chromosomal breakage induced by crosslinking agents Gene Set

Dataset	HPO Gene-Disease Associations
Category	disease or phenotype associations
Type	phenotype
Description	Increased amount of chromosomal breaks in cultured blood lymphocytes or other cells induced by treatment with DNA cross-linking agents such as diepoxybutane and mitomycin C. (Human Phenotype Ontology, HP_0003221)
External Link	http://compbio.charite.de/hpoweb/showterm?id=HP:0003221
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Genes

8 genes associated with the chromosomal breakage induced by crosslinking agents phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol	Name
BRCA2	breast cancer 2, early onset
BRIP1	BRCA1 interacting protein C-terminal helicase 1
FANCA	Fanconi anemia, complementation group A
FANCC	Fanconi anemia, complementation group C
FANCD2	Fanconi anemia, complementation group D2
FANCE	Fanconi anemia, complementation group E
FANCI	Fanconi anemia, complementation group I
PALB2	partner and localizer of BRCA2