cholangitis Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A bile duct disease that is an inflammation of the bile duct. (Human Disease Ontology, DOID_9446)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:9446
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Genes

61 genes associated with the disease cholangitis in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
MST1 macrophage stimulating 1 1.8787
GPR35 G protein-coupled receptor 35 1.48714
TCF4 transcription factor 4 1.37327
GAS7 growth arrest-specific 7 1.20583
IL2RA interleukin 2 receptor, alpha 1.20583
HDAC7 histone deacetylase 7 1.19386
PLXNA4 plexin A4 1.17101
PTPRU protein tyrosine phosphatase, receptor type, U 1.16174
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 1.14065
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 1.12892
BSPRY B-box and SPRY domain containing 1.11813
KIRREL3 kin of IRRE like 3 (Drosophila) 1.08866
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.971169
TENM4 teneurin transmembrane protein 4 0.905653
STK35 serine/threonine kinase 35 0.78442
ACAD9 acyl-CoA dehydrogenase family, member 9 0.753174
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.679107
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.659337
AJAP1 adherens junctions associated protein 1 0.659337
MTUS2 microtubule associated tumor suppressor candidate 2 0.644215
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.634147
ZPR1 ZPR1 zinc finger 0.629714
GLDC glycine dehydrogenase (decarboxylating) 0.625701
LY9 lymphocyte antigen 9 0.621951
THSD7A thrombospondin, type I, domain containing 7A 0.618434
KDM4C lysine (K)-specific demethylase 4C 0.611686
PEX14 peroxisomal biogenesis factor 14 0.611686
TSC1 tuberous sclerosis 1 0.611686
KLHL29 kelch-like family member 29 0.608439
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 0.605359
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.59964
AGBL4 ATP/GTP binding protein-like 4 0.59964
CNTN4 contactin 4 0.596808
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 0.596808
GPC6 glypican 6 0.594024
LYZL2 lysozyme-like 2 0.594024
ONECUT1 one cut homeobox 1 0.588801
AK8 adenylate kinase 8 0.588801
GRID1 glutamate receptor, ionotropic, delta 1 0.583982
ASTN2 astrotactin 2 0.574821
TTBK1 tau tubulin kinase 1 0.570595
CEP85 centrosomal protein 85kDa 0.568581
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.560918
SDCCAG8 serologically defined colon cancer antigen 8 0.552035
LMX1B LIM homeobox transcription factor 1, beta 0.550393
LIPK lipase, family member K 0.54879
ELL elongation factor RNA polymerase II 0.547225
CRTAC1 cartilage acidic protein 1 0.539566
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.538104
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.535269
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.532547
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.527413
CSMD1 CUB and Sushi multiple domains 1 0.527413
LPPR1 lipid phosphate phosphatase-related protein type 1 0.520364
FBXL13 F-box and leucine-rich repeat protein 13 0.512985
HIP1 huntingtin interacting protein 1 0.511996
FGF14 fibroblast growth factor 14 0.511021
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.508182
CSMD2 CUB and Sushi multiple domains 2 0.506603
ADAM17 ADAM metallopeptidase domain 17 0.505194
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 0.501181