chrysin-5505 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the chrysin-5505 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD6 abhydrolase domain containing 6
ACRV1 acrosomal vesicle protein 1
ACTN2 actinin, alpha 2
AKAP7 A kinase (PRKA) anchor protein 7
APOLD1 apolipoprotein L domain containing 1
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BMP3 bone morphogenetic protein 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CDY1 chromodomain protein, Y-linked, 1
CEMP1 cementum protein 1
CLCA1 chloride channel accessory 1
COL14A1 collagen, type XIV, alpha 1
COPE coatomer protein complex, subunit epsilon
CXCL8 chemokine (C-X-C motif) ligand 8
DFNA5 deafness, autosomal dominant 5
DRD2 dopamine receptor D2
DST dystonin
EML2 echinoderm microtubule associated protein like 2
EMP1 epithelial membrane protein 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FGB fibrinogen beta chain
FST follistatin
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM2 glutamate receptor, metabotropic 2
GSK3A glycogen synthase kinase 3 alpha
HBS1L HBS1-like translational GTPase
HIPK2 homeodomain interacting protein kinase 2
HIST1H3A histone cluster 1, H3a
HLA-G major histocompatibility complex, class I, G
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFT38 intraflagellar transport 38
IL11 interleukin 11
INA internexin neuronal intermediate filament protein, alpha
ITM2C integral membrane protein 2C
KCNIP2 Kv channel interacting protein 2
KLK13 kallikrein-related peptidase 13
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LDB3 LIM domain binding 3
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPL lipoprotein lipase
LRRC61 leucine rich repeat containing 61
LRRN3 leucine rich repeat neuronal 3
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAP2 microtubule-associated protein 2
MAPK10 mitogen-activated protein kinase 10
MET MET proto-oncogene, receptor tyrosine kinase
MID1 midline 1
MTRF1L mitochondrial translational release factor 1-like
MTSS1L metastasis suppressor 1-like
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEK11 NIMA-related kinase 11
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRN1 neuritin 1
PAQR6 progestin and adipoQ receptor family member VI
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM5 PDZ and LIM domain 5
PDZD2 PDZ domain containing 2
PON1 paraoxonase 1
PRND prion protein 2 (dublet)
PRSS50 protease, serine, 50
PTGDS prostaglandin D2 synthase 21kDa (brain)
PXDC1 PX domain containing 1
RNF186 ring finger protein 186
RPH3A rabphilin 3A
S100A8 S100 calcium binding protein A8
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC43A3 solute carrier family 43, member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPN sialophorin
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX3 synovial sarcoma, X breakpoint 3
TAT tyrosine aminotransferase
TBC1D22A TBC1 domain family, member 22A
TLE2 transducin-like enhancer of split 2
TMEM63A transmembrane protein 63A
TMPRSS2 transmembrane protease, serine 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSHZ2 teashirt zinc finger homeobox 2
WIF1 WNT inhibitory factor 1
WSCD1 WSC domain containing 1
ZNF287 zinc finger protein 287
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ADRA2C adrenoceptor alpha 2C
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARL15 ADP-ribosylation factor-like 15
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATG4A autophagy related 4A, cysteine peptidase
BCL7B B-cell CLL/lymphoma 7B
BIK BCL2-interacting killer (apoptosis-inducing)
BTF3P12 basic transcription factor 3 pseudogene 12
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C5 complement component 5
C9ORF40 chromosome 9 open reading frame 40
CASP3 caspase 3, apoptosis-related cysteine peptidase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP72 centrosomal protein 72kDa
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLASP1 cytoplasmic linker associated protein 1
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO2A coronin, actin binding protein, 2A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY1 cryptochrome circadian clock 1
CUTC cutC copper transporter
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DHRS3 dehydrogenase/reductase (SDR family) member 3
FAM53B family with sequence similarity 53, member B
FGD6 FYVE, RhoGEF and PH domain containing 6
FLCN folliculin
FLRT3 fibronectin leucine rich transmembrane protein 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPRC5C G protein-coupled receptor, class C, group 5, member C
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
HIST1H3G histone cluster 1, H3g
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
IRX4 iroquois homeobox 4
KAT2B K(lysine) acetyltransferase 2B
KIFAP3 kinesin-associated protein 3
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
MARC1 mitochondrial amidoxime reducing component 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MFSD11 major facilitator superfamily domain containing 11
MMP9 matrix metallopeptidase 9
MPDU1 mannose-P-dolichol utilization defect 1
NAGK N-acetylglucosamine kinase
NKAIN1 Na+/K+ transporting ATPase interacting 1
ORC2 origin recognition complex, subunit 2
PALB2 partner and localizer of BRCA2
PHACTR4 phosphatase and actin regulator 4
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMM1 phosphomannomutase 1
PRPH peripherin
PYCRL pyrroline-5-carboxylate reductase-like
RAB23 RAB23, member RAS oncogene family
RASA2 RAS p21 protein activator 2
REEP4 receptor accessory protein 4
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCHIP1 schwannomin interacting protein 1
SETMAR SET domain and mariner transposase fusion gene
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIRAL2 SIR2 antiphage like 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPAG1 sperm associated antigen 1
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
TM6SF1 transmembrane 6 superfamily member 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM5 tripartite motif containing 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC17 tetratricopeptide repeat domain 17
VCPKMT valosin containing protein lysine (K) methyltransferase
WDR18 WD repeat domain 18
WDR19 WD repeat domain 19
YPEL5 yippee-like 5 (Drosophila)
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF189 zinc finger protein 189
ZNF212 zinc finger protein 212
ZNF226 zinc finger protein 226
ZNF273 zinc finger protein 273
ZNF329 zinc finger protein 329
ZNF573 zinc finger protein 573
ZNF696 zinc finger protein 696
ZNF83 zinc finger protein 83