ciclacillin-3800 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ciclacillin-3800 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACE2 angiotensin I converting enzyme 2
AFF2 AF4/FMR2 family, member 2
AQP9 aquaporin 9
B3GAT1 beta-1,3-glucuronyltransferase 1
BMP8B bone morphogenetic protein 8b
BST1 bone marrow stromal cell antigen 1
BTN3A2 butyrophilin, subfamily 3, member A2
C22ORF46 chromosome 22 open reading frame 46
CA9 carbonic anhydrase IX
CALCR calcitonin receptor
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLCA2 chloride channel accessory 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNTD2 cyclin N-terminal domain containing 2
COL11A2 collagen, type XI, alpha 2
CPA2 carboxypeptidase A2 (pancreatic)
CPN2 carboxypeptidase N, polypeptide 2
CSNK1G1 casein kinase 1, gamma 1
CT55 cancer/testis antigen 55
DCAKD dephospho-CoA kinase domain containing
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMPK dystrophia myotonica-protein kinase
DOCK6 dedicator of cytokinesis 6
FAM65B family with sequence similarity 65, member B
FOLR2 folate receptor 2 (fetal)
FRZB frizzled-related protein
GALR3 galanin receptor 3
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GFER growth factor, augmenter of liver regeneration
GFI1 growth factor independent 1 transcription repressor
GOLGA6A golgin A6 family, member A
GRM8 glutamate receptor, metabotropic 8
GZMK granzyme K (granzyme 3; tryptase II)
HLF hepatic leukemia factor
HRG histidine-rich glycoprotein
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INTS1 integrator complex subunit 1
IRAK3 interleukin-1 receptor-associated kinase 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1024 KIAA1024
KLHL18 kelch-like family member 18
KREMEN2 kringle containing transmembrane protein 2
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAG3 lymphocyte-activation gene 3
LARP7 La ribonucleoprotein domain family, member 7
LAT2 linker for activation of T cells family, member 2
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LTB4R leukotriene B4 receptor
MEG3 maternally expressed 3 (non-protein coding)
MIA2 melanoma inhibitory activity 2
MLANA melan-A
MNMIP1 manchette microtubule inner protein 1
MUC8 mucin 8
MYO15A myosin XVA
NRCAM neuronal cell adhesion molecule
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OCM2 oncomodulin 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PCDHA3 protocadherin alpha 3
PDIA2 protein disulfide isomerase family A, member 2
PDPN podoplanin
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PML promyelocytic leukemia
POU5F1P3 POU class 5 homeobox 1 pseudogene 3
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRTN3 proteinase 3
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGIS prostaglandin I2 (prostacyclin) synthase
RBBP4 retinoblastoma binding protein 4
RGS9 regulator of G-protein signaling 9
RNF126P1 ring finger protein 126 pseudogene 1
RUNX1 runt-related transcription factor 1
SCRT1 scratch family zinc finger 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STAB1 stabilin 1
SULF1 sulfatase 1
SYNDIG1 synapse differentiation inducing 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
THTPA thiamine triphosphatase
TMEM176A transmembrane protein 176A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAPPC9 trafficking protein particle complex 9
TRIM15 tripartite motif containing 15
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSPAN8 tetraspanin 8
USP2 ubiquitin specific peptidase 2
VWA5A von Willebrand factor A domain containing 5A
WIF1 WNT inhibitory factor 1
ZMAT4 zinc finger, matrin-type 4

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAP2 ArfGAP with dual PH domains 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P1 annexin A2 pseudogene 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BAHD1 bromo adjacent homology domain containing 1
BBC3 BCL2 binding component 3
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C3 complement component 3
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCNJL cyclin J-like
CCNO cyclin O
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLSTN3 calsyntenin 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CXCL3 chemokine (C-X-C motif) ligand 3
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNM3 dynamin 3
DOK5 docking protein 5
DSPP dentin sialophosphoprotein
EGFL7 EGF-like-domain, multiple 7
ELOVL4 ELOVL fatty acid elongase 4
ETNK2 ethanolamine kinase 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ21369 uncharacterized protein FLJ21369
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLB1L galactosidase, beta 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HHAT hedgehog acyltransferase
HOXA6 homeobox A6
HOXA7 homeobox A7
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCTD17 potassium channel tetramerization domain containing 17
KIAA0754 KIAA0754
KIF16B kinesin family member 16B
KLC2 kinesin light chain 2
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMS2 LIM and senescent cell antigen-like domains 2
LRP2 low density lipoprotein receptor-related protein 2
LRRC15 leucine rich repeat containing 15
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEA5 melanoma antigen family A5
MMP10 matrix metallopeptidase 10
MTA2 metastasis associated 1 family, member 2
NDNF neuron-derived neurotrophic factor
NOD1 nucleotide-binding oligomerization domain containing 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTSR1 neurotensin receptor 1 (high affinity)
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PICK1 protein interacting with PRKCA 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLXNA3 plexin A3
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PSORS1C1 psoriasis susceptibility 1 candidate 1
RASL11B RAS-like, family 11, member B
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF122 ring finger protein 122
RPH3A rabphilin 3A
S100A3 S100 calcium binding protein A3
SELL selectin L
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPTBN2 spectrin, beta, non-erythrocytic 2
SYCP2 synaptonemal complex protein 2
TBX19 T-box 19
TESK1 testis-specific kinase 1
TFCP2L1 transcription factor CP2-like 1
TMEM62 transmembrane protein 62
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D4 TSC22 domain family, member 4
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR62 WD repeat domain 62
ZFHX2 zinc finger homeobox 2
ZNF219 zinc finger protein 219
ZNF234 zinc finger protein 234
ZNF334 zinc finger protein 334
ZNF37BP zinc finger protein 37B, pseudogene
ZNF41 zinc finger protein 41
ZNF446 zinc finger protein 446
ZNF573 zinc finger protein 573
ZNF74 zinc finger protein 74