cholesterol biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. (Gene Ontology, GO_0006695)
External Link http://amigo.geneontology.org/amigo/term/GO:0006695
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Genes

26 genes participating in the cholesterol biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACLY ATP citrate lyase
ARV1 ARV1 homolog (S. cerevisiae)
CES1 carboxylesterase 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
LBR lamin B receptor
LMBR1 limb development membrane protein 1
MSMO1 methylsterol monooxygenase 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NPC1L1 NPC1-like 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PLPP6 phospholipid phosphatase 6
PMVK phosphomevalonate kinase
SC5D sterol-C5-desaturase
SH3D19 SH3 domain containing 19
TM7SF2 transmembrane 7 superfamily member 2
UBL4A ubiquitin-like 4A