase A
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MARCKS myristoylated alanine-rich protein kinase C substrate
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MICA MHC class I polypeptide-related sequence A
MIR101-1 microRNA 101-1
MIR146A microRNA 146a
MIR200C microRNA 200c
MIR204 microRNA 204
MIR205 microRNA 205
MIR21 microRNA 21
MIR214 microRNA 214
MIR221 microRNA 221
MIR25 microRNA 25
MIR29B1 microRNA 29b-1
MIR373 microRNA 373
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MST1 macrophage stimulating 1
MSX2 msh homeobox 2
MTA1 metastasis associated 1
MTF1 metal-regulatory transcription factor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCOA3 nuclear receptor coactivator 3
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NOTCH1 notch 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
OSBP2 oxysterol binding protein 2
OSBPL7 oxysterol binding protein-like 7
PAWR PRKC, apoptosis, WT1, regulator
PBK PDZ binding kinase
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFD platelet derived growth factor D
PGF placental growth factor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLK2 polo-like kinase 2
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDM2 PR domain containing 2, with ZNF domain
PRDX1 peroxiredoxin 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCI protein kinase C, iota
PROM1 prominin 1
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK7 protein tyrosine kinase 7 (inactive)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PYCARD PYD and CARD domain containing
RAD51AP1 RAD51 associated protein 1
RARG retinoic acid receptor, gamma
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RHOC ras homolog family member C
RNU2-1 RNA, U2 small nuclear 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPSA ribosomal protein SA
RRM1 ribonucleotide reductase M1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
S1PR2 sphingosine-1-phosphate receptor 2
SAFB scaffold attachment factor B
SALL4 spalt-like transcription factor 4
SCTR secretin receptor
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SHH sonic hedgehog
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD7 SMAD family member 7
SMYD3 SET and MYND domain containing 3
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SPATA20 spermatogenesis associated 20
SPP1 secreted phosphoprotein 1
SRRT serrate, RNA effector molecule
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TTR transthyretin
TYMP thymidine phosphorylase
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
WISP1 WNT1 inducible signaling pathway protein 1
WTAP Wilms tumor 1 associated protein
WWOX WW domain containing oxidoreductase