chrysin-6485 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the chrysin-6485 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTN2 actinin, alpha 2
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
B3GAT1 beta-1,3-glucuronyltransferase 1
BMP1 bone morphogenetic protein 1
C16ORF58 chromosome 16 open reading frame 58
CALB2 calbindin 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CATSPERB catsper channel auxiliary subunit beta
CCRL2 chemokine (C-C motif) receptor-like 2
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC2 chloride intracellular channel 2
COL6A1 collagen, type VI, alpha 1
CUZD1 CUB and zona pellucida-like domains 1
CXCR6 chemokine (C-X-C motif) receptor 6
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DLG5 discs, large homolog 5 (Drosophila)
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EGR1 early growth response 1
EGR3 early growth response 3
EML2 echinoderm microtubule associated protein like 2
EXOC7 exocyst complex component 7
FAIM2 Fas apoptotic inhibitory molecule 2
FAM149A family with sequence similarity 149, member A
FBLN1 fibulin 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF17 fibroblast growth factor 17
FGF6 fibroblast growth factor 6
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOSL1 FOS-like antigen 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXYD2 FXYD domain containing ion transport regulator 2
FZD10 frizzled class receptor 10
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLI2 GLI family zinc finger 2
GLS glutaminase
GMPR guanosine monophosphate reductase
GRK5 G protein-coupled receptor kinase 5
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HOXD9 homeobox D9
HP1BP3 heterochromatin protein 1, binding protein 3
IFNB1 interferon, beta 1, fibroblast
IGHMBP2 immunoglobulin mu binding protein 2
INHBC inhibin, beta C
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCTD13 potassium channel tetramerization domain containing 13
KRT75 keratin 75, type II
LAT2 linker for activation of T cells family, member 2
LIF leukemia inhibitory factor
LOC157562 uncharacterized LOC157562
LTC4S leukotriene C4 synthase
MGAM maltase-glucoamylase
MST1 macrophage stimulating 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYLK myosin light chain kinase
N4BP2L2 NEDD4 binding protein 2-like 2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NGDN neuroguidin, EIF4E binding protein
NHLH2 nescient helix loop helix 2
NIPAL3 NIPA-like domain containing 3
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSMR oncostatin M receptor
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLK3 polo-like kinase 3
PRELP proline/arginine-rich end leucine-rich repeat protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVT1 Pvt1 oncogene (non-protein coding)
RCE1 Ras converting CAAX endopeptidase 1
RFPL1 ret finger protein-like 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
S100A8 S100 calcium binding protein A8
SC5D sterol-C5-desaturase
SESN1 sestrin 1
SFTPD surfactant protein D
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMIM7 small integral membrane protein 7
SNED1 sushi, nidogen and EGF-like domains 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STS steroid sulfatase (microsomal), isozyme S
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TM4SF1 transmembrane 4 L six family member 1
TRBC1 T cell receptor beta constant 1
TSSK2 testis-specific serine kinase 2
UCN urocortin
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCAN versican
ZNF276 zinc finger protein 276
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADORA2B adenosine A2b receptor
AKAP12 A kinase (PRKA) anchor protein 12
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX5 armadillo repeat containing, X-linked 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEX4 brain expressed, X-linked 4
BIK BCL2-interacting killer (apoptosis-inducing)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C12ORF4 chromosome 12 open reading frame 4
C1ORF112 chromosome 1 open reading frame 112
CAMTA1 calmodulin binding transcription activator 1
CCDC15 coiled-coil domain containing 15
CCDC28A coiled-coil domain containing 28A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP131 centrosomal protein 131kDa
CLCN5 chloride channel, voltage-sensitive 5
CLDN9 claudin 9
CLDND1 claudin domain containing 1
CRBN cereblon
CXORF56 chromosome X open reading frame 56
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNA2 DNA replication helicase/nuclease 2
DNAL4 dynein, axonemal, light chain 4
DTWD1 DTW domain containing 1
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EXOC2 exocyst complex component 2
FA2H fatty acid 2-hydroxylase
FAIM Fas apoptotic inhibitory molecule
FAM169A family with sequence similarity 169, member A
GTPBP8 GTP-binding protein 8 (putative)
HCFC2 host cell factor C2
HSPA2 heat shock 70kDa protein 2
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFRD1 interferon-related developmental regulator 1
IL4R interleukin 4 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIF11 kinesin family member 11
KIF20B kinesin family member 20B
LIN7B lin-7 homolog B (C. elegans)
LOC100287590 uncharacterized LOC100287590
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTFL1 leucine zipper transcription factor-like 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MEPCE methylphosphate capping enzyme
MRPL41 mitochondrial ribosomal protein L41
MSX1 msh homeobox 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NAGK N-acetylglucosamine kinase
NCSTN nicastrin
NDRG1 N-myc downstream regulated 1
NFE2L3 nuclear factor, erythroid 2-like 3
NPFFR1 neuropeptide FF receptor 1
NUP155 nucleoporin 155kDa
OLFML2A olfactomedin-like 2A
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAQR3 progestin and adipoQ receptor family member III
PARP16 poly (ADP-ribose) polymerase family, member 16
PDZRN3 PDZ domain containing ring finger 3
PECR peroxisomal trans-2-enoyl-CoA reductase
PITX2 paired-like homeodomain 2
PLA2G15 phospholipase A2, group XV
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMP22 peripheral myelin protein 22
RBL1 retinoblastoma-like 1
RGS2 regulator of G-protein signaling 2
RINT1 RAD50 interactor 1
RNF170 ring finger protein 170
RPGR retinitis pigmentosa GTPase regulator
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2D4A SH2 domain containing 4A
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC38A6 solute carrier family 38, member 6
SLC46A3 solute carrier family 46, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOAT1 sterol O-acyltransferase 1
SPC25 SPC25, NDC80 kinetochore complex component
SPHK1 sphingosine kinase 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TMC7 transmembrane channel-like 7
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMT61B tRNA methyltransferase 61B
ZC2HC1A zinc finger, C2HC-type containing 1A
ZIC1 Zic family member 1
ZNF571 zinc finger protein 571
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586