chrysin-3106 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the chrysin-3106 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACSM1 acyl-CoA synthetase medium-chain family member 1
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ANKRD46 ankyrin repeat domain 46
APOLD1 apolipoprotein L domain containing 1
AVIL advillin
BMP7 bone morphogenetic protein 7
BTBD18 BTB (POZ) domain containing 18
BTF3P11 basic transcription factor 3 pseudogene 11
CA5B carbonic anhydrase VB, mitochondrial
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CBX5 chromobox homolog 5
CCDC144A coiled-coil domain containing 144A
CCL21 chemokine (C-C motif) ligand 21
CELP carboxyl ester lipase pseudogene
CLEC4A C-type lectin domain family 4, member A
COL10A1 collagen, type X, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CUX1 cut-like homeobox 1
CXCL6 chemokine (C-X-C motif) ligand 6
CYHR1 cysteine/histidine-rich 1
DENND1A DENN/MADD domain containing 1A
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GPR15 G protein-coupled receptor 15
GPR22 G protein-coupled receptor 22
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HBS1L HBS1-like translational GTPase
HCG4 HLA complex group 4 (non-protein coding)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRF4 interferon regulatory factor 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KRT9 keratin 9, type I
LCMT2 leucine carboxyl methyltransferase 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIME1 Lck interacting transmembrane adaptor 1
LOC157562 uncharacterized LOC157562
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC75B leucine rich repeat containing 75B
LRRN3 leucine rich repeat neuronal 3
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MID1 midline 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP1 matrix metallopeptidase 1
MPDZ multiple PDZ domain protein
MSH4 mutS homolog 4
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTL5 metallothionein-like 5, testis-specific (tesmin)
N4BP2L2 NEDD4 binding protein 2-like 2
NEB nebulin
NPR3 natriuretic peptide receptor 3
NT5E 5'-nucleotidase, ecto (CD73)
NUP88 nucleoporin 88kDa
OMG oligodendrocyte myelin glycoprotein
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR6 progestin and adipoQ receptor family member VI
PDGFA platelet-derived growth factor alpha polypeptide
PDZK1 PDZ domain containing 1
PEX26 peroxisomal biogenesis factor 26
PLA2G3 phospholipase A2, group III
POPDC2 popeye domain containing 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDM2 PR domain containing 2, with ZNF domain
RGS5 regulator of G-protein signaling 5
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RTCA RNA 3'-terminal phosphate cyclase
SCG5 secretogranin V
SF3B3 splicing factor 3b, subunit 3, 130kDa
SH2B1 SH2B adaptor protein 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SNPH syntaphilin
SOCS2 suppressor of cytokine signaling 2
SORBS3 sorbin and SH3 domain containing 3
SRR serine racemase
SSTR5 somatostatin receptor 5
ST20 suppressor of tumorigenicity 20
STAC SH3 and cysteine rich domain
SYCP2 synaptonemal complex protein 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAS2R10 taste receptor, type 2, member 10
TEF thyrotrophic embryonic factor
TGM4 transglutaminase 4
THAP10 THAP domain containing 10
TMEM51 transmembrane protein 51
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPH1 tryptophan hydroxylase 1
TXK TXK tyrosine kinase
UCN urocortin
ZNF137P zinc finger protein 137, pseudogene
ZNF154 zinc finger protein 154
ZNF276 zinc finger protein 276

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABHD11 abhydrolase domain containing 11
ABHD3 abhydrolase domain containing 3
ACPP acid phosphatase, prostate
ADAP2 ArfGAP with dual PH domains 2
ADORA3 adenosine A3 receptor
AGBL5 ATP/GTP binding protein-like 5
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ANKRD55 ankyrin repeat domain 55
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARRB1 arrestin, beta 1
ATP10D ATPase, class V, type 10D
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
AVEN apoptosis, caspase activation inhibitor
BAMBI BMP and activin membrane-bound inhibitor
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCR2 chemokine (C-C motif) receptor 2
CD244 CD244 molecule, natural killer cell receptor 2B4
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYSLTR1 cysteinyl leukotriene receptor 1
DCPS decapping enzyme, scavenger
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DENND2D DENN/MADD domain containing 2D
ELP6 elongator acetyltransferase complex subunit 6
ENAH enabled homolog (Drosophila)
EPHA4 EPH receptor A4
EPS8 epidermal growth factor receptor pathway substrate 8
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FKBP5 FK506 binding protein 5
GCH1 GTP cyclohydrolase 1
GPHN gephyrin
GSTM2 glutathione S-transferase mu 2 (muscle)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDAC9 histone deacetylase 9
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2BC histone cluster 1, H2bc
HSPA4L heat shock 70kDa protein 4-like
IFI6 interferon, alpha-inducible protein 6
IL24 interleukin 24
IRF8 interferon regulatory factor 8
JADE3 jade family PHD finger 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
L2HGDH L-2-hydroxyglutarate dehydrogenase
LPAR6 lysophosphatidic acid receptor 6
LXN latexin
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MCRS1 microspherule protein 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSRB1 methionine sulfoxide reductase B1
MX2 MX dynamin-like GTPase 2
MYO1E myosin IE
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2 nuclear factor, erythroid 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUPR1 nuclear protein, transcriptional regulator, 1
OCEL1 occludin/ELL domain containing 1
PARN poly(A)-specific ribonuclease
PCYOX1 prenylcysteine oxidase 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PHTF1 putative homeodomain transcription factor 1
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
POMT1 protein-O-mannosyltransferase 1
PROS1 protein S (alpha)
PWAR5 Prader Willi/Angelman region RNA 5
RECQL4 RecQ protein-like 4
RNF126P1 ring finger protein 126 pseudogene 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPC25 SPC25, NDC80 kinetochore complex component
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STX17 syntaxin 17
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBXAS1 thromboxane A synthase 1 (platelet)
TFEC transcription factor EC
TMEM62 transmembrane protein 62
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSPAN32 tetraspanin 32
USP18 ubiquitin specific peptidase 18
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR33 WD repeat domain 33
ZC4H2 zinc finger, C4H2 domain containing
ZNF10 zinc finger protein 10
ZNF747 zinc finger protein 747