ciclacillin-3882 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ciclacillin-3882 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAM23 ADAM metallopeptidase domain 23
ANKLE2 ankyrin repeat and LEM domain containing 2
AOC3 amine oxidase, copper containing 3
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
ART1 ADP-ribosyltransferase 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
C21ORF2 chromosome 21 open reading frame 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD70 CD70 molecule
CD80 CD80 molecule
CLCN1 chloride channel, voltage-sensitive 1
CLDN1 claudin 1
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CPNE7 copine VII
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCAKD dephospho-CoA kinase domain containing
DCBLD2 discoidin, CUB and LCCL domain containing 2
DESI2 desumoylating isopeptidase 2
DFNB31 deafness, autosomal recessive 31
DLC1 DLC1 Rho GTPase activating protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTX3 deltex 3, E3 ubiquitin ligase
ELOVL5 ELOVL fatty acid elongase 5
EPAS1 endothelial PAS domain protein 1
FBXL8 F-box and leucine-rich repeat protein 8
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FPR1 formyl peptide receptor 1
FUT2 fucosyltransferase 2 (secretor status included)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR182 G protein-coupled receptor 182
GRB10 growth factor receptor-bound protein 10
GSPT2 G1 to S phase transition 2
GSTP1 glutathione S-transferase pi 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUK1 guanylate kinase 1
HIST1H3F histone cluster 1, H3f
HOXA6 homeobox A6
HOXD11 homeobox D11
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM5A lysine (K)-specific demethylase 5A
LECT1 leukocyte cell derived chemotaxin 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2C myocyte enhancer factor 2C
MIP major intrinsic protein of lens fiber
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTMR1 myotubularin related protein 1
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUP188 nucleoporin 188kDa
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDGFC platelet derived growth factor C
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCL2 phospholipase C-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPL7 ribosomal protein L7
SAPCD1 suppressor APC domain containing 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SH3BP2 SH3-domain binding protein 2
SOGA1 suppressor of glucose, autophagy associated 1
SPEG SPEG complex locus
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX14 testis expressed 14
TIMP3 TIMP metallopeptidase inhibitor 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TPM2 tropomyosin 2 (beta)
TRIB2 tribbles pseudokinase 2
TTPA tocopherol (alpha) transfer protein
TUBA4B tubulin, alpha 4b
UBE3A ubiquitin protein ligase E3A
UROD uroporphyrinogen decarboxylase
USP29 ubiquitin specific peptidase 29
USP46 ubiquitin specific peptidase 46
VCL vinculin
ZIM2 zinc finger, imprinted 2
ZNF358 zinc finger protein 358
ZNF484 zinc finger protein 484
ZNF682 zinc finger protein 682

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ALOX12 arachidonate 12-lipoxygenase
AMT aminomethyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCO1 beta-carotene oxygenase 1
BIRC7 baculoviral IAP repeat containing 7
BST2 bone marrow stromal cell antigen 2
C10ORF95 chromosome 10 open reading frame 95
C22ORF46 chromosome 22 open reading frame 46
C5AR2 complement component 5a receptor 2
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CCDC85C coiled-coil domain containing 85C
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CLCN2 chloride channel, voltage-sensitive 2
CNGB3 cyclic nucleotide gated channel beta 3
CRIP1 cysteine-rich protein 1 (intestinal)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP9 dual specificity phosphatase 9
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHX2 epoxide hydrolase 2, cytoplasmic
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGL1 fibrinogen-like 1
FLCN folliculin
FLJ11710 uncharacterized protein FLJ11710
FRMD1 FERM domain containing 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
H2AFY2 H2A histone family, member Y2
HIST1H2BM histone cluster 1, H2bm
IL12RB1 interleukin 12 receptor, beta 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLK8 kallikrein-related peptidase 8
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC729164 hCG1732469
MAP2 microtubule-associated protein 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MVP major vault protein
MYO1F myosin IF
NCALD neurocalcin delta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
NPPA natriuretic peptide A
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
PMCH pro-melanin-concentrating hormone
PPT2 palmitoyl-protein thioesterase 2
RAB3A RAB3A, member RAS oncogene family
RAI2 retinoic acid induced 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF170 ring finger protein 170
RNF39 ring finger protein 39
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRT4 sirtuin 4
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX12 SRY (sex determining region Y)-box 12
SPTBN2 spectrin, beta, non-erythrocytic 2
TARP TCR gamma alternate reading frame protein
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TEX40 testis expressed 40
TFDP3 transcription factor Dp family, member 3
TMC5 transmembrane channel-like 5
TMEM121 transmembrane protein 121
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNS2 tensin 2
TRIM21 tripartite motif containing 21
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
VIM vimentin
WDR19 WD repeat domain 19
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF787 zinc finger protein 787